Results 211 to 220 of about 66,437 (256)
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Veterinary Parasitology: Regional Studies and Reports, 2020
In the present study, we reported the natural infection by Leishmania sp. in a domestic cat, in which the amastigote forms of the parasite were observed within a lesion on its ear-tip.
L. A. Carneiro +5 more
semanticscholar +1 more source
In the present study, we reported the natural infection by Leishmania sp. in a domestic cat, in which the amastigote forms of the parasite were observed within a lesion on its ear-tip.
L. A. Carneiro +5 more
semanticscholar +1 more source
Characterization of Leishmania (Leishmania) amazonensis promastigotes resistant to pentamidine
Experimental Parasitology, 2008Pentamidine is a second-line agent used in the treatment of leishmaniasis and its mode of action and mechanism of resistance is not well understood. It was previously demonstrated that transfection of promastigotes and amastigotes with the ABC transporter PRP1 gene confers resistance to pentamidine.
Adriano C, Coelho +3 more
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Biochemical characterization of serine transport in Leishmania (Leishmania) amazonensis
Molecular and Biochemical Parasitology, 2009In addition to its role as a protein component in Leishmania, serine is also a precursor for the synthesis of both phosphatidylserine, which is a membrane molecule involved in parasite invasion and inactivation of macrophages, and sphingolipids, which are necessary for Leishmania to differentiate into its infective forms.
Marcos Gonzaga, dos Santos +5 more
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Polyamine N-acetyltransferase in Leishmania amazonensis
Parasitology Research, 1996N-Acetyltransferase, which is suggested to be responsible for the production of N1-acetylspermidine in Leishmania amazonensis and to be involved in the process of inactivation and degradation of excessive polyamines, was partially purified and characterized. Among the substrates tested, sym-norspermidine, sym-norspermine, and 1,3-diaminopropane had the
M, Rojas-Chaves +2 more
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Chemical Biology and Drug Design, 2019
Isoxazole analogues derived from the neolignans veraguensin, grandisin, and machilin G were previously synthesized with different substitution patterns through the bioisosterism strategy.
Amarith R. Neves +10 more
semanticscholar +1 more source
Isoxazole analogues derived from the neolignans veraguensin, grandisin, and machilin G were previously synthesized with different substitution patterns through the bioisosterism strategy.
Amarith R. Neves +10 more
semanticscholar +1 more source
Heme binding to Leishmania mexicana amazonensis
Molecular and Biochemical Parasitology, 1988Leishmania mexicana amazonensis is a pathogenic parasite whose growth, due to a biosynthetic deficiency, is dependent on a supply of exogenous heme. Utilizing [55Fe]hemin, we have demonstrated that heme binding to non-dividing cultured promastigotes of L. m.
R A, Galbraith, M J, McElrath
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Leishmania (Viannia) panamensis/Leishmania (Leishmania) amazonensis—A Warning
Parasitology Today, 1999The parasite Leishmania (Viannia) panamensis causes local cutaneous lesions. The Laboratory of Infectious Disease Pathology of the University of Sao Paulo Medical School has been working with a strain of Leishmania (Viannia) panamensis, HSJD-1, characterized by isoenzyme at the Liverpool School of Tropical Medicine, by W.
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Leishmania amazonensis: Acidic organelles in amastigotes
Experimental Parasitology, 1988Leishmania amastigotes are intracellular protozoan parasites which exclusively invade cells of the macrophage series and multiply within phagolysosomes. Recent studies showed that intracellular and isolated amastigotes of L. amazonesis are killed by amino acid esters which appear to be trapped within as yet unidentified, possibly acidified, "lysosome ...
J C, Antoine +3 more
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Cell Biology International
AbstractLeishmaniases affect millions of people around the world, caused by Leishmania parasites. Leishmania are transmitted by female sandflies from Phlebotominae subfamily during their blood meals. In mammals, promastigotes are phagocytosed mainly by macrophages, differentiate into amastigotes and multiply.
Tainá Cavalcante +7 more
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AbstractLeishmaniases affect millions of people around the world, caused by Leishmania parasites. Leishmania are transmitted by female sandflies from Phlebotominae subfamily during their blood meals. In mammals, promastigotes are phagocytosed mainly by macrophages, differentiate into amastigotes and multiply.
Tainá Cavalcante +7 more
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Leishmania amazonensis response to artemisinin and derivatives
Parasitology International, 2021The worldwide presence of Leishmania parasites increases in the poorest regions. Current leishmaniasis treatments are unsatisfactory due to resistance development, side effects and cost. Herein, we describe the in vitro activity of artemisinin (ART), artemether (ATM), artesunate (ATS) and dihydroartemisinin (DHA) against Leishmania amazonensis ...
Laura, Machín +3 more
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