Results 221 to 230 of about 66,437 (256)

Genomic organization of telomeric and subtelomeric sequences of Leishmania (Leishmania) amazonensis

International Journal for Parasitology, 2005
Telomeres are DNA-protein complexes that protect linear chromosomes from degradation and fusions. Telomeric DNA is repetitive and G-rich, and protrudes towards the end of the chromosomes as 3'G-overhangs. In Leishmania spp., sequences adjacent to telomeres comprise the Leishmania conserved telomere associated sequences (LCTAS) that are around 100 bp ...
F F, Conte, M I N, Cano
openaire   +2 more sources

Histopathological studies of visceralized Leishmania (Leishmania) amazonensis in mice experimentally infected

Veterinary Parasitology, 2004
BALB/c, C57BL/6, and DBA/2 mice were subcutaneously infected in the left footpad by injecting 10(4) Leishmania (Leishmania) amazonensis amastigotes. Mice were sacrificed 20, 30, 40, 60 and 90 days post-infection. Fragments of liver, kidney, spleen, skin, and draining lymph node were collected for histological examination.
A L, Abreu-Silva, K S, Calabrese, S M N, Cupolilo, F O, Cardoso, C S F, Souza, S C, Gonçalves da Costa   +5 more
openaire   +2 more sources

Active Transport of Glutamate in Leishmania (Leishmania) amazonensis

Journal of Eukaryotic Microbiology, 2008
ABSTRACT. Leishmania spp. are the causative agents of leishmaniasis, a complex of diseases with a broad spectrum of clinical manifestations. Leishmania (Leishmania) amazonensis is a main etiological agent of diffuse cutaneous leishmaniasis. Leishmania spp., as other trypanosomatids, possess a metabolism based significantly on the consumption of amino
Lisvane S, Paes, Robert L, Galvez Rojas, Anissa, Daliry, Lucile M, Floeter-Winter, Marcel I, Ramirez, Ariel M, Silber   +5 more
openaire   +2 more sources

Leishmania (Leishmania) amazonensis: purification and characterization of a promastigote serine protease

Experimental Parasitology, 2004
Pathogenic protozoan proteases play crucial roles in the host-parasite interaction, and its characterization contributes to the understanding of protozoan disease mechanisms. A Leishmania amazonensis promastigote protease was purified 36-fold, using aprotinin-agarose affinity chromatography and gel filtration high performance liquid chromatography ...
Raquel Elisa, da Silva-Lopez, Salvatore, Giovanni-De-Simone   +1 more
openaire   +2 more sources

Subcellular localization of an extracellular serine protease in Leishmania (Leishmania) amazonensis

Parasitology Research, 2004
Extracellular proteolytic activity was detected in a Leishmania ( L.) amazonensis culture supernatant and a 56-kDa protein was purified using (NH4)2SO4 precipitation followed by affinity chromatography on aprotinin-agarose. A rabbit serum obtained against the 56-kDa extracellular serine protease was used in order to analyze its location in L.
R E, Silva-Lopez, J A, Morgado-Díaz, C R, Alves, S, Côrte-Real, S, Giovanni-De-Simone   +4 more
openaire   +2 more sources

Immunomodulatory activity of ouabain in Leishmania leishmania amazonensis-infected Swiss mice

Parasitology Research, 2012
Ouabain is a cardiotonic steroid identified as an endogenous substance of human plasma, being produced by the adrenal, pituitary, and hypothalamus. Despite the studies demonstrating the ability of ouabain to modulate inflammation and other aspects of the immune response, the effects of this substance in Leishmaniasis is unknown.
P L, Jacob, J A, Leite, A K A, Alves, Y K S, Rodrigues, F M, Amorim, P L N, Néris, M R, Oliveira, S, Rodrigues-Mascarenhas   +7 more
openaire   +2 more sources

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly  

Antileishmanial activity of verbascoside: Selective arginase inhibition of intracellular amastigotes of Leishmania (Leishmania) amazonensis with resistance induced by LPS plus IFN‐&ggr;

Biochemical Pharmacology, 2017
Claudia do Carmo Maquiaveli, A. L. Rochetti, H. Fukumasu, P. Vieira, E. R. da Silva   +4 more
semanticscholar   +1 more source

The first records of Leishmania (Leishmania) amazonensis in dogs (Canis familiaris) diagnosed clinically as having canine visceral leishmaniasis from Araçatuba County, São Paulo State, Brazil.

Veterinary parasitology, 2007
J. E. Tolezano, S. Uliana, H. H. Taniguchi, M. F. Araújo, J. A. R. Barbosa, J. A. R. Barbosa, L. Floeter-Winter, J. Shaw   +7 more
semanticscholar   +1 more source

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

Ca-A Cancer Journal for Clinicians, 2017
Cynthia Morata-Tarifa, Joyce M Slingerland   +1 more
exaly