Results 91 to 100 of about 11,277 (209)
PLOS ONE, 2015 Chemotherapy against visceral leishmaniasis is associated with high toxicity and drug resistance. Leishmania parasites are purine auxotrophs that obtain their purines from exogenous sources. Nucleoside hydrolases release purines from nucleosides and are drug targets for anti-leishmanial drugs, absent in mammal cells.
Elisangela Oliveira Freitas +8 more
openaire +4 more sources
Brazilian Journal of Medical and Biological Research, 2007 Renal involvement in visceral leishmaniasis (VL) is very frequent but the pathogenesis of this nephropathy is poorly understood. In previous studies using dogs with VL we have detected new immunopathological elements in the glomeruli such as T cells and ...
M.G. Prianti +4 more
doaj +1 more source
Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensisto nitric oxide correlates with disease severity in Tegumentary Leishmaniasis [PDF]
, 2007 Background Nitric oxide (NO•) plays a pivotal role as a leishmanicidal agent in mouse macrophages. NO• resistant Escherichia coli and Mycobacterium tuberculosis have been associated with a severe outcome of these diseases.
Angela Giudice +63 more
core +1 more source
A Century of Epidemiological Advances in Cutaneous and Visceral Leishmaniasis in Algeria
Journal of Parasitology Research, Volume 2025, Issue 1, 2025.Leishmaniasis is a group of diseases transmitted by sandflies, affecting humans and animals, with three clinical presentations: cutaneous, mucosal, and visceral. The disease is caused by the parasite Leishmania and is a significant global health issue, with approximately two million cases annually and 350 million people at risk.
Naouel Eddaikra +3 more
wiley +1 more source
Parasites & Vectors, 2014 Background Two Leishmania major ribosomal proteins L3 (LmL3) and L5 (LmL5) have been described as protective molecules against cutaneous leishmaniasis due to infection with L.
Laura Ramirez +12 more
doaj +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2003 Un método sencillo de laboratorio reveló diferencias en el éxito de alimentación de Lutzomyia evansi, el vector de Leishmania chagasi en el norte de Colombia, cuando se alimentó sobre cinco especies de pequeños mamíferos de un foco endémico de ...
Gregory H. Adler +2 more
doaj +1 more source
Leishmania : taxonomie et phylogenèse ; applications éco-épidémiologiques [PDF]
, 1986 Un foyer de leishmaniose viscérale a été mis en évidence dans les Yungas du Département de La Paz. Le premier cas humain autochtone a pu être diagnostiqué en 1982 dans cette région. L'infection cutanée et viscérale du chien a été démontrée.
Desjeux, P. +3 more
core
Field ecology of sylvatic Rhodnius populations (Heteroptera, Triatominae): risk factors for palm tree infestation in western Ecuador. [PDF]
, 2005 Most Rhodnius species (Triatominae) are primarily associated with palm trees. They maintain enzootic Trypanosoma cruzi transmission and are responsible for human infection (causing Chagas disease) through the Neotropics. Assessing whether individual palm
Ho, A. Y. Q. +5 more
core +4 more sources
Antileishmanial Activity of Aldonamides and N-Acyl-Diamine Derivatives
The Scientific World Journal, 2008 A number of lipophilic N-acyl-diamines and aldonamides have been synthesized and tested for their in vitro antiproliferative activity against Leishmania amazonensis and L. chagasi.
Elaine S. Coimbra +7 more
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2011 INTRODUCTION: Domestic dogs are the most important reservoir in the peridomestic transmission cycle of Leishmania (Leishmania) chagasi. The genetic variability of subpopulations of this parasite circulating in dogs has not been thoroughly analyzed in ...
Carlos Eduardo Ribeiro Coutinho +4 more
doaj +1 more source