Results 161 to 170 of about 69,891 (211)

Leishmania donovani leishmaniasis in Cyprus

The Lancet Infectious Diseases, 2008
1recently discussed the emergence of Leishmania donovani in Cyprus. We would like to provide some additional data regarding possible vector species that might have caused the disease outbreak on this island. The presence of L donovani was reported in the eastern Mediterranean basin about 10 years ago in the vicinity of Kassab, northern Syria, when an ...
Maria, Antoniou, Christos, Haralambous, Apostolos, Mazeris, Francine, Pratlong, Jean-Pierre, Dedet, Ketty, Soteriadou   +5 more
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Purine metabolism in Leishmania donovani and Leishmania braziliensis

Biochimica et Biophysica Acta (BBA) - General Subjects, 1978
We have studied purine metabolism in the culture forms of Leishmania donovani and Leishmania braziliensis. These organisms are incapable of synthesizing purines de novo from glycine, serine, or formate and require an exogenous purine for growth. This requirement is better satisfied by adenosine or hypoxanthine than by guanosine.
J J, Marr, R L, Berens, D J, Nelson
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The Ultrastructure of Leishmania donovani

The Journal of Parasitology, 1956
The structure of the intracellular form of Leishmania donovani as seen by the light microscope consists of a nucleus and usually a rod-like kinetoplast (Wenyon, 1926) within a homogeneous mass of cytoplasm, while the extracellular or culture form has, in addition to these structures, an anterior flagellum.
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Characterization of strains of Leishmania donovani

Experimental Parasitology, 1966
Abstract Even with the most standardized procedures yet available for in vivo trials, the intrastrain variations in the course of infection of Leishmania donovani in the hamster permit no easy assessment of variations among those tested by us from several parts of the world.
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Mechanism of interaction of sitamaquine with Leishmania donovani

Journal of Antimicrobial Chemotherapy, 2010
This study focuses on the mechanism of interaction of sitamaquine with Leishmania donovani membranes, and its accumulation within the parasites.A biomimetic model of the outer layer of a Leishmania plasma membrane was used to examine the interactions of sitamaquine with lipids. The plasma membranes of L.
E S, Coimbra, D, Libong, S, Cojean, M, Saint-Pierre-Chazalet, A, Solgadi, L, Le Moyec, A M, Duenas-Romero, P, Chaminade, P M, Loiseau   +8 more
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Glucose transport in Leishmania donovani promastigotes

Molecular and Biochemical Parasitology, 1984
Mid-log phase Leishmania donovani promastigotes accumulated 2-deoxy-D-glucose (2-DOG) via a carrier mediated transport system, maintaining an apparent Km of 24.4 microM and a Vmax of 3.12 nmol mg-1 protein min-1. D-Glucose but not L-glucose competitively inhibited the 2-DOG transport with an apparent Ki of 18.7 microM.
D, Zilberstein, D M, Dwyer
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Stages in the life-cycle of Leishmania donovani

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1960
Abstract 1. 1) A technique for observing the phenomena associated with the first stages of infection of cells by flagellates of Leishmania donovani is described. In our experience flagellates enter only monocytes and there is a mutual attraction. They enter body first, and once inside the cell move freely, flagellum first.
R J, PULVERTAFT, G F, HOYLE
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Oxidation of Leucine by Leishmania donovani

The Journal of Protozoology, 1991
ABSTRACT. The metabolism of leucine by Leishmania donovani was investigated. Washed promastigotes were incubated with (1‐14C]‐or [U‐14C]leucine or [1 ‐14C]α‐ketoisocaproate (KIC) and 14C02 release was measured. The amount of KIC‐derived acetyl‐CoA oxidized in the citric acid cycle was computed. Promastigotes from mid‐stationary phase cultures oxidized
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Solution structure of the lipophosphoglycan of Leishmania donovani

Biochemistry, 1992
The three-dimensional solution structure of the repeating -PO4-6Gal beta 1-4Man alpha 1- disaccharide fragment of the lipophosphoglycan (LPG) derived from Leishmania donovani has been determined by use of a combination of homo- and heteronuclear NMR spin coupling constant measurements together with restrained molecular mechanical minimization and ...
S W, Homans, A, Mehlert, S J, Turco
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Cell surface lipophosphoglycan of Leishmania donovani

Molecular and Biochemical Parasitology, 1987
Based on a galactose oxidase/NaB[3H]4 technique of radiolabeling macromolecules, the major glycoconjugate (lipophosphoglycan) of Leishmania donovani promastigotes was determined to be located on the cell surface. Incorporated radioactivity was analyzed by gel filtration on Sephadex G-100, chromatography on ricin agglutinin-coupled agarose, and lability
D L, King, Y D, Chang, S J, Turco
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