Results 111 to 120 of about 31,150 (219)
Hamster inoculated intraperitoneally with 1 x 10(7) parasites of L. donovani and L. major-like of the New World were studied in groups of 15, 30, 60 and 90 days of infection. The parasite load and density showed progressive increase with the evolution of
M. I. S. Duarte +3 more
doaj +1 more source
Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs [PDF]
Leishmaniasis is a serious medical issue in many countries around the World, but it remains largely neglected in terms of research investment for developing new control and treatment measures.
Aguado, Begoña +10 more
core +2 more sources
The spectrum and efficacy of available antileishmanial drugs is limited. In the present work we evaluated in vitro the antiproliferative activity of 11 compounds based on tetradentate polyamines compounds against three Leishmania species (L. braziliensis,
Kristína Urbanová +10 more
doaj +1 more source
The use of K39 test in the diagnosis of visceral leishmaniasis [PDF]
From time to time patients admitted with fever of unknown origin prove to be a diagnostic dilemma. While textbooks describe typical symptoms and signs, and also diagnostic tests, these are not always helpful.
Sciberras, Robert
core
Metabolism of formycin B by Leishmania amastigotes in vitro. Comparative metabolism in infected and uninfected human macrophages. [PDF]
Formycin B is metabolized by cutaneous Leishmania amastigotes within cultured human macrophages to give formycin B 5'-monophosphate and formycin A 5'-mono-, di-, and triphosphates. Formycin A is also incorporated into RNA.
Berman, JD, Rainey, P, Santi, DV
core
Leishmania donovani methionine adenosyltransferase
This research was supported by Comisión Interministerial de Ciencia y Tecnología (grants PM98/0036 and PB96/0159), Junta de Castilla y León (grants LE05/01 and LE06/02) and Fondo de Investigación Sanitaria del Ministerio de Sanidad y Consumo (grant FIS 01/1077).
Pérez-Pertejo, Yolanda +2 more
openaire +1 more source
Molecular variation in Leishmania parasites from sandflies species of a zoonotic cutaneous leishmaniasis in northeast of Iran [PDF]
Background & objectives: In the well-known zoonotic cutaneous leishmaniasis (ZCL) focus in Turkmen Sahara, border of Iran and Turkmenistan, ZCL has increased among humans in the past five years.
Parvizi, P. +4 more
core
Leishmaniasis is a neglected disease with a global spread that affects both domestic and wild animals in addition to people. Leishmania donovani is the suspected anthroponotic cause of visceral leishmaniasis (VL) in India, where it is an endemic disease.
Gajala Deethamvali Ghouse Peer +10 more
doaj +1 more source

