Parasites & Vectors, 2019 Background Neutrophils play an immunomodulatory role through the release of neutrophil extracellular traps (NETs). NETs are released in response to Leishmania infection, but the mechanism of NET extrusion has not been elucidated.
Furong Wei +6 more
doaj +1 more source
Scientific Reports, 2020 Leishmaniases are neglected tropical diseases and Leishmania (Leishmania) infantum and Leishmania (Viannia) braziliensis are the most important causative agents of leishmaniases in the New World.
Joanna Alexandre +9 more
semanticscholar +1 more source
Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]
, 2020 The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA +13 more
core +1 more source
Early suppression of lymphoproliferative response in dogs with natural infection by Leishmania infantum. [PDF]
, 1999 Dogs are the domestic reservoirs of zoonotic visceral leishmaniasis caused by Leishmania infantum. Early detection of canine infections evolving to clinically patent disease may be important to leishmaniasis control.
CIARAMELLA, PAOLO +8 more
core +1 more source
Leishmania infantum Seroprevalence in Cats From Touristic Areas of Italy and Greece
Frontiers in Veterinary Science, 2020 Leishmaniosis by Leishmania infantum is a major zoonotic Vector-Borne Disease (VBD) in terms of geographic distribution, pathogenicity and zoonotic potential. While dogs are the main reservoir of L.
S. Morelli +9 more
semanticscholar +1 more source
Antiparasitic effect of synthetic aromathecins on Leishmania infantum [PDF]
BMC Veterinary Research, 2019 Abstract Background Canine leishmaniasis is a zoonotic disease caused by Leishmania infantum, being the dogs one of the major reservoirs of human visceral leishmaniasis. DNA topology is a consolidated target for drug discovery. In this regard, topoisomerase IB – one of the enzymes controlling DNA topology – has been poisoned by hundreds of compounds ...
Rosa M. Reguera +6 more
openaire +5 more sources
The recombinant cysteine proteinase B (CPB) from Leishmania braziliensis and its domains: promising antigens for serodiagnosis of cutaneous and visceral leishmaniasis in dogs. [PDF]
, 2019 Leishmaniasis represents a group of parasitic diseases caused by a protozoan of the genus Leishmania and is widely distributed in tropical and subtropical regions.
Basombrío, Manuel Alberto +10 more
core +1 more source
Cryptic
BMC Infectious Diseases, 2009 Background Visceral leishmaniasis (VL) is a protozoan diseases caused in Europe by Leishmania (L.) infantum. Asymptomatic Leishmania infection is more frequent than clinically apparent disease.
Rubino Raffaella +10 more
doaj +1 more source
Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines
Parasites & Vectors, 2020 Background One of the major challenges to leishmaniasis treatment is the emergence of parasites resistant to antimony. To study differentially expressed genes associated with drug resistance, we performed a comparative transcriptomic analysis between ...
Juvana M Andrade +13 more
semanticscholar +1 more source
Leishmania (infantum) chagasi in canine urinary sediment [PDF]
Revista Brasileira de Parasitologia Veterinária, 2015 Canine visceral leishmaniasis (CVL) is difficult to diagnosis, mainly due to the presence of asymptomatic animals, the diversity of clinical symptoms and the difficulty in obtaining diagnostic evidence of high sensitivity and specificity. The purpose of this study was to diagnose CVL in urinary sediment of 70 dogs of different breeds, sexes and ages ...
Mendonça, Ivete Lopes de +2 more
openaire +5 more sources