Results 31 to 40 of about 7,407 (178)

Leishmania mexicana mexicana: quantitative analysis of the intracellular cycle

Parasitology, 1989
SummaryThe complete intracellular cycle of theLeishmania mexicana mexicanaG. S. strain was quantified in human macrophages and in the mouse IC-21 macrophage line utilizing a culture system that allows the direct observation of individual intracellular parasites.
P S, Doyle, J C, Engel, A A, Gam, J A, Dvorak   +3 more
openaire   +2 more sources

Biological Evaluation, Molecular Docking, MD Simulation Study and Synthesis of (Z)‐N’‐(3‐phenoxybenzylidene)‐2‐(substituted‐amino aryl) Acetohydrazid

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Synthesis and biological evaluation (antibacterial, antifungal, anti‐tuberculosis, antiprotozoal) and in silico molecular docking of biphenyl ether based Schiff's base analogues. ABSTRACT In order to investigate their possible biological activity, a number of new Schiff base compounds based on diaryl ether, specifically 2‐(substituted‐arylamino)‐N′‐(3 ...
Navin B. Patel, Deepti S. Ghaisas, Vatsal M. Patel, Faiyazalam M. Shaikh, Mohit Agrawal, Mohd Imran, Gildardo Rivera, Hetal I. Soni   +7 more
wiley   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Byrsonima crassifolia: Ethnobotany, Phytochemistry, and Pharmacology – An Update

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Current knowledge on B. crassifolia is integrated, linking its phytochemical diversity with reported pharmacological activities and highlighting the therapeutic potential of this medicinal species. ABSTRACT Byrsonima crassifolia is a fruit‐bearing species widely distributed across tropical regions of the Americas with potential health applications ...
João de Jesus Oliveira Junior, Débora Luana Ribeiro Pessoa, Marilene Oliveira da Rocha Borges   +2 more
wiley   +1 more source

Purification and Characterization of Proteolytic Enzymes of Leishmania mexicana mexicana Amastigotes and Promastigotes [PDF]

Microbiology, 1984
Leishmania mexicana mexicana amastigote and promastigote soluble proteinases were purified using gel filtration and ion exchange chromatography. For the amastigotes, two main proteinase activity peaks were separated with both methods. These accounted for approximately 10% and 90% of the total activity.
M F, Pupkis, G H, Coombs
openaire   +2 more sources

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

Immunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros, Gabriel Augusto Leite, Arthur Gomes de Andrade, Maria Danielma dos Santos Reis, Luiz Henrique Agra Cavalcante‐Silva, Marvin Paulo Lins   +5 more
wiley   +1 more source

Presencia de nectomonadas metaciclicas de L. pifanoi en la hipofaringe de Lutzomyia youngi y la ingestion de azúcares Metacyclical forms of L. pifanoi in the hypopharynx of Lutzomyia youngi and their sugar consumption

Revista de Saúde Pública, 1996
Se evidencia la presencia de promastigotos metacíclicos de Leishmania pifanoi en el conducto hipofaríngeo de Lutzomyia youngi infectados experimentalmente por ingurgitación sobre lesiones tarsales de hámsteres.
Elina Rojas, José V. Scorza
doaj   +1 more source

Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose, Irit Dahan, Alexander Upcher, Ran Zalk, Iris Grossman‐Haham   +4 more
wiley   +1 more source

Ecology of phlebotomine sandflies and putative reservoir hosts of leishmaniasis in a border area in Northeastern Mexico: implications for the risk of transmission of Leishmania mexicana in Mexico and the USA

Parasite, 2017
Leishmaniases are a group of important diseases transmitted to humans through the bite of sandfly vectors. Several forms of leishmaniases are endemic in Mexico and especially in the Southeast region.
Rodríguez-Rojas Jorge J., Rodríguez-Moreno Ángel, Berzunza-Cruz Miriam, Gutiérrez-Granados Gabriel, Becker Ingeborg, Sánchez-Cordero Victor, Stephens Christopher R., Fernández-Salas Ildefonso, Rebollar-Téllez Eduardo A.   +8 more
doaj   +1 more source

Down-Regulation of TLR and JAK/STAT Pathway Genes Is Associated with Diffuse Cutaneous Leishmaniasis: A Gene Expression Analysis in NK Cells from Patients Infected with Leishmania mexicana. [PDF]

PLoS Neglected Tropical Diseases, 2016
An important NK-cell inhibition with reduced TNF-α, IFN-γ and TLR2 expression had previously been identified in patients with diffuse cutaneous leishmaniasis (DCL) infected with Leishmania mexicana.
Edith A Fernández-Figueroa, Iván Imaz-Rosshandler, Juan E Castillo-Fernández, Haydee Miranda-Ortíz, Juan C Fernández-López, Ingeborg Becker, Claudia Rangel-Escareño   +6 more
doaj   +1 more source