Characterization of the Effect of N-(2-Methoxyphenyl)-1-methyl-1H-benzimidazol-2-amine, Compound 8, against Leishmania mexicana and Its In Vivo Leishmanicidal Activity. [PDF]
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Isolation of Leishmania mexicana mexicana from Lutzomyia ylephiletor in Guatemala
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Stage-specific proteinases ofLeishmania mexicana mexicanapromastigotes
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Phosphomonoesterases of Leishmania mexicana mexicana and other flagellates
Molecular and Biochemical Parasitology, 1987Amastigotes and log-phase promastigotes of Leishmania mexicana mexicana contained distinct acid phosphatase, 3'-nucleotidase and 5'-nucleotidase activities, distinguishable by their response to pH and inhibitors. Both tartrate-sensitive and tartrate-resistant acid phosphatase were present in the two forms, amastigotes possessed less tartrate-resistant ...
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Mastomys natalensis as an experimental host for Leishmania mexicana mexicana
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1978Young multimammate rats (Mastomys natalensis) can be readily infected when inoculated intradermally with the amastigotes of Leishmania mexicana mexicana. Lesions appear at the site of inoculation in the second week of infection and continue to increase in size for the first month; amastigotes can be detected during this period.
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Sterols of ketoconazole-inhibited Leishmania mexicana mexicana promastigotes
Molecular and Biochemical Parasitology, 1985Leishmania mexicana mexicana promastigotes grown with cholesterol, supplied in natural products as the free sterol and as cholesteryl esters, were exposed to [2-14C]mevalonate and to the antimycotic drug ketoconazole. Growth was inhibited and cholesterol and 14 alpha-methyl sterols accumulated in free and esterified forms (cholesterol much greater than
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Glucose transport in amastigotes and promastigotes of Leishmania mexicana mexicana
Molecular and Biochemical Parasitology, 1995Promastigotes and amastigotes of Leishmania mexicana mexicana transported 2-deoxy-D-glucose (2-DOG) by a saturable process with a Km of 24 +/- 3 microM and Vmax of 2.21 nmol min-1 (mg protein)-1 for the promastigote and a Km of 29 +/- 8 microM and Vmax of 0.13 nmol min-1 (mg protein)-1 for the amastigote stage.
R J, Burchmore, D T, Hart
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Leishmania tropica and Leishmania mexicana: Cross-immunity in mice
Experimental Parasitology, 1978Abstract The effect of a previous or concurrent Leishmania tropica major infection on a L. mexicana infection was studied. Mice which were recovering from or had recovered from a L. tropica infection were found to be totally resistant to L. mexicana. Infection of mice already carrying a L. mexicana infection with L.
J, Alexander, R S, Phillips
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The Leishmania mexicana proteasome
Molecular and Biochemical Parasitology, 1999As a start to understanding the importance of intracellular proteolysis in the protozoon Leishmania mexicana, the parasite proteasome has been purified and characterised. The L. mexicana proteasome is similar to proteasomes from other eukaryotes. It is soluble, and the 20S form has a mass of around 670 kDa, composed of at least 10 distinct subunits in ...
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