Results 11 to 20 of about 111,453 (186)

T helper1/T helper2 cells and resistance/susceptibility to Leishmania infection : is this paradigm still relevant? [PDF]

, 2012
Work in large part on Leishmania major in the 1980s identified two distinct apparently counter-regulatory CD4 T cell populations, T helper (h)1 and Th2, that controlled resistance/susceptibility to infection respectively.
Brombacher, F., Alexander, J.
core   +4 more sources

Metabolic variation during development in culture of Leishmania donovani promastigotes [PDF]

, 2011
The genome sequencing of several Leishmania species has provided immense amounts of data and allowed the prediction of the metabolic pathways potentially operating.
Cordeiro-da-Silva, Anabela, Coombs, Graham H, Silva, Ana Marta   +2 more
core   +5 more sources

The role of surface glycoconjugates in Leishmania midgut attachment examined by competitive binding assays and experimental development in sand flies [PDF]

, 2013
SUMMARY Binding of promastigotes to the sand fly midgut epithelium is regarded as an essential part of the Leishmania life cycle in the vector. Among Leishmania surface molecules putatively involved in attachment to the sand fly midgut, two GPI-anchored ...
Jecna, Lucie, Bates, Paul A., Seblova, Veronika, Volf, Petr, Dostalova, Anna, Wilson, Ray, Chang, Kwang-Poo   +6 more
core   +5 more sources

High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase [PDF]

, 2011
Background: Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent kinases (CDKs). Cdc2-related kinase 3 (CRK3), an essential CDK in Leishmania and functional orthologue of human CDK1, can form ...
Walker, Roderick G., Brown, Elaine, Thomson, Graeme, Blake, David G., Malone, Kirk, Turner, Nicholas J., Grant, Karen, Mottram, Jeremy C., Walkinshaw, Malcolm D., Nowicki, Matthew W.   +9 more
core   +3 more sources

A real-time PCR assay to estimate Leishmania chagasi load in its natural sand fly vector Lutzomyia longipalpis [PDF]

, 2008
Leishmania chagasi, transmitted mainly by Lutzomyia longipalpis sand flies, causes visceral leishmaniasis and atypical cutaneous leishmaniasis in Latin America.
Bates, Paul A., Maingon, Rhayza D.C., Ranasinghe, Shalindra, Ranasinghe, S., Rogers, Matthew E., Hamilton, J. G. C., Maingon, Rhayza DC, Rogers, Matthew E, Bates, Paul, Hamilton, James G C, Maingon, Rhayza D C, Hamilton, James GC, Maingon, R. D. C., Hamilton, James G.C., Bates, Paul A   +14 more
core   +1 more source

Complex ecological interactions across a focus of cutaneous leishmaniasis in Eastern Colombia: novel description of Leishmania species, hosts and phlebotomine fauna [PDF]

Royal Society Open Science, 2020
This study aimed to analyse the patterns of diversity, blood sources and Leishmania species of phlebotomines in a focus of cutaneous leishmaniasis in Arboledas, Eastern Colombia.
Claudia M. Sandoval-Ramírez, Carolina Hernández, Aníbal A. Teherán, Reinaldo Gutierrez-Marin, Ruth A. Martínez-Vega, Duvan Morales, Richard Hoyos-Lopez, Astrid Araque-Mogollón, Juan David Ramírez   +8 more
doaj   +1 more source

Leishmania manipulation of sand fly feeding behavior results in enhanced transmission [PDF]

, 2007
In nature the prevalence of Leishmania infection in whole sand fly populations can be very low (
Rogers, Matthew E, Bates, Paul A
core   +5 more sources

Trends in malaria indicators after scale-up of community-based malaria management in Afghanistan

Malaria Journal, 2022
Background The Community-Based Malaria Management (CBMM) strategy, introduced in 2013 and expanded to all health facilities and health posts in Afghanistan by 2016, aimed to deliver rapid diagnostic testing and more timely treatment to all communities ...
Sayed Daoud Mahmoodi, Abdul Alim Atarud, Ahmad Walid Sediqi, Sarah Gallalee, Willi McFarland, Temesgen Birara Aynie, Mohmmad Sami Nahzat, Hamida Hamid, Ghulam Qader Qader, Mohammad Shoaib Tamim, Ali Mirzazadeh   +10 more
doaj   +1 more source

Leishmania isoenzyme polymorphisms in Ecuador: Relationships with geographic distribution and clinical presentation [PDF]

, 2006
Background: Determinants of the clinical presentation of the leishmaniases are poorly understood but Leishmania species and strain differences are important.
Cooper Philip J, Masataka Korenaga, Marco Jorge D, Korenaga, Masataka, Rodrigo X Armijos, Hirotomo Kato, Paola A Barroso, Kato Hirotomo, Korenaga, M, Gomez, EA, Calvopina Manuel, Kato, Hirotomo, Hiroshi Uezato, Barroso, Paola A., Armijos, Rodrigo X., Cooper, PJ, Yoshihisa Hashiguchi, Shigeo Nonaka, Nonaka Shigeo, Gomez Eduardo A, Manuel Calvopina, Marco, Jorge D., Kato, H, Barroso Paola A, Mimori, Tatsuyuki, Armijos, RX, Hashiguchi, Y, Nonaka, Shigeo, Eduardo A Gomez, Calvopina, M, Marco, JD, Korenaga Masataka, Tatsuyuki Mimori, Uezato, H, Jorge D Marco, Gomez, Eduardo A., Calvopina, Manuel, Mimori Tatsuyuki, Manuel Calvopina, Uezato Hiroshi, Cooper, Philip J., Hashiguchi, Yoshihisa, Mimori, T, Philip J Cooper, Nonaka, S, Uezato, Hiroshi, Armijos Rodrigo X, Barroso, PA, Hashiguchi Yoshihisa   +48 more
core   +2 more sources

Phlebotomine sand flies (Diptera: Psychodidae) associated with changing patterns in the transmission of the human cutaneous leishmaniasis in French Guiana

Memorias do Instituto Oswaldo Cruz, 2007
Between March 2000 and December 2001 a survey of the sand flies (Diptera: Phlebotominae) of French Guiana was carried out during 14 nights of captures with CDC light-traps and Malaise traps, and resulted in the collection of 2245 individuals of 38 ...
Florence Fouque, Pascal Gaborit, Jean Issaly, Romuald Carinci, Jean-Charles Gantier, Christophe Ravel, Jean-Pierre Dedet   +6 more
doaj   +1 more source