PLoS Neglected Tropical Diseases, 2020 Leishmaniasis constitutes the 9th largest disease burden among all infectious diseases. Control of this disease is based on a short list of chemotherapeutic agents headed by pentavalent antimonials, followed by miltefosine and amphotericin B; drugs that ...
Noélie Douanne +4 more
semanticscholar +1 more source
Final comments on an interesting taxonomic dilemma: Leishmania infantum versus Leishmania infantum chagasi [PDF]
Memórias do Instituto Oswaldo Cruz, 2006 : donot forget the law of priorityfl (Dantas-Torres 2006) Œ onthe concise review article of Lainson and Rangel (2005)has emerged as the basis of an interesting debate on theaetiological agent of American visceral leishmaniasis, i.e.,the taxonomic dilemma concerning its correct nomen-clature.
openaire +5 more sources
Manifestations of paediatric Leishmania infantum infections in Malta [PDF]
Travel Medicine and Infectious Disease, 2011 Leishmania infantum is endemic in the Maltese archipelago, a group of islands in the Mediterranean which are visited frequently by tourists from Northern European countries. The burden of leishmaniasis is highest in children who may present with cutaneous or visceral manifestations.
Pace, David +6 more
openaire +4 more sources
Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum. [PDF]
, 2012 In most organisms, the primary function of homologous recombination (HR) is to allow genome protection by the faithful repair of DNA double-strand breaks.
Buisson, Rémi +9 more
core +2 more sources
Scientific Reports, 2020 Leishmaniases are neglected tropical diseases and Leishmania (Leishmania) infantum and Leishmania (Viannia) braziliensis are the most important causative agents of leishmaniases in the New World.
Joanna Alexandre +9 more
semanticscholar +1 more source
Canine Leishmaniosis in Greece: An Updated Countrywide Serological Study and Associated Risk Factors
Pathogens, 2021 Canine leishmaniosis (Leishmania infantum) is a zoonotic disease that affects dogs worldwide. Greece is enzootic for this disease, and updated data for its current distribution are of major importance.
Isaia Symeonidou +4 more
doaj +1 more source
Association between canine leishmaniosis and Ehrlichia canis co-infection: a prospective case-control study [PDF]
, 2018 Background In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP).
A Mazeris +55 more
core +5 more sources
Leishmania infantum Seroprevalence in Cats From Touristic Areas of Italy and Greece
Frontiers in Veterinary Science, 2020 Leishmaniosis by Leishmania infantum is a major zoonotic Vector-Borne Disease (VBD) in terms of geographic distribution, pathogenicity and zoonotic potential. While dogs are the main reservoir of L.
S. Morelli +9 more
semanticscholar +1 more source
Vaccination with Leishmania mexicana LPG induces PD-1 in CD8+ and PD-L2 in macrophages thereby suppressing the immune response: A model to assess vaccine efficacy [PDF]
Vaccine Volume 32, Issue 11, 5 March 2014, Pages 1259-1265, 2019 Leishmania lipophosphoglycan is a molecule that has been used as a vaccine candidate, with contradictory results. Since unsuccessful protection could be related to suppressed T cell responses, we analyzed the expression of inhibitory receptor PD-1 in CD8+ and CD4+ lymphocytes and it is ligand PD-L2 in macrophages of BALB/c mice immunized with various ...
arxiv +1 more source