Results 171 to 180 of about 10,324 (216)

New series of pentamidine-based 1,2,3-triazole-diaryl-hydrazones: design, synthesis, and evaluation of their leishmanicidal activity and mechanism of action against <i>Leishmania (L.) amazonensis</i>. [PDF]

RSC Med Chem
Espuri Sepini PF, Gontijo VS, Tavares LM, Souza LM, Souza THF, Couto DS, Nunes JB, Ribeiro CA, da Silva Cravo SMM, Zavan B, Alves MA, Souza HMR, Ionta M, Sousa ME, Peloso EF, Marques MJ, Viegas C.   +16 more
europepmc   +1 more source

Revisiting Leishmania (Viannia) lainsoni Silveira, Shaw, Braga, and Ishikawa, 1987: current knowledge and emerging perspectives. [PDF]

Parasit Vectors
de Morais TG, Campos MB, Silveira FT, Vasconcelos Dos Santos T.   +3 more
europepmc   +1 more source

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In vitro activity of cinnamaldehyde on Leishmania (Leishmania) amazonensis

Experimental Parasitology, 2022
Tegumentary leishmaniasis is an endemic disease that urgently needs new and effective treatments. L. amazonensis is one of the main species involved in the transmission of this infectious and non-contagious disease. The currently available treatments for leishmaniasis have high toxicity and vary in efficacy.
Aline Ávila Brustolin, Áquila Carolina Fernandes Herculano Ramos-Milaré, Tatiane França Perles de Mello, Sandra Mara Alessi Aristides, Maria Valdrinez Campana Lonardoni, Thaís Gomes Verzignassi Silveira   +5 more
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The Comparative Genomics and Phylogenomics of Leishmania Amazonensis Parasite [PDF]

Evolutionary Bioinformatics, 2014
Leishmaniasis is an infectious disease caused by Leishmania species. Leishmania amazonensis is a New World Leishmania species belonging to the Mexicana complex, which is able to cause all types of leishmaniasis infections. The L.
Diogo A Tschoeke, Gisele L Nunes, Rodrigo Jardim   +2 more
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Antileishmanial activity of cordiaquinone E towards Leishmania (Leishmania) amazonensis

International Immunopharmacology, 2021
Leishmaniasis is caused by several protozoan species of Leishmania, and being endemically present in 98 countries around the world, it is also a severe public-health problem. The available antileishmanial drugs are toxic and yet present risks of recurrent infection. Efforts to find new, effective, and safe oral agents for the treatment of leishmaniasis
Raiza Raianne Luz, Rodrigues, Thaís Amanda Lima, Nunes, Alyne Rodrigues, de Araújo, José Delano Barreto, Marinho Filho, Marcos Vinícius, da Silva, Fernando Aécio de Amorim, Carvalho, Otília Deusdenia Loiola, Pessoa, Hozana Patrícia Silva, Freitas, Klinger Antonio da Franca, Rodrigues, Ana Jérsia, Araújo   +9 more
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Detection of Leishmania (Leishmania) amazonensis and Leishmania (Leishmania) infantum chagasi in Brazilian bats

Veterinary Parasitology, 2010
Although bats are one of the most abundant mammals in the new world and are present in virtually all ecosystems, including urban and peri-urban environments, few studies have investigated the role of these animals in the epidemiological chain of leishmaniosis.
Elisa San Martin Mouriz, Savani, Marilene Fernandes, de Almeida, Maria Cecília Gibrail, de Oliveira Camargo, Sandra Regina Nicoletti, D'Auria, Miriam Martos Sodré, Silva, Maria Lúcia, de Oliveira, Débora, Sacramento   +6 more
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Characterization of Leishmania (Leishmania) amazonensis promastigotes resistant to pentamidine

Experimental Parasitology, 2008
Pentamidine is a second-line agent used in the treatment of leishmaniasis and its mode of action and mechanism of resistance is not well understood. It was previously demonstrated that transfection of promastigotes and amastigotes with the ABC transporter PRP1 gene confers resistance to pentamidine.
Adriano C, Coelho, Luciana G, Gentil, José Franco, da Silveira, Paulo C, Cotrim   +3 more
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Biochemical characterization of serine transport in Leishmania (Leishmania) amazonensis

Molecular and Biochemical Parasitology, 2009
In addition to its role as a protein component in Leishmania, serine is also a precursor for the synthesis of both phosphatidylserine, which is a membrane molecule involved in parasite invasion and inactivation of macrophages, and sphingolipids, which are necessary for Leishmania to differentiate into its infective forms.
Marcos Gonzaga, dos Santos, Lisvane Silva, Paes, Ricardo Andrade, Zampieri, Maria Fernanda Laranjeira, da Silva, Ariel Mariano, Silber, Lucile Maria, Floeter-Winter   +5 more
openaire   +2 more sources