Results 131 to 140 of about 13,658 (180)

The emergence of Leishmania major and Leishmania donovani in southern Turkey

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2014
In southern Turkey, Leishmania tropica and L. infantum are both the causative agents of cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL), respectively. However, L. major and L. donovani were known to exist after the influx of Syrian refugees.Between the years of July 2003 and July 2013, a total of 167 smears and 113 bone marrow samples were
Fadime Eroglu, Soner Uzun, Derya Alabaz   +2 more
exaly   +3 more sources

Leishmania donovani leishmaniasis in Cyprus

The Lancet Infectious Diseases, 2008
1recently discussed the emergence of Leishmania donovani in Cyprus. We would like to provide some additional data regarding possible vector species that might have caused the disease outbreak on this island. The presence of L donovani was reported in the eastern Mediterranean basin about 10 years ago in the vicinity of Kassab, northern Syria, when an ...
Maria, Antoniou, Christos, Haralambous, Apostolos, Mazeris, Francine, Pratlong, Jean-Pierre, Dedet, Ketty, Soteriadou   +5 more
openaire   +2 more sources

Purine metabolism in Leishmania donovani and Leishmania braziliensis

Biochimica et Biophysica Acta (BBA) - General Subjects, 1978
We have studied purine metabolism in the culture forms of Leishmania donovani and Leishmania braziliensis. These organisms are incapable of synthesizing purines de novo from glycine, serine, or formate and require an exogenous purine for growth. This requirement is better satisfied by adenosine or hypoxanthine than by guanosine.
J J, Marr, R L, Berens, D J, Nelson
openaire   +2 more sources

The Ultrastructure of Leishmania donovani

The Journal of Parasitology, 1956
The structure of the intracellular form of Leishmania donovani as seen by the light microscope consists of a nucleus and usually a rod-like kinetoplast (Wenyon, 1926) within a homogeneous mass of cytoplasm, while the extracellular or culture form has, in addition to these structures, an anterior flagellum.
openaire   +2 more sources

Characterization of strains of Leishmania donovani

Experimental Parasitology, 1966
Abstract Even with the most standardized procedures yet available for in vivo trials, the intrastrain variations in the course of infection of Leishmania donovani in the hamster permit no easy assessment of variations among those tested by us from several parts of the world.
openaire   +2 more sources

Mechanism of interaction of sitamaquine with Leishmania donovani

Journal of Antimicrobial Chemotherapy, 2010
This study focuses on the mechanism of interaction of sitamaquine with Leishmania donovani membranes, and its accumulation within the parasites.A biomimetic model of the outer layer of a Leishmania plasma membrane was used to examine the interactions of sitamaquine with lipids. The plasma membranes of L.
E S, Coimbra, D, Libong, S, Cojean, M, Saint-Pierre-Chazalet, A, Solgadi, L, Le Moyec, A M, Duenas-Romero, P, Chaminade, P M, Loiseau   +8 more
openaire   +2 more sources

Cell surface lipophosphoglycan of Leishmania donovani

Molecular and Biochemical Parasitology, 1987
Based on a galactose oxidase/NaB[3H]4 technique of radiolabeling macromolecules, the major glycoconjugate (lipophosphoglycan) of Leishmania donovani promastigotes was determined to be located on the cell surface. Incorporated radioactivity was analyzed by gel filtration on Sephadex G-100, chromatography on ricin agglutinin-coupled agarose, and lability
D L, King, Y D, Chang, S J, Turco
openaire   +2 more sources

Lipophosphoglycan Antigen Shedding By Leishmania Donovani

Journal of Eukaryotic Microbiology, 1993
ABSTRACT. The biochemical characterizations of lipophosphoglycans from various Leishmania species reported by other workers may or may not contain several types of lipophosphoglycan molecules. This is the first report in which a specific lipophosphoglycan has been defined by both its antigenie and electrophoretic properties. Furthermore, a purification
E S, Kaneshiro, M A, Wyder
openaire   +2 more sources

Uptake and turnover of glucose in Leishmania donovani

Molecular and Biochemical Parasitology, 1993
Glucose uptake and metabolism by Leishmania donovani promastigotes was studied using D-[14C]glucose in combination with the silicone oil centrifugation technique on organisms preadapted to different growth rates and glucose availability in the chemostat. The uptake step was differentiated from the subsequent metabolism by separation in time rather than
B H, Ter Kuile, F R, Opperdoes
openaire   +2 more sources

Oxidation of Leucine by Leishmania donovani

The Journal of Protozoology, 1991
ABSTRACT. The metabolism of leucine by Leishmania donovani was investigated. Washed promastigotes were incubated with (1‐14C]‐or [U‐14C]leucine or [1 ‐14C]α‐ketoisocaproate (KIC) and 14C02 release was measured. The amount of KIC‐derived acetyl‐CoA oxidized in the citric acid cycle was computed. Promastigotes from mid‐stationary phase cultures oxidized
openaire   +2 more sources