Results 11 to 20 of about 11,277 (209)

The Antileishmanial Potential of C-3 Functionalized Isobenzofuranones against Leishmania (Leishmania) Infantum Chagasi [PDF]

Molecules, 2015
Leishmaniases are diseases caused by protozoan parasites of the genus Leishmania. Clinically, leishmaniases range from cutaneous to visceral forms, with estimated global incidences of 1.2 and 0.4 million cases per year, respectively. The treatment of these diseases relies on multiple parenteral injections with pentavalent antimonials or amphotericin B.
Wagner Pereira, Raphael De Souza Vasconcellos, Christiane Mariotini-Moura, Rodrigo Saar Gomes, Rafaela Firmino, Adalberto Da Silva, Abelardo Silva Júnior, Gustavo Bressan, Márcia Almeida, Luís Crocco Afonso, Róbson Teixeira, Juliana Lopes Rangel Fietto   +11 more
openaire   +5 more sources

Brain Involvement in Leishmaniasis. [PDF]

Cell Biochem Funct
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Freitas CS, Coelho EAF, Christodoulides M.   +2 more
europepmc   +2 more sources

Assessment of Leishmania exposure in blood donors from a non-endemic urban area: A study in São Paulo. [PDF]

Vox Sang
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
de Lima IS, Ferreira SC, Nishiya AS, Kesper N, Ferreira JE, de Castro Gomes CM, Derriga J, Dantas KC, Polato SPG, Salles NA, Lindoso JAL, Fanciani T, de Almeida-Neto C, Rocha V, Mendrone A.   +14 more
europepmc   +2 more sources

Cutaneous Leishmaniasis Mimicking a Nasal Tumor: A Case Report. [PDF]

Case Rep Infect Dis
Leishmaniasis is a disease caused by Leishmania protozoa that is transmitted to the patient by sand flies. Depending on the Leishmania species, the disease can present with cutaneous, mucosal, or multiorgan involvement. Cutaneous leishmaniasis can present with diverse clinical manifestations mimicking other diseases.
Hekmat M, Namazi MR, Najibi AH, Shirazi Yeganeh B, Fazelzadeh Haghighi N.   +4 more
europepmc   +2 more sources

Heterogeneities in leishmania infantum infection : using skin parasite burdens to identify highly infectious dogs [PDF]

, 2013
Background: The relationships between heterogeneities in host infection and infectiousness (transmission to arthropod vectors) can provide important insights for disease management.
A Mohammadiha, A Mohammadiha, ANS Maia-Elkhoury, AP da Costa-Val, AP Galvani, BL Travi, BLA Vercosa, C Carson, C Fraser, C Mary, C Mary, CDL Oliveira, CHN Costa, CHN Costa, Connor Carson, DJ Shaw, DW Dowdy, EM Michalsky, GA Soper, IFGd Amorim, JO Lloyd-Smith, KJ Esch, KTD Eames, L Dipineto, L Manna, L Manna, L Matthews, Leo Calvo-Bado, LHdS Marques, LLH Lau, Lourdes M. Garcez, LVR Lima, M Chase-Topping, Marleen Boelaert, MEJ Woolhouse, O Courtenay, O Courtenay, O Courtenay, O Francino, Orin Courtenay, PF Quaresma, R Lainson, R Molina, R Molina, R Verin, RA Stein, RB Gomes, RC Giunchetti, RJ Quinnell, RJ Quinnell, RJ Quinnell, RJ Quinnell, RM Anderson, RM May, Rupert J. Quinnell, S Bossolasco, SdA Ferreira   +56 more
core   +12 more sources

Native rodent species are unlikely sources of infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru. [PDF]

, 2014
An estimated 2.3 million disability-adjusted life years are lost globally from leishmaniasis. In Peru's Amazon region, the department of Madre de Dios (MDD) rises above the rest of the country in terms of the annual incidence rates of human leishmaniasis.
Conrad, Patricia A, De Los Santos, Maxy, Ghersi, Bruno M, Lescano, Andres G, Mazet, Jonna AK, Montgomery, Joel M, Razuri, Hugo, Shender, Lisa A   +7 more
core   +9 more sources

Leishmania (infantum) chagasi in canine urinary sediment [PDF]

Revista Brasileira de Parasitologia Veterinária, 2015
Canine visceral leishmaniasis (CVL) is difficult to diagnosis, mainly due to the presence of asymptomatic animals, the diversity of clinical symptoms and the difficulty in obtaining diagnostic evidence of high sensitivity and specificity. The purpose of this study was to diagnose CVL in urinary sediment of 70 dogs of different breeds, sexes and ages ...
Mendonça, Ivete Lopes de, Batista, Joilson Ferreira, Alves, Leucio Camara   +2 more
openaire   +4 more sources

Evidência de transmissão de leishmaniose visceral por Lutzomyia cruzi no município de Jaciara, Estado de Mato Grosso, Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUÇÃO: O município de Jaciara foi classificado em 2003, como área de transmissão de leishmaniose visceral em situação de surto. O trabalho objetivou determinar evidência de transmissão de Leishmania (Leishmania) infantum chagasi por Lutzomyia cruzi ...
Nanci Akemi Missawa, Márcia Aurélia Esser Veloso, Giovana Belem Moreira Lima Maciel, Érika Monteiro Michalsky, Edelberto Santos Dias   +4 more
doaj   +1 more source

Tissue Cytokine Responses in Canine Visceral Leishmaniasis [PDF]

, 2001
To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine mRNA levels were measured in bone marrow aspirates from 27 naturally infected dogs from Brazil and were compared with those from 5 uninfected control ...
Courtenay, O., Day, M.J., Dye, C., Garcez, L.M., Kaye, P.M., Quinnell, R.J., Shaw, M.-A.   +6 more
core   +2 more sources

Identificação de espécies de Leishmania isoladas de casos humanos em Mato Grosso do Sul por meio da reação em cadeia da polimerase Identification of Leishmania species isolated in human cases in Mato Grosso do Sul, by means of the polymerase chain reaction

Revista da Sociedade Brasileira de Medicina Tropical, 2009
As leishmanioses são zoonoses endêmicas em Mato Grosso do Sul e têm por agentes etiológicos nessa região Leishmania (Leishmania) chagasi, Leishmania (Leishmania) amazonensis e Leishmania (Viannia) braziliensis.
Manoel Sebastião da Costa Lima Junior, Renato Andreotti, Maria Elizabeth Moraes Cavalheiros Dorval, Elisa Teruya Oshiro, Alessandra Gutierrez de Oliveira, Maria de Fatima Cepa Matos   +5 more
doaj   +1 more source