Inhibition of growth of Leishmania mexicana mexicana by Leishmania mexicana amazonensis during "in vitro" co-cultivation Inibição do crescimento de Leishmania mexicana mexicana por Leishmania mexicana amazonensis durante o co-cultivo "in vitro" [PDF]
Memorias do Instituto Oswaldo Cruz, 1987 Inhibition of one Leishmania subspecies by exometabolites of another subspecies, a phenomenon not previously reported, is suggested by our recent observations in cell cloning experiments with Leishmania mexicana mexicana and Leishmania mexicana ...
Raquel S. Pacheco +2 more
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Unique Leishmania mexicana clones secrete populations of extracellular vesicles with unique protein profile and variable infectious capability [PDF]
Frontiers in Cellular and Infection MicrobiologyThe study of extracellular vesicles has become an incredibly important field of study, but the inherent heterogeneity of these vesicles continues to make their study challenging.
George Dong +4 more
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Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection [PDF]
Parasites & Vectors, 2014 Background Phlebotomine sand flies transmit the haemoflagellate Leishmania, the causative agent of human leishmaniasis. The Leishmania promastigotes are confined to the gut lumen and are exposed to the gut microbiota within female sand flies.
Mauricio RV Sant’Anna +8 more
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Inhibitory Effects of Leishmania Mexicana infection on MHC-I Expression in Bone Marrow Derived Dendritic Cells [PDF]
Iranian Journal of Parasitology, 2022 Background: Leishmania is a parasite causing leishmaniasis with different clinical manifestations depending on the infectious species in many countries worldwide.
Hossein Rezvan +2 more
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Triose Phosphate Isomerase Structure-Based Virtual Screening and In Vitro Biological Activity of Natural Products as Leishmania mexicana Inhibitors [PDF]
Pharmaceutics, 2023 Cutaneous leishmaniasis (CL) is a public health problem affecting more than 98 countries worldwide. No vaccine is available to prevent the disease, and available medical treatments cause serious side effects.
Luis D. González-Morales +10 more
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Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2017 Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Khalid J.H. Alzahrani +7 more
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Human Dendritic Cell Maturation Is Modulated by Leishmania mexicana through Akt Signaling Pathway [PDF]
Tropical Medicine and Infectious DiseaseDendritic cells (DC) along with macrophages are the main host cells of the intracellular parasite Leishmania. DC traverse a process of maturation, passing through an immature state with phagocytic ability to a mature one where they can modulate the ...
Jorge Rodríguez-González +2 more
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Endocytosis and Sphingolipid Scavenging in Leishmania mexicana Amastigotes [PDF]
Biochemistry Research International, 2012 Leishmania species are the causative agents of the leishmaniases, a spectrum of neglected tropical diseases. Amastigote stage parasites exist within macrophages and scavenge host factors for survival, for example, Leishmania species utilise host ...
Hayder Z. Ali +2 more
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The DNA polymerases ofLeishmania mexicana [PDF]
FEMS Microbiology Letters, 1992 Two previously isolated DNA polymerases from the parasitic protozoan Leishmania mexicana were further characterized by exposure to inhibitors of mammalian DNA polymerases. DNA polymerase A, a high molecular mass enzyme, and DNA polymerase B, a beta-like DNA polymerase were compared to each other and to their mammalian counterparts regarding pH optimum,
L L, Nolan, J H, Rivera
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Revista da Sociedade Brasileira de Medicina Tropical, 1985 Three isolates of Leishmania were recovered from five of 27 specimens of the rodent Proechimys iheringi denigratus Moojen captured near Três Braços in the Atlantic Forest region of Bahia, Brazil.
Air C. Barretto +7 more
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