Results 191 to 200 of about 14,552 (222)
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Leishmania mexicana: Energy metabolism of amastigotes and promastigotes
Experimental Parasitology, 1982Abstract The utilisation of substrates by Leishmania mexicana amastigotes and promastigotes differed significantly. The rates of uptake and catabolism of nonesterified fatty acids were up to 10-fold higher with amastigotes. Almost all the available exogenous fatty acids were consumed during amastigote transformation and by stationary phase of ...
D T, Hart, G H, Coombs
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ANTIPROLIFERATIVE EFFECT OF ILLIMAQUINONE ON LEISHMANIA MEXICANA
Cell Biology International, 1997Illimaquinone, a sponge metabolite that disrupts the Golgi complex in mammalian cells, stopped proliferation and induced morphological and ultrastructural changes in promastigotes of L. mexicana Radioactive labeling of proteins demonstrates an increased excretion function and diminution of membrane acid phosphatase activity, due probably to the ...
H R, Rangel, F, Dagger, R S, Compagnone
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Leishmania mexicana: Amastigote hydrolases in unusual lysosomes
Experimental Parasitology, 1986Leishmania mexicana mexicana (M379) amastigotes were found to contain much higher activities than cultured promastigotes of five putative lysosomal enzymes: cysteine proteinase; arylsulfatase (EC 3.1.6.1); beta-glucuronidase (EC 3.2.1.31); DNase (EC 3.1.22.1), and RNase (EC 3.1.27.1).
M F, Pupkis, L, Tetley, G H, Coombs
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Evidence for a Membrane Adenosine Receptor in Leishmania Mexicana Mexicana (WR 227)
1986Leishmania spp., a Protozoan Parasite transmitted to the mammalian host by the sand fly (genus Phlebotomus), produces a disease manifested in the cutaneous, mucocutaneous or visceral form. The choice of drugs has been limited primarily to the pentavalent antimonial compounds.
B D, Hansen +2 more
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Leishmania mexicana: Molecular cloning and characterization of enolase
Experimental Parasitology, 2007The gene of Leishmania mexicana enolase was cloned and overexpressed in Escherichia coli as an active enzyme; the protein was biochemically analyzed. This enolase shares with enolases from other trypanosomatids the presence of three atypical residues, each with a reactive side group, near the active site, already described for the enzyme from ...
Wilfredo, Quiñones +6 more
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Inducible protein stabilization system in Leishmania mexicana
Molecular and Biochemical Parasitology, 2017Targeted regulation of protein levels is an important tool to investigate the role of proteins essential for cell function and development. In recent years, methods based on the Escherichia coli dihydrofolate reductase destabilization domain (ecDHFR DD) have been established and used in various cell types.
Lucie, Podešvová +2 more
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Stable ornithine decarboxylase in promastigotes of Leishmania mexicana mexicana.
Biochemical and biophysical research communications, 1989Studies on the decarboxylation of ornithine in Leishmania mexicana have shown that this activity corresponds to a true ornithine decarboxylase rather than to an oxidative decarboxylation or aminotransferase reaction, both of which also give rise to the release of CO2.
C P, Sánchez +2 more
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The effect of reactive nitrogen intermediates on Leishmania mexicana mexicana
1997Leishmania mexicana mexicana is a protozoan parasite that causes local and diffuse cutaneous leishmaniasis. There are no effective current vaccines, and current drugs have serious side effects. There is a wealth of evidence, both in vitro and in vivo, to suggest that the protective murine immune response involves the production of a set of partially ...
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Transactions of the Royal Society of Tropical Medicine and Hygiene, 1964
R. Lainson, R.S. Bray
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R. Lainson, R.S. Bray
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On the identity of Leishmania mexicana pifanoi and L. mexicana garnhami
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984H, Momen, G, Grimaldi
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