Results 71 to 80 of about 7,407 (178)

LmxM.22.0250-Encoded Dual Specificity Protein/Lipid Phosphatase Impairs Leishmania mexicana Virulence In Vitro

Pathogens, 2019
Protein phosphorylation/dephosphorylation is an important regulatory mechanism that controls many key physiological processes. Numerous pathogens successfully use kinases and phosphatases to internalize, replicate, and survive, modifying the host′s
Natalya Kraeva, Tereza Leštinová, Aygul Ishemgulova, Karolina Majerová, Anzhelika Butenko, Slavica Vaselek, Julia Bespyatykh, Arzuv Charyyeva, Tatiana Spitzová, Alexei Yu. Kostygov, Julius Lukeš, Petr Volf, Jan Votýpka, Vyacheslav Yurchenko   +13 more
doaj   +1 more source

Cellular landmarks of Trypanosoma brucei and Leishmania mexicana

Molecular and Biochemical Parasitology, 2019
The kinetoplastids Trypanosoma brucei and Leishmania mexicana are eukaryotes with a highly structured cellular organisation that is reproduced with great fidelity in each generation. The pattern of signal from a fluorescently tagged protein can define the specific structure/organelle that this protein localises to, and can be extremely informative in ...
Halliday, Clare, Billington, Karen, Wang, Ziyin, Madden, Ross, Dean, Samuel, Sunter, Jack Daniel, Wheeler, Richard John   +6 more
openaire   +3 more sources

Identification of Leishmania mexicana mexicana in the State of São Paulo, Brazil.

Revista do Instituto de Medicina Tropical de Sao Paulo, 1983
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Machado, M. I., Milder, R. V., Grimaldi Júnior, G., Momen, H.   +3 more
openaire   +2 more sources

Intralysosomal pathogens differentially influence the proteolytic potential of their niche

Infection and Immunity
Avoiding lysosomal degradation is vital to the success of intracellular pathogens. The Gram-negative bacterium Coxiella burnetii and protozoan parasites of the Leishmania genus are unique in being able to replicate within the mature phagolysosomal ...
Lauren E. Bird, Bangyan Xu, David R. Thomas, Erin N. S. McGowan, Patrice Newton, Nichollas E. Scott, Malcolm J. McConville, Laura E. Edgington-Mitchell, Hayley J. Newton   +8 more
doaj   +1 more source

Leishmania mexicana: aspectos taxonómicos y rareza de la infección humana en Três Braços, Bahia, Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 1984
Del estúdio de 51 stocks de Leishmania aislados de pacientes humanos de leishmaniasis cutaneomucosa en Três Braços, Bahia, Brasil, los autores describen, en detalle, el análisis de los dos únicos stocks de L.
César Augusto Cuba Cuba, Air Colombo Barreto, Philip Davis Marsden   +2 more
doaj  

Novel hydroxynaphthalene and quinoline derivatives effective against Trypanosoma and Leishmania

ADMET and DMPK
Background and purpose: The increasing prevalence of multidrug-resistant parasites, particularly Trypanosoma and Leishmania, together with the limited efficacy of current therapies, highlights the need for new antiprotozoal agents.
Tomas Gonec, Tomas Strharsky, Marcela Vettorazzi, Lucas Gutierrez, Martina Cudova, Tereza Kauerova, Michaela Simurdova, Michal Oravec, Jiří Kos, Peter Kollar, Bohuslav Drahos, Jan Jurica, Ondrej Zendulka, Jana Gregorova, Ondrej Pes, Joelle Quetin-Leclercq, Josef Jampilek, Ricardo Daniel Enriz   +17 more
doaj   +1 more source

Leishmania mexicana promotes pain-reducing metabolomic reprogramming in cutaneous lesions. [PDF]

iScience, 2023
Volpedo G, Oljuskin T, Cox B, Mercado Y, Askwith C, Azodi N, Bernier M, Nakhasi HL, Gannavaram S, Satoskar AR.   +9 more
europepmc   +1 more source

Leishmania mexicana [PDF]

, 2020
openaire   +1 more source

Inhibition of HSP90 distinctively modulates the global phosphoproteome of <i>Leishmania mexicana</i> developmental stages. [PDF]

Microbiol Spectr, 2023
Porta EO, Gao L, Denny PW, Steel PG, Kalesh K.   +4 more
europepmc   +1 more source

Immunity to Leishmania mexicana parasite [PDF]

, 2014
Background: Cutaneous Leishmaniasis caused by the Leishmania mexicana complex is associated with unpleasant or disfiguring lesions, for which there only limited treatment options. The life cycle of L. mexicana consists of two stages which involve different immune evasion mechanisms: promastigote and amastigote. Understanding parasitic interactions with
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