A sensitive flow cytometric methodology for studying the binding of to canine peritoneal macrophages [PDF]
The Leishmania promastigote-macrophage interaction occurs through the association of multiple receptors on the biological membrane surfaces. The success of the parasite infection is dramatically dependent on this early interaction in the vertebrate host,
Ricardo Gonçalves +49 more
core +3 more sources
Reproduction of Leishmania (Leishmania ) infantum chagasi in conditioned cell culture growth medium [PDF]
Leishmanias can be produced by inoculation in conditioned McCoy cell culture growth medium (CGM). Leishmania (Leishmania) infantum chagasi (100 parasites) grown in NNN medium was inoculated in 2.5 mL CGM, kept in plates (24 wells) and its multiplication was observed for five days (120 hours).
Nogueira, Yeda L., Galati, Eunice A.B.
openaire +4 more sources
Indirect immunofluorescence is the method recommended for the diagnosis of visceral leishmanisis in dogs, however, the accuracy of this technique is low and its use on a large scale is limited.
Flávia Coelho Ribeiro +8 more
doaj +1 more source
IL-12 and IFN-γ in Response to Leishmania Infantum Antigens in Felines From an Endemic Area for Visceral Leishmaniasis. [PDF]
ABSTRACT Visceral leishmaniasis is a potentially fatal zoonosis with an increasing incidence. Most infected felines present the disease in its subclinical form and demonstrate greater resistance to parasitemia than dogs. However, the role of cellular immunity in felines is still poorly understood. This study measured serum levels of interleukin (IL)‐12
Lode JVL +3 more
europepmc +2 more sources
Genetic Complementation to Identify DNA Elements That Influence Complement Resistance in Leishmania chagasi [PDF]
Past studies showed that Leishmania spp. promastigotes exhibit differential sensitivity to complement mediated lysis (CML) during development in vitro and in vivo.
Beetham, Jeffrey +3 more
core +3 more sources
Leishmaniose visceral canina e doença de Chagas em cães de Araguaína, Tocantins [PDF]
The present study analyzed serum samples from 111 male and female dogs of various ages from the municipality\ud of Araguaína in the State of Tocantins, Brazil. Serological diagnosis of canine visceral leishmaniasis (CVL) was initially\ud performed at the
Ekman, Luciana Regina Meireles Jaguaribe +4 more
core +4 more sources
Outbreak of canine visceral leishmaniasis in Barra Mansa, State of Rio de Janeiro
Introduction In Brazil, visceral leishmaniasis (VL) has spread to various regions. This study reports canine cases of VL in Barra Mansa, where human VL cases were recently reported.
Cintia Xavier de Mello +5 more
doaj +1 more source
SUMMARY American tegumentary leishmaniasis (ATL) is an infectious disease caused by protozoa of the genus Leishmania, and transmitted by sandflies. In the state of Rio de Janeiro, almost all of the cases of American tegumentary leishmaniasis (ATL) are ...
Marcelo Rosandiski LYRA +6 more
doaj +1 more source
Cross-protective immunity to Leishmania amazonensis is mediated by CD4+and CD8+epitopes of Leishmania donovani nucleoside hydrolase terminal domains [PDF]
The nucleoside hydrolase (NH) of Leishmania donovani (NH36) is a phylogenetic marker of high homology among Leishmania parasites. in mice and dog vaccination, NH36 induces a CD4+ T cell-driven protective response against Leishmania chagasi infection ...
Alexandre eMorrot +9 more
core +4 more sources
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik +5 more
wiley +1 more source

