Results 81 to 90 of about 11,277 (209)

Immunological selection for Leishmania (Viannia) braziliensis antigens.

, 2002
Comparative ELISA and selective immunoblotting procedures were used in attempts to identify differential serological indicators of infection with the Leishmania (Viannia) braziliensis complex, infection with the L.
Cuba Cuba, CA, Howard, MK, Miles, MA, Ogunkolade, W   +3 more
core   +1 more source

Presence of antibodies against Leishmania chagasi in haemodialysed patients

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009
In the last decades there has been an increase in cases of visceral leishmaniasis complicating the post-transplant phase, mainly following kidney transplantation. The aim of this study was to evaluate the reactivity of haemodialysed patients using IFAT. Blood samples of 310 individuals from Natal, RN, Brazil, were collected and analysed. Data regarding
Souza, Roberto Mascarenhas, Oliveira, Isaac Braullio Maia Delfino de, Paiva, Vinícius Câmara de Sousa, Lima, Kenio Costa de, Santos, Rivaldo Pereira dos, Almeida, José Bruno de, Luz, Kleber Giovanni   +6 more
openaire   +2 more sources

Integration of Machine Learning‐QSAR and Polypharmacology in Drug Discovery for Leishmaniasis Using Natural and Repurposed Compounds

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
Leishmaniasis affects over 1 billion people worldwide, with current treatments limited by toxicity and efficacy. This study used machine learning (ML), QSAR, and polypharmacology to identify potential drug candidates, analyzing 12,072 compounds with random forest and XGBoost models.
Laís Salvador do Amaral, Amiel Artur Morais, Alexandre de Fátima Cobre, Raul Edison Luna Lazo, Dile Pontarolo Stremel, Jaqueline Carneiro, Luana Mota Ferreira, Roberto Pontarolo   +7 more
wiley   +1 more source

The carbonic anhydrase enzymes as new targets for the management of neglected tropical diseases

Archiv der Pharmazie, Volume 358, Issue 1, January 2025.
The scientific literature dealing with the identification and development of selective inhibitors of the carbonic anhydrases expressed by the protozoans Trypanosoma cruzi (T. cruzi) and Leishmania spp. is reviewed and analyzed, with the aim to sustain the validation process of new classes of drugs useful for the management of neglected tropical ...
Gioele Renzi, Federico Ladu, Fabrizio Carta, Claudiu T. Supuran   +3 more
wiley   +1 more source

Final comments on an interesting taxonomic dilemma: Leishmania infantum versus Leishmania infantum chagasi [PDF]

Memórias do Instituto Oswaldo Cruz, 2006
: donot forget the law of priorityfl (Dantas-Torres 2006) Πonthe concise review article of Lainson and Rangel (2005)has emerged as the basis of an interesting debate on theaetiological agent of American visceral leishmaniasis, i.e.,the taxonomic dilemma concerning its correct nomen-clature.
openaire   +4 more sources

Synthesis and In Vitro Antileishmanial Efficacy of Novel Ethylene Glycol Analogues of Benzothiadiazine‐1,1‐dioxide

Chemistry &Biodiversity, Volume 22, Issue 1, January 2025.
Abstract Leishmaniasis is a vector‐borne, parasitic disease affecting millions of people and animals worldwide. Current therapeutic options have proven to be ineffective in both treating the disease and preventing its spread. As a result, new drugs must be developed to effectively combat this disease.
Nadine Henning, Christina Kannigadu, Janine Aucamp, Helena D. Janse van Rensburg, Frank van der Kooy, David D. N'Da   +5 more
wiley   +1 more source

Histopathological findings and detection of parasites in the eyes of dogs infected naturally with Leishmania chagasi Achados histopatológicos e detecção de parasitas nos olhos de cães infectados por Leishmania chagasi

Ciência Rural, 2010
The objective of the present study was to investigate the histopathological alterations and detection of parasites that occur in the eyes of dogs naturally infected with Leishmania chagasi.
Fábio Luiz da Cunha Brito, José Luiz Laus, Wagner Luiz Tafuri, Maria Marta Figueiredo, Valdemiro Amaro Silva Júnior, Frederico Celso Lyra Maia, Leucio Câmara Alves   +6 more
doaj  

Identification of Leishmania (Leishmania) chagasi isolated from healthy skin of symptomatic and asymptomatic dogs seropositive for leishmaniasis in the Municipality of Rio de Janeiro, Brazil

Brazilian Journal of Infectious Diseases
Euthanasia of seropositive dogs has been one of the principal measures adopted by the Program for the Control of Leishmaniasis in Brazil for many years. However, its efficacy is currently being questioned.
Maria de Fátima Madeira, Armando de Oliveira Schubach, Tânia Maria Pacheco Schubach, Cristianni Antunes Leal, Mauro Célio de Almeida Marzochi   +4 more
doaj   +1 more source

Early suppression of lymphoproliferative response in dogs with natural infection by Leishmania infantum. [PDF]

, 1999
Dogs are the domestic reservoirs of zoonotic visceral leishmaniasis caused by Leishmania infantum. Early detection of canine infections evolving to clinically patent disease may be important to leishmaniasis control.
CIARAMELLA, PAOLO, DE LUNA R., GRADONI L., IELPO M. T. L. AMBROSIO R., MANCINO D., MOSCATIELLO V., PIANTEDOSI, DIEGO, SCALONE A., VUOTTO M. L.   +8 more
core   +1 more source

Lutzomyia migonei is a permissive vector competent for Leishmania infantum [PDF]

, 2016
BACKGROUND: Leishmania infantum is the most widespread etiological agent of visceral leishmaniasis (VL) in the world, with significant mortality rates in human cases.
Jitka Myskova, Jovana Sadlova, Katerina Pruzinova, Petr Volf, Sinval Pinto Brandão Filho, Vanessa Cristina Fitipaldi Veloso Guimarães, Vera Volfova   +6 more
core   +1 more source