Results 61 to 70 of about 14,552 (222)

Sex‐Specific Factors Influencing HIV Infection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

IgG1 Is Pathogenic in Leishmania mexicana Infection [PDF]

The Journal of Immunology, 2010
Abstract There are >2 million new cases of leishmaniasis annually, and no effective vaccine has been developed to prevent infection. In murine infection, Leishmania mexicana, which lives intracellularly in host macrophages, has developed pathways to hijack host IgG to induce a suppressive IL-10 response through FcγRs, the cell ...
Niansheng, Chu, Bolaji N, Thomas, Supriya R, Patel, Laurence U, Buxbaum   +3 more
openaire   +2 more sources

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

Ecology of phlebotomine sandflies and putative reservoir hosts of leishmaniasis in a border area in Northeastern Mexico: implications for the risk of transmission of Leishmania mexicana in Mexico and the USA

Parasite, 2017
Leishmaniases are a group of important diseases transmitted to humans through the bite of sandfly vectors. Several forms of leishmaniases are endemic in Mexico and especially in the Southeast region.
Rodríguez-Rojas Jorge J., Rodríguez-Moreno Ángel, Berzunza-Cruz Miriam, Gutiérrez-Granados Gabriel, Becker Ingeborg, Sánchez-Cordero Victor, Stephens Christopher R., Fernández-Salas Ildefonso, Rebollar-Téllez Eduardo A.   +8 more
doaj   +1 more source

Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis. [PDF]

, 2017
The 4-aminoquinoline chloroquine (CQ) is clinically used in combination with doxycycline to cure chronic Q fever, as it enhances the activity of the antibiotic against the causative bacterium Coxiella burnetii residing within macrophage phagolysosomes ...
Croft, Simon L, Murdan, Sudaxshina, Van Bocxlaer, Katrien, Wijnant, Gert-Jan, Yardley, Vanessa   +4 more
core   +2 more sources

Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection

Parasite Immunology, Volume 48, Issue 1, January 2026.
ABSTRACT Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a ...
Arieli Bernardo Portugal, Renato Augusto DaMatta, Edézio Ferreira da Cunha Júnior, João Luiz Mendes Wanderley   +3 more
wiley   +1 more source

Seroepidemiology and molecular diversity of Leishmania donovani complex in Georgia [PDF]

, 2016
Background Leishmaniasis includes multiple clinical syndromes, most notably visceral, cutaneous, and mucosal forms. Visceral leishmaniasis (VL), also known as kala-azar, is a potentially fatal disease endemic to large parts of Africa and Asia, and in ...
Adeishvili, Ekaterine, Babuadze, Giorgi, Carrillo, Eugenia, Chakhunashvili, Giorgi, Chanturia, Gvantsa, De Koning, Harry P., Farlow, Jason, Imnadze, Paata, Kalandadze, Irine, Karseladze, Irakli, Kekelidze, Merab, Kokaia, Nora, Markhvashvili, Ivane, Murskvaladze, Mari, Sidamonidze, Ketevan, Tsereteli, David   +15 more
core   +3 more sources

Evidence Gaps and Global Patterns in Leishmaniasis Control: A Scoping Review of Clinical, Diagnostic, and Treatment Strategies

Journal of Parasitology Research, Volume 2026, Issue 1, 2026.
Background Leishmaniasis is a neglected tropical disease with diverse clinical forms, heterogeneous geographical distribution, and persistent diagnostic and treatment challenges. Although substantial primary research exists, evidence remains fragmented, limiting integrated and context‐specific control strategies.
Muhi-deen Wonwana Mohammed, Yussif Owusu Aboagye, Akwasi Anyanful, Samuel Kyei, Kwame Kumi Asare, Pengfei Cai   +5 more
wiley   +1 more source

Visceral Leishmaniosis caused by Leishmania (L.) mexicana in a Mexican patient with human immunodeficiency virus infection

Memorias do Instituto Oswaldo Cruz, 2000
A 36 year old male was admitted in December 1997 to hospital with afternoon fever, malaise and hepatosplenomegaly. He also had a dry cough, dyspnoea and anaemia.
Carmen Ramos-Santos, Omar Hernandez-Montes, Gustavo Sanchez-Tejeda, Amalia Monroy-Ostria   +3 more
doaj   +1 more source

Eprinomectin Inhibits Leishmania by Inducing Mitochondrial Dysfunction and Cell Cycle Arrest

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Introduction Leishmaniasis remains a significant global health challenge, with current therapies often hampered by toxicity, resistance, and high cost. In this study, we investigated the antileishmanial potential of eprinomectin, a veterinary macrocyclic lactone, to address unmet therapeutic needs.
Mengtao Yu, Jiale Guo, Wenqi Liu, Yan Li, B. Shen   +4 more
wiley   +1 more source