Results 51 to 60 of about 57,558 (196)

Canine Leishmaniosis in Italy: Geospatial Trends and Incidence, a Shift in Epidemiological Approach

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Introduction Canine leishmaniosis (CanL) has shown a marked geographic expansion in Italy, progressively affecting central and northern regions previously considered non‐endemic. Laboratory‐based prevalence estimates remain informative in well‐designed surveys; however, prevalence derived from diagnostic submissions may be influenced by study ...
Federica Bruno   +16 more
wiley   +1 more source

Comparing Chemoenzymatic and Conventional Synthetic Strategies to Wall Teichoic Acid Peptidoglycan Fragments

open access: yesIsrael Journal of Chemistry, Volume 66, Issue 5, September 2026.
The Gram‐positive bacteria, Staphylococcus aureus, contain wall teichoic acid (WTA, a glycopolymer (green and yellow)) is a virulence factor in their cell wall. Synthesis of the peptidoglycan‐(PG)‐WTA conjugate (blue squares) was developed via the phospho‐donor and PG acceptor (structures at the bottom right).
Min Liu   +2 more
wiley   +1 more source

A Review of Next-Generation Plasmid Systems for the Design and Optimization of DNA Vaccines [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Vaccines are widely regarded as one of the greatest achievements of modern medicine. By substantially reducing the burden of infectious diseases, they have dramatically improved global public health and life expectancy.
Sima Habibzadeh   +3 more
doaj  

Genome-wide quantification of polycistronic transcription in Leishmania major

open access: yesmBio
Leishmania major is a human-pathogenic, obligate parasite and the etiological agent of the most prevalent, cutaneous form of leishmaniasis, which is an important neglected, tropical disease with ~1.2 million new infections per year.
Janne Grünebast   +2 more
doaj   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf   +10 more
wiley   +1 more source

Evolutionary insights into bilin biosynthesis: Functional characterization of pre‐PcyA enzymes

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Biosynthesis of the linear tetrapyrrole phycocyanobilin (PCB) by the ferredoxin‐dependent bilin reductase (FDBR) PcyA is essential for light‐harvesting and regulatory processes in diverse photosynthetic organisms, yet its evolutionary origins are not fully understood. PcyA evolved from pre‐PcyA proteins found in diverse bacteria.
Federica Frascogna   +3 more
wiley   +1 more source

Knowledge, attitudes and practices about Visceral leishmaniasis in three communes of Neiva, Huila

open access: yesRevista Habanera de Ciencias Médicas, 2023
Introduction: Visceral leishmaniasis is a zoonotic disease transmitted by vectors of the Lutzomyia genus, distributed in 98 countries, including Colombia, which can cause a serious clinical picture that, in the absence of treatment, can be fatal ...
Paola Aranzazu Garzon Polania   +4 more
doaj  

Flavopereirine—An Alkaloid Derived from Geissospermum vellosii—Presents Leishmanicidal Activity In Vitro

open access: yesMolecules, 2019
Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite.
João Victor da Silva e Silva   +11 more
doaj   +1 more source

Selective effects of Euterpe oleracea (açai) on Leishmania (Leishmania) amazonensis and Leishmania infantum

open access: yesBiomedicine & Pharmacotherapy, 2018
Leishmania (Leishmania) amazonensis and Leishmania infantum (=Leishmania chagasi) are protozoa that cause American cutaneous and visceral leishmaniasis, respectively. These diseases show a high incidence in developing countries such as Brazil. The treatments used for leishmaniasis are still limited due to their high cost and toxicity.
Bruno José Martins, Da Silva   +5 more
openaire   +2 more sources

Cellular immune response of Amblyomma sculptum and Amblyomma americanum to entomopathogenic fungi: Implications for biological tick control

open access: yesMedical and Veterinary Entomology, Volume 40, Issue 3, Page 582-594, September 2026.
Amblyomma sculptum showed a plasmatocyte‐dominant haemocyte profile. Beauveria bassiana increased plasmatocytes and reduced granulocytes, whereas Metarhizium robertsii did not cause significant changes. Amblyomma americanum showed a granulocyte‐dominant haemocyte profile. Beauveria bassiana reduced total haemocytes and granulocytes. B.
Cárita de Souza Ribeiro‐Silva   +7 more
wiley   +1 more source

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