Results 101 to 110 of about 79,414 (305)

Molecular detection and characterization of Leishmania infantum in free-ranging Egyptian mongoose (Herpestes ichneumon)

International Journal for Parasitology: Parasites and Wildlife, 2020
Wild mammals are susceptible to infection by Leishmania parasites. Although canine leishmaniasis is widely distributed in mainland Portugal, the sylvatic cycle of the parasite remains poorly understood. In this study, the occurrence of L.
Jacinto Gomes, Hugo Rocha, Carina Carvalho, Victor Bandeira, Carlos Fonseca, Luís Miguel Rosalino, Mónica V. Cunha   +6 more
doaj  

Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Inhibition of Leishmania arginase leads to a decrease in parasite growth and infectivity and thus represents an attractive therapeutic strategy. We evaluated the inhibitory potential of selected naturally occurring phenolic substances on Leishmania ...
Andreza R Garcia, D. Oliveira, Ana Claudia F Amaral, J. B. Jesus, Ana Carolina Rennó Sodero, Alessandra M T Souza, C. Supuran, Alane Beatriz Vermelho, I. A. Rodrigues, A. Pinheiro   +9 more
semanticscholar   +1 more source

The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil [PDF]

, 1997
We estimate the incidence rate, serological conversion rate and basic case reproduction number (R0) of Leishmania infantum from a cohort study of 126 domestic dogs exposed to natural infection rates over 2 years on Marajó Island, Pará State, Brazil.
Courtenay, O., Dye, C., Garcez, L.M., Quinnell, R.J.   +3 more
core   +1 more source

Neurolymphomatosis of T‐Cell Origin in a Dog

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT A 10‐year‐old mixed‐breed dog was presented with progressive neurological deficits suggestive of polyneuropathy. CT and MRI revealed no relevant abnormalities, whereas the CSF analysis showed a marked lymphocytic pleocytosis, immunocytochemically classified as T‐cell lymphoma.
Marie‐Kerstin Müller, Michaela Irmscher, Nadja Goldbach, Alexander F. H. Haake, Olivia Kershaw, Penelope A. Baloi   +5 more
wiley   +1 more source

Integration of Machine Learning‐QSAR and Polypharmacology in Drug Discovery for Leishmaniasis Using Natural and Repurposed Compounds

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
Leishmaniasis affects over 1 billion people worldwide, with current treatments limited by toxicity and efficacy. This study used machine learning (ML), QSAR, and polypharmacology to identify potential drug candidates, analyzing 12,072 compounds with random forest and XGBoost models.
Laís Salvador do Amaral, Amiel Artur Morais, Alexandre de Fátima Cobre, Raul Edison Luna Lazo, Dile Pontarolo Stremel, Jaqueline Carneiro, Luana Mota Ferreira, Roberto Pontarolo   +7 more
wiley   +1 more source

Geographic distribution and spatial analysis of Leishmania infantum infection in domestic and wild animal reservoir hosts of zoonotic visceral leishmaniasis in Iran: A systematic review

Journal of Vector Borne Diseases, 2018
Visceral leishmaniasis (VL) is an important parasitic disease which is endemic in different parts of Iran; and domestic and wild canines are principal reservoir hosts of the disease.
M. Mohebali, E. Moradi-Asl, Y. Rassi
semanticscholar   +1 more source

Mating disruption of citrus leafminer mediated by a noncompetitive mechanism at a remarkably low pheromone release rate.

, 2008
The citrus leafminer, Phyllocnistis citrella Stainton (Lepidoptera: Gracillariidae), is a worldwide pest of citrus. A season-long investigation was conducted that evaluated mating disruption for this pest. Effective disruption of the male P.
Miller, JR, Rogers, ME, Stelinski, LL
core   +1 more source

Leishmaniasis in Patients With Inflammatory Bowel Disease: A National Multicenter Study of GETECCU

United European Gastroenterology Journal, Volume 13, Issue 5, Page 674-684, June 2025.
ABSTRACT Background Leishmaniasis (LI) is a vector‐borne illness caused by a protozoan of the genus Leishmania. Data on the features of LI in patients with inflammatory bowel disease (IBD) are scarce. Aim To describe the characteristics of patients with IBD who present with leishmaniasis, infection outcomes and the risk factors associated with ...
L Madero‐Velázquez, A Mínguez, L Mayorga, JJ Ramírez, N Moreno, C Amorós, MA Nieto, R Mena, JM Benítez, L Gimeno‐Pitarch, N Maroto, C Suria, F Rodríguez‐Moranta, I Ordás, L Ruiz, MA García‐Brenes, A Martín‐Cardona, C Rubín de Célix, K Cárdenas, D Ginard, L Medina, N Pedrero, R Plaza, R Salmoral, TJ Martínez‐Pérez, V Algara, E Merino, Y Zabana, A Gutiérrez, on behalf of Young Group of GETECCU   +29 more
wiley   +1 more source

Assessment of Leishmania infantum infection in equine populations in a canine visceral leishmaniosis transmission area

BMC Veterinary Research, 2019
BackgroundLeishmaniosis, zoonosis that produces significant public health impacts, is caused by Leishmania infantum. Canines are the main domestic reservoir and, besides humans, other species of mammals could be infected when living in endemic areas.
T. A. Escobar, G. Dowich, Thália Pacheco Dos Santos, L. Zuravski, C. A. Duarte, I. Lübeck, V. Manfredini   +6 more
semanticscholar   +1 more source

Direct-acting antivirals and visceral leishmaniasis: A case report [PDF]

, 2019
Background: Visceral leishmaniasis is a vector-borne parasitic disease caused by protozoa belonging to the genus Leishmania. The clinical presentation of visceral leishmaniasis strictly depends on the host immunocompetency, whereas depressive conditions ...
Cascio, A., Cervo, A., Colomba, C., Di Carlo, P., Firenze, A., Saporito, L., Tolomeo, M., Trizzino, M.   +7 more
core   +1 more source