Results 81 to 90 of about 6,508 (210)

Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. [PDF]

, 2009
Genome sequencing of Leishmania species that give rise to a range of disease phenotypes in the host has revealed highly conserved gene content and synteny across the genus.
Alasdair C Ivens, Ivens, Alasdair C, Maroof, Asher, Paul M Kaye, Depledge Daniel P., Depledge, DP, Ivens, AC, Depledge, Daniel P, Maroof Asher, Aziz Naveed, Evans, KJ, Smith, Deborah F, Kaye, PM, Maroof, A, Smith, DF, Aziz, Naveed, Daniel P Depledge, Naveed Aziz, Ivens Alasdair C., Asher Maroof, Krystal J Evans, Evans Krystal J., Kaye Paul M., Aziz, N, Evans, Krystal J, Smith Deborah F., Kaye, Paul M, Deborah F Smith   +27 more
core   +1 more source

Leishmania chagasi heparin-binding protein: Cell localization and participation in L. chagasi infection

Molecular and Biochemical Parasitology, 2015
Visceral leishmaniasis is a fatal human disease caused by the intracellular protozoan parasite Leishmania chagasi that is captured by host cells in a process involving classics receptors mediated phagocytosis. The search for molecules involved in this process is important to design strategies to disease control.
Thaís Viana Fialho, Martins, Thaís Vieira, de Carvalho, Claudia Vânia Miranda, de Oliveira, Sérgio Oliveira, de Paula, Sílvia Almeida, Cardoso, Leandro Licursi, de Oliveira, Eduardo de Almeida, Marques-da-Silva   +6 more
openaire   +3 more sources

Diagnostic Challenges in Visceral Leishmaniasis in a 17‐Month‐Old Female: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Visceral leishmaniasis is an uncommon infectious disease. In this report, we present a case of VL in a 17‐month‐old child who presented with a fever and splenomegaly. After the patient failed to respond to several courses of antibiotics, a bone marrow aspirate confirmed the definitive diagnosis of VL, which was successfully treated with ...
Ahmed Sheikh Sobeh, Manal Soufan, Tasneem Sarakbi, Alaa Jaddouh, Feras Alharroush   +4 more
wiley   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Impact of leishmaniasis on public health

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
Leishmaniasis is a parasitic zoonosis caused by protozoans of the genus Leishmania transmitted by insects known as phlebotomines, which are found in wild or urban environments.
L. B Camargo, H. Langoni
doaj   +1 more source

Therapeutic Effect of Barberry (Berberis vulgaris) Root Extract on Experimental Cutaneous Leishmaniosis in a BALB/c Mouse Model

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Barberry (Berberis vulgaris) root extract shows potential in treating cutaneous leishmaniasis caused by Leishmania major. In a BALB/c mouse model, treatment significantly reduced wound size and parasite load while enhancing inflammatory markers IL‐1 and IL‐6. These results highlight barberry's therapeutic promise against leishmaniasis.
Sadegh Shirian, Morteza Norouzi Cholcheh, Saeed Habibian Dehkordi, Behnam Bakhtiari Moghadam   +3 more
wiley   +1 more source

Identification of Leishmania (Leishmania) chagasi isolated from healthy skin of symptomatic and asymptomatic dogs seropositive for leishmaniasis in the Municipality of Rio de Janeiro, Brazil

Brazilian Journal of Infectious Diseases
Euthanasia of seropositive dogs has been one of the principal measures adopted by the Program for the Control of Leishmaniasis in Brazil for many years. However, its efficacy is currently being questioned.
Maria de Fátima Madeira, Armando de Oliveira Schubach, Tânia Maria Pacheco Schubach, Cristianni Antunes Leal, Mauro Célio de Almeida Marzochi   +4 more
doaj   +1 more source

Chronic pericarditis in a naturally Leishmania (Leishmania) chagasi infected dog

Brazilian Journal of Veterinary Pathology, 2009
Visceral Leishmaniasis is an infection disease of chronic evolution caused by the protozoan Leishmania sp. The main clinical manifestations in dogs are anemia, progressive weight loss, lymphadenopathy, hepatomegaly, and cutaneous lesions. The heart involvement in visceral leishmaniasis has been rarely reported.
Bruno C. Silva, Milene A. Rachid, Fernanda G. Vieira, Maria M. Figueiredo, Guilherme R. Valle, Wagner L. Tafuri, João C. Toledo Júnior, Vitor M. Ribeiro   +7 more
openaire   +1 more source

IL‐12 and IFN‐γ in Response to Leishmania Infantum Antigens in Felines From an Endemic Area for Visceral Leishmaniasis

Parasite Immunology, Volume 47, Issue 8, August 2025.
ABSTRACT Visceral leishmaniasis is a potentially fatal zoonosis with an increasing incidence. Most infected felines present the disease in its subclinical form and demonstrate greater resistance to parasitemia than dogs. However, the role of cellular immunity in felines is still poorly understood. This study measured serum levels of interleukin (IL)‐12
João Victor Lé Lode, Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Valéria Marçal Felix de Lima   +3 more
wiley   +1 more source

Histopathological findings and detection of parasites in the eyes of dogs infected naturally with Leishmania chagasi Achados histopatológicos e detecção de parasitas nos olhos de cães infectados por Leishmania chagasi

Ciência Rural, 2010
The objective of the present study was to investigate the histopathological alterations and detection of parasites that occur in the eyes of dogs naturally infected with Leishmania chagasi.
Fábio Luiz da Cunha Brito, José Luiz Laus, Wagner Luiz Tafuri, Maria Marta Figueiredo, Valdemiro Amaro Silva Júnior, Frederico Celso Lyra Maia, Leucio Câmara Alves   +6 more
doaj