Results 51 to 60 of about 9,040 (224)

Proteophosophoglycans regurgitated by Leishmania-infected sand flies target the L-arginine metabolism of host macrophages to promote parasite survival [PDF]

open access: yes, 2009
All natural Leishmania infections start in the skin; however, little is known of the contribution made by the sand fly vector to the earliest events in mammalian infection, especially in inflamed skin that can rapidly kill invading parasites.
Podinovskaia, M   +32 more
core   +1 more source

Green Synthesis of Metal Oxide Nanoparticles Using Plant Extracts: Applications in Catalysis and Biomedicine

open access: yesNano Select, Volume 7, Issue 3, March 2026.
ABSTRACT The green synthesis of metal oxide nanoparticles (MONPs) using plant‐based resources has gained significant traction as an environmentally benign, cost‐effective, and scalable alternative to traditional chemical and physical methods. This review comprehensively explores the plant‐mediated synthesis routes for a variety of MONPs, including CuO,
Faith Mwangi, Jannatun Zia, Ufana Riaz
wiley   +1 more source

Ecology of phlebotomine sandflies and putative reservoir hosts of leishmaniasis in a border area in Northeastern Mexico: implications for the risk of transmission of Leishmania mexicana in Mexico and the USA

open access: yesParasite, 2017
Leishmaniases are a group of important diseases transmitted to humans through the bite of sandfly vectors. Several forms of leishmaniases are endemic in Mexico and especially in the Southeast region.
Rodríguez-Rojas Jorge J.   +8 more
doaj   +1 more source

Presencia de nectomonadas metaciclicas de L. pifanoi en la hipofaringe de Lutzomyia youngi y la ingestion de azúcares Metacyclical forms of L. pifanoi in the hypopharynx of Lutzomyia youngi and their sugar consumption

open access: yesRevista de Saúde Pública, 1996
Se evidencia la presencia de promastigotos metacíclicos de Leishmania pifanoi en el conducto hipofaríngeo de Lutzomyia youngi infectados experimentalmente por ingurgitación sobre lesiones tarsales de hámsteres.
Elina Rojas, José V. Scorza
doaj   +1 more source

Down-Regulation of TLR and JAK/STAT Pathway Genes Is Associated with Diffuse Cutaneous Leishmaniasis: A Gene Expression Analysis in NK Cells from Patients Infected with Leishmania mexicana. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
An important NK-cell inhibition with reduced TNF-α, IFN-γ and TLR2 expression had previously been identified in patients with diffuse cutaneous leishmaniasis (DCL) infected with Leishmania mexicana.
Edith A Fernández-Figueroa   +6 more
doaj   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1754-1770, March 2026.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini   +6 more
wiley   +1 more source

Purification and Characterization of Proteolytic Enzymes of Leishmania mexicana mexicana Amastigotes and Promastigotes [PDF]

open access: yesMicrobiology, 1984
Leishmania mexicana mexicana amastigote and promastigote soluble proteinases were purified using gel filtration and ion exchange chromatography. For the amastigotes, two main proteinase activity peaks were separated with both methods. These accounted for approximately 10% and 90% of the total activity.
M F, Pupkis, G H, Coombs
openaire   +2 more sources

Sex‐Specific Factors Influencing HIV Infection

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

IgG1 Is Pathogenic in Leishmania mexicana Infection [PDF]

open access: yesThe Journal of Immunology, 2010
Abstract There are >2 million new cases of leishmaniasis annually, and no effective vaccine has been developed to prevent infection. In murine infection, Leishmania mexicana, which lives intracellularly in host macrophages, has developed pathways to hijack host IgG to induce a suppressive IL-10 response through FcγRs, the cell ...
Niansheng, Chu   +3 more
openaire   +2 more sources

Leishmania isoenzyme polymorphisms in Ecuador: Relationships with geographic distribution and clinical presentation

open access: yes, 2006
Background: Determinants of the clinical presentation of the leishmaniases are poorly understood but Leishmania species and strain differences are important.
Cooper Philip J   +48 more
core   +1 more source

Home - About - Disclaimer - Privacy