Results 71 to 80 of about 14,623 (258)

2-Substituted quinoline alkaloids as potential antileishmanial drugs [PDF]

, 1993
Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp.
Barrios, A.A., Bruneton, J., Cavé, A., Fournet, Alain, Hocquemiller, R., Munoz, V.   +5 more
core   +1 more source

Phototoxic effect of aluminium-chlorine and aluminium-hydroxide phthalocyanines on Leishmania (l.) amazonensis

Photodiagnosis and Photodynamic Therapy, 2018
This study investigated the activity of photosensitive phthalocyanines on promastigotes and amastigotes of Leishmania (L.) amazonensis. Aluminum phthalocyanine chloride (AlPcCl), Aluminum phthalocyanine hydroxide (AlPcOH) and zinc phthalocyanine (PcZn) were tested in the presence (matte red LED, potency of 2.5-2.3 μW for 30 min) and absence of light ...
V, Nesi-Reis, T R, Navasconi, D S S L, Lera-Nosone, E L, Oliveira, P M, Barbosa, W, Caetano, T G V, Silveira, S M A, Aristides, N, Hioka, M V C, Lonardoni   +9 more
openaire   +2 more sources

In vitro study of homeopathic medicines in macrophages co-cultured with Leishmania (L.) amazonensis

International Journal of High Dilution Research - ISSN 1982-6206, 2021
Background: In previous studies the effect of homeopathic medicines in murine cutaneous Leishmaniasis were described, indicating immunomodulation. The phagocytes migration and their activity increased after Thymulin 5cH and decreased after Antimonium crudum 30cH treatment.
Leoni Villano Bonamin, Fabiana Rodrigues De Santana, Fabiana Toshie De Camargo Konno, Luciane Costa Dalboni, Amarylis T. Cesar, Cideli de Paula Coelho, Dorly Buchi, Márcia Dalastra Laurenti, Elizabeth Cristina Perez Hurtado   +8 more
openaire   +1 more source

Tegumentary Leishmaniasis Associated With Immune Reconstitution in an HIV Patient—A Case Report

Parasite Immunology, Volume 48, Issue 5, May 2026.
ABSTRACT HIV‐associated Immune Reconstitution Inflammatory Syndrome (IRIS) may significantly alter the immunopathological presentation of American Tegumentary Leishmaniasis (ATL), occasionally causing paradoxical clinical exacerbations. We report the long‐term follow‐up of a 39‐year‐old female coinfected with HIV and disseminated mucocutaneous ...
Marilia Brasil Xavier, Claudia Maria de Castro Gomes, Rita Catarina Medeiros Sousa, Edna Aoba Yassui Ishikawa, Elza Baía de Brito, Silvia Ferreira Rodrigues Müller, Lucas dos Santos Fontes, João Augusto Gomes de Souza Monteiro de Brito, Larissa dos Santos Alcantara, Carlos Eduardo Pereira Corbett   +9 more
wiley   +1 more source

Exploring the Role of the MAPK Signalling Pathway in Dog Immunity: From Cancer to Parasitic Diseases

Parasite Immunology, Volume 48, Issue 5, May 2026.
ABSTRACT Mitogen‐activated protein kinases (MAPKs) are intracellular signalling proteins that modulate several cellular processes, such as proliferation, cytokine production and survival. Like humans, dogs may exhibit changes in MAPK signalling under pathological conditions.
Francini Neves Ribeiro, Fernanda Nazaré Morgado, Renato Porrozzi   +2 more
wiley   +1 more source

Leishmania infantum and Leishmania braziliensis : differences and similarities to evade the innate immune system [PDF]

, 2016
Visceral leishmaniasis is a severe form of the disease, caused by Leishmania infantum in the New World. Patients present an anergic immune response that favors parasite establishment and spreading through tissues like bone marrow and liver.
Bernardes, Daniela M., Falcão, Sarah de Athayde Couto, Favali, Cecilia Beatriz Fiuza, Ferreira, Luciana G., Jaramillo, Tatiana María Giraldo, Santana, Jaime Martins de   +5 more
core   +2 more sources

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm, Muhammad Jawad Nasim, Claus Jacob   +2 more
wiley   +1 more source

Sequence analysis of the 3-untranslated region of HSP70 (type I) genes in the genus Leishmania: Its usefulness as a molecular marker for species identification [PDF]

, 2015
Background: The Leishmaniases are a group of clinically diverse diseases caused by parasites of the genus Leishmania. To distinguish between species is crucial for correct diagnosis and prognosis as well as for treatment decisions.
Cañavate, Carmen, Chicharro, Carmen, García, Lineth, Parrado, Rudy, Puerta, Concepción J., Requena, José María   +5 more
core   +1 more source

Comparative two-dimensional gel electrophoresis maps for promastigotes of Leishmania amazonensis and Leishmania major

Brazilian Journal of Infectious Diseases
The outcome of Leishmania infections is determined by both the parasite species and the host genetic makeup. While much has been learned regarding immune responses to this parasite, our knowledge on parasite-derived factors is limited.
Reynolds K. B. Brobey, Fang C. Mei, Xiaodong Cheng, Lynn Soong   +3 more
doaj   +1 more source

Neutrophils reduce the parasite burden in Leishmania (Leishmania) amazonensis-infected macrophages.

PLoS ONE, 2010
BackgroundStudies on the role of neutrophils in Leishmania infection were mainly performed with L. (L) major, whereas less information is available for L. (L) amazonensis.
Erico Vinícius de Souza Carmo, Simone Katz, Clara Lúcia Barbiéri   +2 more
doaj   +1 more source