Results 61 to 70 of about 59,567 (270)

Current status of antihistamines repurposing for infectious diseases [PDF]

arXiv, 2022
Objectives. This review gathers information on the potential role of antihistamines as anti-infective agents and identifies gaps in research that have impaired its applicability in human health. Methods. The literature search encompassed MEDLINE, PubMed and Google Scholar from 1990 to 2022. Results.
arxiv  

Study of in vitro biological activity of thiazoles on Leishmania (Leishmania) infantum

Journal of Global Antimicrobial Resistance, 2020
In the prospection of possible agents against neglected diseases, thiazole compounds are presented as promising candidates and are known to have activity against trypanosomatid parasites. Thus, this work aimed to evaluate the effects of thiazole compounds on Leishmania infantum, the aetiological agent of visceral leishmaniasis.Thiazole compounds (five ...
Marcos Veríssimo de Oliveira Cardoso, Regina Celia Bressan Queiroz de Figueiredo, Valdemiro Amaro da Silva Junior, Mary Angela Aranda de Souza, Ana Cristina Lima Leite, Rafaela Ramos Mororó Cavalcanti, Vinícius Vasconcelos Gomes de Oliveira, Vinícius Vasconcelos Gomes de Oliveira   +7 more
openaire   +4 more sources

Molecular and serological detection of Leishmania spp. in horses from an endemic area for canine visceral leishmaniasis in southeastern Brazil

Pesquisa Veterinária Brasileira
: This study aimed to verify the occurrence of Leishmania spp. and Leishmania (Leishmania) infantum in horses from a visceral leishmaniasis endemic area in Brazil.
Julia C. Benassi, Graziella U. Benvenga, Helena L. Ferreira, Rodrigo M. Soares, Diogo T. Silva, Vanessa F. Pereira, Vera Letticie A. Ruiz, Trícia Maria F. de S. Oliveira   +7 more
doaj   +1 more source

The use of kDNA minicircle subclass relative abundance to differentiate between Leishmania (L.) infantum and Leishmania (L.) amazonensis

Parasites & Vectors, 2017
Background Leishmaniasis is a neglected disease caused by many Leishmania species, belonging to subgenera Leishmania (Leishmania) and Leishmania (Viannia).
Marcello Ceccarelli, Luca Galluzzi, Aurora Diotallevi, Francesca Andreoni, Hailie Fowler, Christine Petersen, Fabrizio Vitale, Mauro Magnani   +7 more
doaj   +1 more source

Demographics and travel history of imported and autochthonous cases of leishmaniosis in dogs in the United States and Canada, 2006 to 2019

Journal of Veterinary Internal Medicine, 2021
Background Leishmania infantum infections are reported in foxhounds throughout the United States (US) and Canada, but only rarely in other dog breeds. A seroprevalence report from 2006 documented leishmaniosis in foxhounds (8.9%) tested in the US between
Taylor Estes Gin, Erin Lashnits, James M. Wilson, Edward B. Breitschwerdt, Barbara Qurollo   +4 more
doaj   +1 more source

First Detection and Molecular Analysis of Leishmania infantum DNA in Sand Flies of Kosovo

Pathogens, 2023
Phlebotomine sand flies (Diptera: Psychodidae) are the principal vectors of phleboviruses and Leishmania spp., the causative agents of leishmaniases. The Mediterranean sand fly fauna is diverse, and leishmaniasis, mainly caused by Leishmania infantum, is
Betim Xhekaj, Ina Hoxha, Katharina Platzgummer, Edwin Kniha, Julia Walochnik, Kurtesh Sherifi, Agim Rexhepi, Behlul Behluli, Vit Dvořák, Hans-Peter Fuehrer, Adelheid G. Obwaller, Wolfgang Poeppl, Jovana Stefanovska, Aleksandar Cvetkovikj   +13 more
doaj   +1 more source

Ethanolic extract of Croton blanchetianus Ball induces mitochondrial defects in Leishmania amazonensis promastigotes [PDF]

Anais da Academia Brasileira de Ciências, 2020
Leishmaniasis is a neglected disease caused by Leishmania. Chemotherapy remains the mainstay for leishmaniasis control; however, available drugs fail to provide a parasitological cure, and are associated with high toxicity. Natural products are promising
KATILY L.G. PEREIRA, NANCY B.R. VASCONCELOS, JULIANA V.C. BRAZ, JOB D.F. INÁCIO, CHARLES S. ESTEVAM, CRISTIANE B. CORREA, ROBERTA P.M. FERNANDES, ELMO E. ALMEIDA-AMARAL, RICARDO SCHER   +8 more
doaj   +1 more source

The Gut Microbiome of the Vector Lutzomyia longipalpis Is Essential for Survival of Leishmania infantum

mBio, 2017
The vector-borne disease leishmaniasis, caused by Leishmania species protozoa, is transmitted to humans by phlebotomine sand flies. Development of Leishmania to infective metacyclic promastigotes in the insect gut, a process termed metacyclogenesis, is ...
Patrick H. Kelly, S. Bahr, T. D. Serafim, N. Ajami, J. Petrosino, C. Meneses, J. Kirby, J. Valenzuela, S. Kamhawi, M. Wilson   +9 more
semanticscholar   +1 more source

Mucocutaneous Leishmaniasis due to Leishmania infantum Infection

Acta Dermato-Venereologica, 2022
Abstract is missing (Short communcation)
Kai-Philipp Linse, Christian Bogdan, Holger A. Haenssle, Ferdinand Toberer   +3 more
openaire   +3 more sources

Profiling Serine Hydrolases in the Leishmania Host‐Pathogen Interactome Using Cell‐Permeable Activity‐Based Fluorophosphonate Probes

ChemBioChem, Accepted Article.
Leishmaniasis, a vector borne neglected tropical disease, caused by the protozoan parasite Leishmania, is a major global public health challenge with millions of new cases annually. Treatment of leishmaniasis is difficult for many reasons including a multiple life‐cycle stages, involving both an infective insect vector form, the promastigote, and a ...
Jaime A. Isern, Exequiel O.J. Porta, Karunakaran Kalesh, Zisis Koutsogiannis, Davide Cazzola, Ehmke Pohl, Paul Denny, Patrick G. Steel   +7 more
wiley   +1 more source