Results 51 to 60 of about 172,432 (281)

Genetic, serological and biochemical characterization of Leishmania tropica from foci in northern Palestine and discovery of zymodeme MON-307 [PDF]

, 2012
Background Many cases of cutaneous leishmaniasis (CL) have been recorded in the Jenin District based on their clinical appearance. Here, their parasites have been characterized in depth.
A Al-Jawabreh, A Al-Jawabreh, A Al-Jawabreh, A Warburg, Abedelmajeed Nasereddin, Christophe Ravel, CL Eisenberger, CL Jaffe, DE Dobson, DF Smith, E Cupolillo, EK Saliba, EK Saliba, F Pratlong, Fouad El Baidouri, Francine Pratlong, G Anders, G Schonian, G Schonian, Gabriele Schonian, IL Mauricio, J Felsenstein, JA Rioux, JA Rioux, Jean-Pierre Dedet, JM Schwenkenbecher, K Azmi, K Azmi, Kifaya Azmi, LF Schnur, LF Schnur, LF Schnur, LF Schnur, Lionel Schnur, M Rhajaoui, M Svobodova, MZ Alam, R Maazoun, RL Jacobson, RP Soares, S Adler, S Kamhawi, S Martinez-Calvillo, SM Le Blancq, SM Le Blancq, Suheir Ereqat, Y Schlein, Y Schlein, Ziad Abdeen   +48 more
core   +3 more sources

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

Veterinary Record, EarlyView.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson, Tapan Bhattacharyya, Michael A. Miles   +2 more
wiley   +1 more source

RNA synthesis in Leishmania donovani is constitutive during stage conversion: a genome-wide PRO-seq analysis

Microbiology Spectrum
Transcription in Leishmania donovani has long been considered constitutive, as shown by nuclear run-on analyses and northern blots, with gene expression primarily regulated post-transcriptionally.
Janne Grünebast, Stephan Lorenzen, Christine Brinker, Annika Bea, Joachim Clos   +4 more
doaj   +1 more source

Shape, form, function and Leishmania pathogenicity: from textbook descriptions to biological understanding [PDF]

Open Biology, 2017
The shape and form of protozoan parasites are inextricably linked to their pathogenicity. The evolutionary pressure associated with establishing and maintaining an infection and transmission to vector or host has shaped parasite morphology.
Jack Sunter, Keith Gull
doaj   +1 more source

Relationships Between European Wildcats and Domestic Cats in an Area of Sympatry: Exploring Key Conservation Questions on Hybridization and Disease Transmission

Animal Conservation, EarlyView.
We have found evidence of behavioural barriers for both hybridization and disease transmission between European wildcats and domestic cats. This includes hierarchical interspecies exclusion enforced by wildcats, as well as sexual selection exerted by wildcat females.
Jose María Gil‐Sánchez, Elena Bertos, Mariola Sánchez‐Cerdá, Emilio Virgós, Marcos Moleón   +4 more
wiley   +1 more source

In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]

, 2014
Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
core   +2 more sources

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

Allergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter   +16 more
wiley   +1 more source

Characterization of oxidative stress in Leishmaniasis-infected or LPS-stimulated macrophages using electrochemical impedance spectroscopy [PDF]

, 2010
The physiological changes caused by external stimuli can be employed as parameters to study pathogen infection in cells and the effect of drugs. Among analytical methods, impedance is potentially useful to give insight into cellular behavior by studying ...
Coste, Agnès, Fabre, Paul-Louis, Launay, Jérôme, Nepveu, Françoise, Reybier, Karine, Ribaut, Clothilde   +5 more
core   +2 more sources

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Resolution and pro-resolving lipid mediators in Leishmania infection

Journal of Medical Microbiology and Infectious Diseases, 2019
The acute inflammatory response is the body’s natural reaction to inciting stimuli including trauma and pathogens. Well-known pro-inflammatory metabolites take control of this reaction to recruit the leukocytes into the inflamed tissue.
Negar Seyed, Sima Rafati
doaj