Results 101 to 110 of about 78,367 (315)

Seasonal Dynamics of Phlebotomine Sand Fly Species Proven Vectors of Mediterranean Leishmaniasis Caused by Leishmania infantum

open access: yesPLoS Neglected Tropical Diseases, 2016
Background The recent geographical expansion of phlebotomine vectors of Leishmania infantum in the Mediterranean subregion has been attributed to ongoing climate changes.
B. Alten   +35 more
semanticscholar   +1 more source

Automated identification of flagella from videomicroscopy via the medial axis transform [PDF]

open access: yes, 2018
Ubiquitous in eukaryotic organisms, the flagellum is a well-studied organelle that is well-known to be responsible for motility in a variety of organisms. Commonly necessitated in their study is the capability to image and subsequently track the movement of one or more flagella using videomicroscopy, requiring digital isolation and location of the ...
arxiv   +1 more source

Current Distribution of Selected Vector‐borne Diseases in Domestic Dogs From Bucharest, Romania

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
Serological testing of 317 dogs in Bucharest (2020‐2024) revealed an overall Canine vector‐borne diseases (CVBD) seroprevalence of 8.8%, with Dirofilaria immitis (12.62%) being the most common. Shelter and older dogs had higher infection rates. Climate change and vector expansion may influence pathogen spread, underscoring the need for enhanced ...
Ioana Sandu   +3 more
wiley   +1 more source

Seroepidemiology of Leishmania infantum in rural dogs in Golestan province, Iran

open access: yesMedical Laboratory Journal, 2015
Background and Objective: Dogs have been introduced as a major reservoir of Leishmania infantum.  Concerning the increased sporadic reports of humeral visceral leishmaniasis in Golestan province, we aimed to study seroepidemiology of leishmania infantum ...
Namroodi, S, Saberi, M
doaj  

Canine antibody response to Phlebotomus perniciosus bites negatively correlates with the risk of Leishmania infantum transmission. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
BACKGROUND: Phlebotomine sand flies are blood-sucking insects that can transmit Leishmania parasites. Hosts bitten by sand flies develop an immune response against sand fly salivary antigens.
Michaela Vlkova   +7 more
doaj   +1 more source

Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy.

open access: yes, 2007
Leishmaniasis is a geographically widespread severe disease, with an increasing incidence of two million cases per year and 350 million people from 88 countries at risk. The causative agents are species of Leishmania, a protozoan flagellate.
Ayala, Francisco J   +15 more
core   +2 more sources

Use of miltefosine to treat canine visceral leishmaniasis caused by Leishmania infantum in Brazil

open access: yesParasites & Vectors, 2019
Visceral leishmaniasis (VL) is an infectious disease with a variety of clinical signs. The main form of parasite transmission to humans and other mammalian hosts is through the bite of infected arthropod females with Lutzomyia longipalpis serving as the ...
Fabio dos Santos Nogueira   +7 more
semanticscholar   +1 more source

Integration of Machine Learning‐QSAR and Polypharmacology in Drug Discovery for Leishmaniasis Using Natural and Repurposed Compounds

open access: yesChemistrySelect, Volume 10, Issue 21, June 4, 2025.
Leishmaniasis affects over 1 billion people worldwide, with current treatments limited by toxicity and efficacy. This study used machine learning (ML), QSAR, and polypharmacology to identify potential drug candidates, analyzing 12,072 compounds with random forest and XGBoost models.
Laís Salvador do Amaral   +7 more
wiley   +1 more source

Biomarkers Associated With Leishmania infantum Exposure, Infection, and Disease in Dogs

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Canine leishmaniosis (CanL) is a vector-borne disease caused by the protozoan Leishmania (Leishmania) infantum species [syn. L. (L.) infantum chagasi species in the Americas] which is transmitted by the bite of a female phlebotomine sand fly.
C. Maia, L. Campino
semanticscholar   +1 more source

Profiling Serine Hydrolases in the Leishmania Host–Pathogen Interactome Using Cell‐Permeable Activity‐Based Fluorophosphonate Probes

open access: yesChemBioChem, Volume 26, Issue 10, May 27, 2025.
Leishmaniasis poses a global health challenge with limited treatment options and rising drug resistance. Activity‐based protein profiling using fluorophosphonate probes is employed to profile serine hydrolases, key virulence factors in Leishmania mexicana.
Jaime A. Isern   +7 more
wiley   +1 more source

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