A Calcium- and GTP-Dependent Transglutaminase in Leishmania infantum
Veterinary Sciences, 2023 While human and animal leishmaniasis affect several millions of people worldwide, L. infantum is the species responsible for visceral leishmaniasis in Europe, Middle East, and America. Antileishmanial drugs present issues associated with drug toxicity and increasing parasite resistance.
Almugadam, Shawgi Hago +7 more
openaire +4 more sources
Parasites & Vectors, 2012 Background Sand flies are the only biologically adapted vectors of Leishmania parasites, however, a possible role in the transmission of Leishmania has been proposed for other hematophagous ectoparasites such as ticks.
Solano-Gallego Laia +6 more
doaj +1 more source
The recombinant protein rSP03B is a valid antigen for screening dog exposure to Phlebotomus perniciosus across foci of canine leishmaniasis [PDF]
, 2017 The frequency of sandfly-host contacts can be measured by host antibody levels against sandfly salivary proteins. Recombinant salivary proteins are suggested to represent a valid replacement for salivary gland homogenate (SGH); however, it is necessary ...
Alten +23 more
core +2 more sources
Boundary behaviours of Leishmania mexicana: a hydrodynamic simulation study [PDF]
, 2018 It is well established that the parasites of the genus Leishmania exhibit complex surface interactions with the sandfly vector midgut epithelium, but no prior study has considered the details of their hydrodynamics. Here, the boundary behaviours of motile Leishmania mexicana promastigotes are explored in a computational study using the boundary element
arxiv +1 more source
Proteome Profiling of Leishmania Infantum Promastigotes
Journal of Eukaryotic Microbiology, 2011 ABSTRACT. A proteome analysis of the promastigote stage of the trypanosomatid parasite Leishmania infantum (MON‐1 zymodeme) is described here for the first time. Total protein extracts were prepared at early logarithmic and stationary phases of replicate axenic cultures and processed by 2D electrophoresis (pH 3–10).
Alcolea, Pedro J. +2 more
openaire +4 more sources
Paf-Metabolic Enzymes and Paf-like Activity in and Promastigotes
European Journal of Inflammation, 2011 Leishmania spp are obligate intracellular protozoan parasites of the mononuclear phagocyte system that cause a spectrum of diseases known as leishmaniasis.
P. Chatzovoulos +5 more
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2010 INTRODUÇÃO: Leishmaniose visceral é uma zoonose que acomete diversos mamíferos tendo os canídeos domésticos como principais reservatórios em ambiente urbano.
Nely Pinheiro Souza +6 more
doaj +1 more source
Early suppression of lymphoproliferative response in dogs with natural infection by Leishmania infantum. [PDF]
, 1999 Dogs are the domestic reservoirs of zoonotic visceral leishmaniasis caused by Leishmania infantum. Early detection of canine infections evolving to clinically patent disease may be important to leishmaniasis control.
CIARAMELLA, PAOLO +8 more
core +1 more source
Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]
, 2020 The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA +13 more
core +1 more source
Compressed AFM-IR hyperspectral nanoimaging of single Leishmania parasites [PDF]
arXiv, 2022 Infrared hyperspectral imaging is a powerful approach in the field of materials and life sciences. However, the extension to modern sub-diffraction nanoimaging still remains a highly inefficient technique, as it acquires data via inherent sequential schemes.
arxiv