Results 21 to 30 of about 111,453 (186)

Leishmania infantum and dog : immunological and epidemiological studies about infection and disease [PDF]

, 2001
L'objectiu d'aquesta tesi va ser obtenir nous coneixements sobre la immunologia i epidemiologia de la infecció per Leishmania en gossos que viuen en zones endèmiques.
Alberola, Jordi, Solano Gallego, Laia
core   +1 more source

Is it time to revise the nomenclature of Leishmania?

, 2010
Leishmania is notable for a large number of described species. Molecular phylogenies of Leishmania have increasingly suggested that the number of species could be too large.
Mauricio, Isabel, Gabriele Schönian, Isabel Mauricio, Cupolillo, Elisa, Elisa Cupolillo, Schönian, Gabriele   +5 more
core   +1 more source

Visualization of Leishmania tropica Infection in BALB/c Mice by Bioluminescence Imaging

Iranian Biomedical Journal, 2020
Background: Leishmania tropica is the cause of more than one form of leishmaniasis and lacks a known reservoir animal. This study compares the potential infectivity of recombinant and wild-type L. tropica in BALB/c mice.
Mahdieh Eskandar, Elham Gholami, Negar Seyed, Yasaman Taslimi, Sima Habibzadeh, Sima Rafati, Tahereh Taheri   +6 more
doaj  

Bulky pcDNA plasmid encoding Leishmania- and Sandfly-derived antigens resulted in transient Th1 response post Leishmania major infection in BALB/c mice

Scientific Reports
Leishmaniasis is a common parasitic infection in tropical regions worldwide, and yet there is no effective human vaccine available. The results of leishmanization in animal models have emphasized the role of antigen persistence after recovery from the ...
Negar Seyed, Hamzeh Sarvnaz, Sima Habibzadeh, Roya Yousefi, Zahra Eghbali, Elham Gholami, Tahereh Taheri, Sima Rafati   +7 more
doaj   +1 more source

Optimized Mouse BMDC Isolation and Culture under Endotoxin-Free Conditions

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021
Introduction: Dendritic cells are very important in basic studies and vaccine research, but isolation and culture of these cells face challenges due to their small number in tissues.
Atefeh Sadeghi Shermeh, Sima HAbibzadeh, Adeleh Taghikhani, Sima Rafati, Negar Seyed   +4 more
doaj  

Leishmania kinetoplast DNA contributes to parasite burden in infected macrophages: Critical role of the cGAS-STING-TBK1 signaling pathway in macrophage parasitemia

Frontiers in Immunology, 2022
Leishmania parasites harbor a unique network of circular DNA known as kinetoplast DNA (kDNA). The role of kDNA in leishmania infections is poorly understood. Herein, we show that kDNA delivery to the cytosol of Leishmania major infected THP-1 macrophages
Ismail Cem Yilmaz, Ismail Cem Yilmaz, Emre Dunuroglu, Ihsan Cihan Ayanoglu, Emre Mert Ipekoglu, Muzaffer Yildirim, Nogay Girginkardesler, Yusuf Ozbel, Seray Toz, Ahmet Ozbilgin, Gamze Aykut, Ihsan Gursel, Ihsan Gursel, Mayda Gursel, Mayda Gursel   +14 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy. [PDF]

, 2007
Leishmaniasis is a geographically widespread severe disease, with an increasing incidence of two million cases per year and 350 million people from 88 countries at risk. The causative agents are species of Leishmania, a protozoan flagellate.
Soteriadou, Ketty, Tintaya, K Wilber Quispe, Oborník, Miroslav, Lukes, Julius, Ayala, Francisco J, Kuhls, Katrin, Dujardin, Jean-Claude, Mauricio, Isabel L, Jirků, Milan, Pratlong, Francine, Miles, Michael A, Chocholová, Eva, Haralambous, Christos, Dedet, Jean-Pierre, Horák, Ales, Schönian, Gabriele, Quispe Tintaya, K. W., Soteriadou, K., Haralambous, C., Mauricio, I. L., Dujardin, J. C., Chocholova, E., Pratlong, F., Jirku, M., Obornik, M., Schönian, G., Lukes, J., Miles, M. A., Dedet, J. P., Kuhls, K., Horak, A., Ayala, F. J.   +31 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Immunity to Leishmania mexicana parasite [PDF]

, 2014
Background: Cutaneous Leishmaniasis caused by the Leishmania mexicana complex is associated with unpleasant or disfiguring lesions, for which there only limited treatment options. The life cycle of L.
Ali, KSM
core