Genome-wide mapping reveals single-origin chromosome replication in Leishmania, a eukaryotic microbe [PDF]
Background DNA replication initiates on defined genome sites, termed origins. Origin usage appears to follow common rules in the eukaryotic organisms examined to date: all chromosomes are replicated from multiple origins, which display variations in ...
Campbell, Samantha J. +4 more
core +2 more sources
The study of cells using scanning force microscopy [PDF]
In nature the prevalence of Leishmania infection in whole sand fly populations can be very low (
Eley, AR +5 more
core +9 more sources
Introducción. El mapa de la distribución de especies de Leishmania en Colombia no se ha actualizado desde hace siete años. Objetivo. Describir la distribución de las especies de Leishmania a partir de los aislamientos de pacientes consultantes al ...
Clemencia Elena Ovalle +4 more
doaj +1 more source
Impact of Leishmania mexicana infection on dendritic cell signaling and functions. [PDF]
Leishmania parasites have the ability to modify macrophage signaling pathways in order to survive and multiply within its mammalian host. They are also known to invade other cells including neutrophils, fibroblasts and dendritic cells (DCs).
Irazú Contreras +9 more
doaj +1 more source
Parasites belonging to Leishmania braziliensis, Leishmania donovani, Leishmania mexicana complexes and Trypanosoma cruzi (clones 20 and 39) were searched in blood, lesions and strains collected from 28 patients with active cutaneous leishmaniasis and one
B Bastrenta +9 more
doaj +1 more source
Intra- and interspecific polymorphisms ofLeishmania donovani andL. tropica minicircle DNA [PDF]
A pair of degenerate polymerase chain reaction (PCR) primers (LEI-1, TCG GAT CC[C,T] [G,C]TG GGT AGG GGC GT; LEI-2, ACG GAT CC[G,C] [G,C][A,C]C TAT [A,T]TT ACA CC) defining a 0.15-kb segment ofLeishmania minicircle DNA was constructed.
AJ Magill +16 more
core +1 more source
Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni +9 more
core +1 more source
Leishmania mexicana Gp63 cDNA Using Gene Gun Induced Higher Immunity to L. mexicana Infection Compared to Soluble Leishmania Antigen in BALB/C [PDF]
Background: Leishmaniasis is a worldwide disease prevalent in tropical and sub tropical countries. Many attempts have been made and different strategies have been approached to develop a potent vaccine against Leishmania.
H Rezvan, R Rees, SA Ali
doaj +1 more source
American cutaneous leishmaniasis includes a spectrum of clinical forms localized cutaneous, diffuse cutaneous, and mucocutaneous leishmaniasis which can be caused by different strains of Leishmania belonging to the L. mexicana or L.
Amalia Monroy-Ostria +4 more
doaj +1 more source
Detection and identification of Leishmania species within naturally infected sand flies in the Andean areas of Ecuador by a polymerase chain reaction [PDF]
The surveillance of prevalent Leishmania and sand fly species in endemic areas is important for prediction of the risk and expansion of leishmaniasis. In this study, we developed a polymerase chain reaction (PCR)-based method for detection of Leishmania ...
Barroso, Paola Andrea +11 more
core +1 more source

