Results 61 to 70 of about 6,523 (205)

A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis [PDF]

Previous studies demonstrated safety, immunogenicity and efficacy of DNA/modified vaccinia virus Ankara (MVA) prime/boost vaccines expressing tryparedoxin peroxidase (TRYP) and Leishmania homologue of the mammalian receptor for activated C kinase (LACK ...
Alcami, Antonio, Antoniou, Maria, Begoña Ruiz-Argüello, Maria, Blackwell, Jenefer M., Carson, Connor, Christodoulou, Vasiliki, Courtenay, Orin, Messaritakis, Ippokratis   +7 more
core   +1 more source

Dog skin parasite load, TLR-2, IL-10 and TNF-α expression and infectiousness [PDF]

, 2017
Visceral leishmaniosis is a zoonotic disease that is transmitted by Lutzomyia longipalpis sandflies. Dogs are the main peri-urban reservoir of the disease, and progression of canine leishmaniosis is dependent on the type of immune response elaborated ...
Avanço, S. V., Beloti, C. A. C., Calvo-Bado, Leo A., Cipriano, R. S., Courtenay, Orin, Hiramoto, R. M., Ito, P. K. R. K., Lima, V. M. F., Machado, G. F., Nunes, C. M., Oliveira-Rovai, F. M., Pereira-Fonseca, D. C. M., Rodas, L. A. C., Torrecilha, R. B. P., Utsunomiya, Y. T.   +14 more
core   +1 more source

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

Veterinary Dermatology, EarlyView.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik, A. Di Loria, L. Archer, M. Saridomichelakis, A. S. Benvenuto, D. Santoro   +5 more
wiley   +1 more source

Study of Leishmania pathogenesis in mice : experimental considerations [PDF]

, 2015
Although leishmaniases are endemic in 98 countries, they are still considered neglected tropical diseases. Leishmaniases are characterized by the emergence of new virulent and asymptomatic strains of Leishmania spp.
A Asadpour, a L Bañuls, A Sakthianandeswaren, A Sulahian, AC Rosypal, AH Fortier, AL Bañuls, Anne-Laure Bañuls, B a Mock, C Kébaïer, CM Theodos, Corinne Loeuillet, CR Engwerda, D Sacks, DJ Bradley, E Mougneau, EV Davies, F Oliveira, GF Mitchell, GS Nabors, HC Lima, HW Murray, J Li, JE Uzonna, JE Uzonna, JG Howard, JM Blackwell, JM Blackwell, JN Menon, JP Dedet, JP Gangneux, KE Squires, LJ DeTolla, M Hide, M Paranhos, M Roberts, Mallorie Hide, MH Alimohammadian, ML Mbow, N Rolão, N Singh, NB Norsworthy, OR Rodrigues, P Desjeux, P Mukherjee, PA Bretscher, PC Melby, PM Kaye, R Lira, RG Titus, RV Morris, S Gomes-Pereira, S Honoré, S Kaur, S Lopez Kostka, SC Smelt, SD Cangussú, SJ Foote, T Baptista-Fernandes, T Lang, TM Doherty, V Leclercq, W Markikou-Ouni, Y Belkaid, Y Belkaid, Y Belkaid   +65 more
core   +4 more sources

Factors Associated With the Emergence and Spread of Visceral Leishmaniasis in the State of São Paulo, Brazil

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Visceral leishmaniasis (VL), once considered a rural disease in Brazil, has progressively urbanised, particularly in the state of São Paulo (SSP), where the first urban cases emerged after the detection of the vector Lutzomyia longipalpis in 1997.
Vera Lucia Fonseca de Camargo‐Neves, Guilherme Loureiro Werneck   +1 more
wiley   +1 more source

Complete conservation of an immunogenic gene (lcr1) in Leishmania infantum and Leishmania chagasi isolated from Iran, Spain and Brazi [PDF]

Journal of Vector Borne Diseases, 2010
Background & objectives: Kala-azar is the visceral and most severe form of leishmaniasis thatleads to death if untreated. The causative agents of visceral leishmaniasis (VL) are members ofLeishmania (L.) donovani complex which includes L.
H. Mahmoudzadeh-Niknam , F. Abrishami , M. Doroudian , M. Moradi , M.H. Alimohammadian , P. Parvizi
doaj  

Comparative Genomic Analyses of New and Old World Viscerotropic Leishmanine Parasites: Further Insights into the Origins of Visceral Leishmaniasis Agents

Microorganisms, 2022
Visceral leishmaniasis (VL), also known as kala-azar, is an anthropozoonotic disease affecting human populations on five continents. Aetiologic agents belong to the Leishmania (L.) donovani complex.
Fernando Tobias Silveira, Edivaldo Costa Sousa Junior, Rodrigo Vellasco Duarte Silvestre, Thiago Vasconcelos dos Santos, Wilfredo Sosa-Ochoa, Concepción Zúniga Valeriano, Patrícia Karla Santos Ramos, Samir Mansour Moraes Casseb, Luciana Vieira do Rêgo Lima, Marliane Batista Campos, Vania Lucia da Matta, Claudia Maria Gomes, Gabriela V. Araujo Flores, Carmen M. Sandoval Pacheco, Carlos Eduardo Corbett, Márcia Dalastra Laurenti   +15 more
doaj   +1 more source

Drug susceptibility of Leishmania infantum (syn. Leishmania chagasi) isolates from Brazilian HIV-positive and HIV-negative patients [PDF]

Journal of Antimicrobial Chemotherapy, 2011
Laboratory for Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium; Nucleo de Medicina Tropical, Universidade de Brasilia, DF, Brazil; Departamento de Patologia do Centro de Ciencias Biologicas e da Saude da Universidade ...
Inocêncio da Luz, R., Romero, G. A., Dorval, M. E., Cruz, I., Canavate, C., Dujardin, J. C., Van Assche, T., Cos, P., Maes, L.   +8 more
openaire   +5 more sources

Infectiousness in a Cohort of Brazilian Dogs: Why Culling Fails to Control Visceral Leishmaniasis in Areas of High Transmission [PDF]

, 2002
The elimination of seropositive dogs in Brazil has been used to control zoonotic visceral leishmaniasis but with little success. To elucidate the reasons for this, the infectiousness of 50 sentinel dogs exposed to natural Leishmania chagasi infection was
Courtenay, O., Dye, C., Garcez, L.M., Quinnell, R.J., Shaw, J.J.   +4 more
core  

Association between canine leishmaniosis and Ehrlichia canis co-infection: a prospective case-control study [PDF]

, 2018
Background In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP).
A Mazeris, A Saha, A Sainz, AS De Tommasi, C Attipa, C Attipa, C Maia, CB Cardinot, CF Alves, Charalampos Attipa, Chris Helps, CL Barbieri, CLA Ehrlichiosis, D Chochlakis, D Otranto, D Otranto, David Morris, Francesca Soutter, G Baneth, G Baneth, J Alvar, J Franca-Costa, J Le Gal, J Moreno, K Katherine, Kostas Papasouliotis, L Cortese, L Cortese, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, M Novacco, M Olivier, M-D Tabar, MG Vrhovec, MJ Day, MJ Grigg, P Parola, P Seneviratna, R Killick-Kendrick, RB Kline, RJ Quinnell, RN Davidson, S Carver, S Davies, S Harrus, S Harrus, S Tasker, Scott Carver, SE Shaw, Séverine Tasker, T Bouzouraa, V Pintado, WH Pryor Jr, Y Mekuzas, Y Rosseel   +55 more
core   +5 more sources