Inhibition of growth of Leishmania mexicana mexicana by Leishmania mexicana amazonensis during "in vitro" co-cultivation Inibição do crescimento de Leishmania mexicana mexicana por Leishmania mexicana amazonensis durante o co-cultivo "in vitro" [PDF]
Inhibition of one Leishmania subspecies by exometabolites of another subspecies, a phenomenon not previously reported, is suggested by our recent observations in cell cloning experiments with Leishmania mexicana mexicana and Leishmania mexicana ...
Raquel S. Pacheco +2 more
doaj +6 more sources
Unique Leishmania mexicana clones secrete populations of extracellular vesicles with unique protein profile and variable infectious capability [PDF]
The study of extracellular vesicles has become an incredibly important field of study, but the inherent heterogeneity of these vesicles continues to make their study challenging.
George Dong +4 more
doaj +2 more sources
Inhibitory Effects of Leishmania Mexicana infection on MHC-I Expression in Bone Marrow Derived Dendritic Cells [PDF]
Background: Leishmania is a parasite causing leishmaniasis with different clinical manifestations depending on the infectious species in many countries worldwide.
Hossein Rezvan +2 more
doaj +2 more sources
Triose Phosphate Isomerase Structure-Based Virtual Screening and In Vitro Biological Activity of Natural Products as Leishmania mexicana Inhibitors [PDF]
Cutaneous leishmaniasis (CL) is a public health problem affecting more than 98 countries worldwide. No vaccine is available to prevent the disease, and available medical treatments cause serious side effects.
Luis D. González-Morales +10 more
doaj +2 more sources
Human Dendritic Cell Maturation Is Modulated by Leishmania mexicana through Akt Signaling Pathway [PDF]
Dendritic cells (DC) along with macrophages are the main host cells of the intracellular parasite Leishmania. DC traverse a process of maturation, passing through an immature state with phagocytic ability to a mature one where they can modulate the ...
Jorge Rodríguez-González +2 more
doaj +2 more sources
Immunity to Leishmania mexicana parasite [PDF]
Background: Cutaneous Leishmaniasis caused by the Leishmania mexicana complex is associated with unpleasant or disfiguring lesions, for which there only limited treatment options. The life cycle of L. mexicana consists of two stages which involve different immune evasion mechanisms: promastigote and amastigote. Understanding parasitic interactions with
Ali, KSM
openaire +1 more source
Studies on immunology of Leishmania mexicana [PDF]
Leishmaniasis is a worldwide disease prevalent in many tropical and sub tropical countries. Treatment of Leishmaniasis by chemotherapy is not wholly effective and is usually accompanied by unpleasant side effects. The development of an effective and inexpensive vaccine represents a practical way to control the disease, however at present no safe and ...
Rezvan, H, Rezvan, Hossein
openaire +1 more source
Endocytosis and Sphingolipid Scavenging in Leishmania mexicana Amastigotes [PDF]
Leishmania species are the causative agents of the leishmaniases, a spectrum of neglected tropical diseases. Amastigote stage parasites exist within macrophages and scavenge host factors for survival, for example, Leishmania species utilise host ...
Hayder Z. Ali +2 more
doaj +5 more sources
The DNA polymerases ofLeishmania mexicana [PDF]
Two previously isolated DNA polymerases from the parasitic protozoan Leishmania mexicana were further characterized by exposure to inhibitors of mammalian DNA polymerases. DNA polymerase A, a high molecular mass enzyme, and DNA polymerase B, a beta-like DNA polymerase were compared to each other and to their mammalian counterparts regarding pH optimum,
L L, Nolan, J H, Rivera
openaire +2 more sources
Three isolates of Leishmania were recovered from five of 27 specimens of the rodent Proechimys iheringi denigratus Moojen captured near Três Braços in the Atlantic Forest region of Bahia, Brazil.
Air C. Barretto +7 more
doaj +3 more sources

