BACKGROUND The transmission routes for American cutaneous leishmaniasis (ACL) are in flux, so studies examining its transmission in humans, mammalian hosts, and sand fly vectors are urgently needed.
Annhymariet Torrellas +10 more
doaj +1 more source
The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host [PDF]
Bardet–Biedl syndrome (BBS) is a human genetic disorder with a spectrum of symptoms caused by primary cilium dysfunction. The disease is caused by mutations in one of at least 17 identified genes, of which seven encode subunits of the BBSome, a protein ...
Doehl, Johannes +6 more
core +1 more source
Native rodent species are unlikely sources of infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru. [PDF]
An estimated 2.3 million disability-adjusted life years are lost globally from leishmaniasis. In Peru's Amazon region, the department of Madre de Dios (MDD) rises above the rest of the country in terms of the annual incidence rates of human leishmaniasis.
Conrad, Patricia A +7 more
core +11 more sources
DNA hybridisation, using probes labelled with 32P, was used to type Leishmania samples isolated from patients living in endemic areas of Mato Grosso State (Brazil), and clinically diagnosed as having tegumentary leishmaniasis.
Antero Silva Ribeiro de Andrade +5 more
doaj +1 more source
The recombinant cysteine proteinase B (CPB) from Leishmania braziliensis and its domains: promising antigens for serodiagnosis of cutaneous and visceral leishmaniasis in dogs. [PDF]
Leishmaniasis represents a group of parasitic diseases caused by a protozoan of the genus Leishmania and is widely distributed in tropical and subtropical regions.
Basombrío, Manuel Alberto +10 more
core +1 more source
Utilizando parámetros biométricos de la fase amastigota y el tipo de desarrollo de los parásitos en el flebótomo Lutzomyia townsendi, se han estudiado cuatro aislados de Leishmania obtenidos de pacientes con leishmaniasis cutánea difusa, comparándolos ...
J. V. Scorza, O. Delgado
doaj +1 more source
Changes to cholesterol trafficking in macrophages by Leishmania parasites infection [PDF]
Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases.
Anderson +67 more
core +2 more sources
The effect of Marigold flower extracts on growth of Leishmania. [PDF]
This study searched in the inhibiting potency of different concentrations (12.5, 25, 50 and 100 µg/mL) of both aqueous and methanol extracts of marigold plant flower Calendula officinalis against the promastigote of Leismania major, L. donovani and
Neama Ali Ahmad
doaj +1 more source
The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models. [PDF]
Toll-like receptors (TLRs) play an important role in the innate and adaptive immune responses to pathogens, and are the target of new vaccine adjuvants.
Bates, PA +4 more
core +7 more sources
Stage-specific proteinases ofLeishmania mexicana mexicanapromastigotes [PDF]
Four distinct bands of cysteine proteinase activity were detected when stationary-phase populations of Leishmania mexicana mexicana were subjected to gelatin-SDS-PAGE. The highest mobility band contained at least three isoforms separable by mono Q anion exchange chromatography.
C D, Robertson, G H, Coombs
openaire +2 more sources

