Results 111 to 120 of about 81,598 (300)

Vaccination with Leishmania infantum Acidic Ribosomal P0 but Not with Nucleosomal Histones Proteins Controls Leishmania infantum Infection in Hamsters

PLOS Neglected Tropical Diseases, 2015
Several intracellular Leishmania antigens have been identified in order to find a potential vaccine capable of conferring long lasting protection against Leishmania infection. Histones and Acid Ribosomal proteins are already known to induce an effective immune response and have successfully been tested in the cutaneous leishmaniasis mouse model.
Lais Pereira, Melissa Abbehusen, Clarissa Teixeira, Jurema Cunha, Ivan P Nascimento, Ivan P Nascimento, Kyioshi Fukutani, Washington dos-Santos, Aldina Barral, Camila Indiani de Oliveira, Manoel Barral-Netto, Manoel Soto, Cláudia Ida Brodskyn   +12 more
openaire   +6 more sources

Complete Resolution of Cutaneous Leishmaniasis With a Novel Topical Combination Therapy: A Case Series

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Cutaneous leishmaniasis (CL) remains a therapeutic challenge in endemic regions, with 600,000–1 million new cases annually facing limited treatment options. We present a case series evaluating an innovative topical combination therapy for acute‐phase CL in Shiraz, Iran.
Hoda Haghshenas, Aref Ghanaatpisheh, Mohammad Darayesh, Elaheh Entezar Almahdi   +3 more
wiley   +1 more source

Zoonotic Parasites in Marmosets (Callithrix Spp.) From Southern Brazil: Insights From a One Health Perspective

Journal of Medical Primatology, Volume 54, Issue 5, October 2025.
ABSTRACT Background Currently, six species of Callithrix are frequently observed in anthropized and degraded environments in different regions of Brazil. This occupation favors interactions with humans and increases the risk of infection by parasites with zoonotic potential.
Maysa Emanuely dos Santos, Matheus Azambuja, Denilton Vidolin, Rosimeire Nunes de Oliveira   +3 more
wiley   +1 more source

A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis [PDF]

Previous studies demonstrated safety, immunogenicity and efficacy of DNA/modified vaccinia virus Ankara (MVA) prime/boost vaccines expressing tryparedoxin peroxidase (TRYP) and Leishmania homologue of the mammalian receptor for activated C kinase (LACK ...
Alcami, Antonio, Antoniou, Maria, Begoña Ruiz-Argüello, Maria, Blackwell, Jenefer M., Carson, Connor, Christodoulou, Vasiliki, Courtenay, Orin, Messaritakis, Ippokratis   +7 more
core   +1 more source

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +3 more sources

Natural Resistance of Leishmania infantum to Miltefosine Contributes to the Low Efficacy in the Treatment of Visceral Leishmaniasis in Brazil

American Journal of Tropical Medicine and Hygiene, 2019
. In India, visceral leishmaniasis (VL) caused by Leishmania donovani has been successfully treated with miltefosine with a cure rate of > 90%. To assess the efficacy and safety of oral miltefosine against Brazilian VL, which is caused by Leishmania ...
J. Carnielli, Renata Monti-Rocha, D. L. Costa, Aretha Molina Sesana, L. Pansini, Marcela Segatto, J. Mottram, C. Costa, S. G. Carvalho, R. Dietze   +9 more
semanticscholar   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Geographic distribution and spatial analysis of Leishmania infantum infection in domestic and wild animal reservoir hosts of zoonotic visceral leishmaniasis in Iran: A systematic review

Journal of Vector Borne Diseases, 2018
Visceral leishmaniasis (VL) is an important parasitic disease which is endemic in different parts of Iran; and domestic and wild canines are principal reservoir hosts of the disease.
M. Mohebali, E. Moradi-Asl, Y. Rassi
semanticscholar   +1 more source

Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) represents the most common form of leishmaniasis. It imposes a significant medical burden due to long‐lasting ulcers and disfiguring scars, underscoring the need for comprehensive CL control strategies, particularly in endemic regions.
Bahareh Abtahi‐Naeini, Seyed Naser Emadi, Zabihollah Shahmoradi, Mahsa Pourmahdi‐Boroujeni, Ali Saffaei, Fereshte Rastegarnasab   +5 more
wiley   +1 more source

Prevalence and Sequence Analysis of Vector‐Borne Zoonotic Diseases in Stray Cats in Istanbul

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Istanbul, the largest metropolis in Türkiye, is home to a notable population of stray cats. While cats enrich the city's culture, they can also transmit various diseases, posing diagnostic challenges for clinicians. This study aimed to detect infections in stray cats using PCR and sequencing to identify Ehrlichia, Anaplasma, Bartonella, Hepatozoon ...
Tuba Yazicioglu, Handan Cetinkaya
wiley   +1 more source