Results 11 to 20 of about 11,204 (214)

Genomic Diversification, Structural Plasticity, and Hybridization in Leishmania (Viannia) braziliensis. [PDF]

Front Cell Infect Microbiol, 2020
Leishmania (Viannia) braziliensis is an important Leishmania species circulating in several Central and South American countries. Among Leishmania species circulating in Brazil, Argentina and Colombia, L. braziliensis has the highest genomic variability.
Patino LH, Muñoz M, Cruz-Saavedra L, Muskus C, Ramírez JD.   +4 more
europepmc   +6 more sources

Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition [PDF]

Frontiers in Microbiology, 2017
Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis.
Erica V. De Castro Levatti, Marcos S. Toledo, Renata Watanabe Costa, Diana Bahia, Diana Bahia, Renato A. Mortara, Helio K. Takahashi, Anita H. Straus   +7 more
doaj   +5 more sources

miR-548d-3p Alters Parasite Growth and Inflammation in <i>Leishmania (Viannia) braziliensis</i> Infection. [PDF]

Front Cell Infect Microbiol, 2021
American Tegumentary Leishmaniasis (ATL) is an endemic disease in Latin America, mainly caused in Brazil by Leishmania (Viannia) braziliensis. Clinical manifestations vary from mild, localized cutaneous leishmaniasis (CL) to aggressive mucosal disease ...
Souza MA, Ramos-Sanchez EM, Muxel SM, Lagos D, Reis LC, Pereira VRA, Brito MEF, Zampieri RA, Kaye PM, Floeter-Winter LM, Goto H.   +10 more
europepmc   +2 more sources

The Influence of Infection by Different Leishmania (Viannia) braziliensis Isolates on the Pathogenesis of Disseminated Leishmaniasis. [PDF]

Front Cell Infect Microbiol, 2021
Disseminated Leishmaniasis (DL) is an emerging and severe form of Leishmania (Viannia) braziliensis infection defined by the presence of 10 and up to more than 1,000 skin lesions. The mechanisms underlying parasite dissemination remain unknown. Genotypic
Oliveira WN, Dórea AS, Carneiro PP, Nascimento MT, Carvalho LP, Machado PRL, Schriefer A, Bacellar O, Carvalho EM.   +8 more
europepmc   +2 more sources

Hybrid reference genome assemblies for <i>Leishmania (Viannia) braziliensis</i>, a primary agent of mucocutaneous leishmaniasis. [PDF]

Microbiol Resour Announc
We report high-quality long-read genome assemblies and annotations for two widely studied reference strains of Leishmania (Viannia) braziliensis, a primary agent of cutaneous and mucocutaneous leishmaniasis.
Cotton JA, Van den Broeck F, Myler PJ, Akopyants NS, Berriman M, Beverley SM.   +5 more
europepmc   +2 more sources

A Virtual Screening Approach to Evaluate the Multitarget Potential of a Chalcone Library with Binding Properties to Oligopeptidase B and Cysteine Proteinase B from <i>Leishmania (Viannia) braziliensis</i>. [PDF]

Int J Mol Sci
Leishmaniasis remains a significant public health problem in Brazil, particularly due to Leishmania (Viannia) braziliensis, which is associated with severe dermatological syndromes.
Monteiro PQ, Schaeffer E, da Silva AJM, Alves CR, Souza-Silva F.   +4 more
europepmc   +2 more sources

Pentavalent Antimony Associated with G-CSF in the Treatment of Cutaneous Leishmaniasis Caused by <i>Leishmania (Viannia) braziliensis</i>. [PDF]

Pathogens
Cutaneous leishmaniasis (CL), caused by Leishmania braziliensis, in recent decades has shown decreasing cure rates after treatment with meglumine antimoniate (MA).
Suprien C, Guimarães LH, de Carvalho LP, Machado PRL.   +3 more
europepmc   +2 more sources

A New Target Organ of Leishmania (Viannia) braziliensis Chronic Infection: The Intestine. [PDF]

Front Cell Infect Microbiol, 2021
Leishmania (Viannia) braziliensis is one of the main causes of cutaneous leishmaniasis in the Americas. This species presents genetic polymorphism that can cause destructive lesions in oral, nasal, and oropharyngeal tracts.
Dos Santos AGA, da Silva MGL, Carneiro EL, de Lima LL, Fernandes ACBS, Silveira TGV, Sant'Ana DMG, Nogueira-Melo GA.   +7 more
europepmc   +2 more sources

Assessing proteases and enzymes of the trypanothione system in subpopulations of Leishmania (Viannia) braziliensis Thor strain during macrophage infection. [PDF]

Mem Inst Oswaldo Cruz
BACKGROUND Leishmania (Viannia) braziliensis Thor strain exhibits a heterogeneous composition comprised of subpopulations with varying levels of infectivity.
Albuquerque-Melo BC, Pereira BAS, Ennes-Vidal V, Gonçalves MEP, Côrtes LMC, Cysne-Finkelstein L, Guedes HLM, Dias-Lopes G, Alves CR.   +8 more
europepmc   +2 more sources

Low doses of 3-phenyl-lawsone or meglumine antimoniate delivery by tattooing route are successful in reducing parasite load in cutaneous lesions of Leishmania (Viannia) braziliensis-infected hamsters. [PDF]

Front Cell Infect Microbiol, 2023
Current therapeutic ways adopted for the treatment of leishmaniasis are toxic and expensive including parasite resistance is a growing problem. Given this scenario, it is urgent to explore treatment alternatives for leishmaniasis.
Meira RMV, Gomes SLDS, Schaeffer E, Da Silva T, Brito ACS, Siqueira LM, Inácio JD, Almeida-Amaral EE, Da-Cruz AM, Bezerra-Paiva M, Neves RH, Rodrigues LS, Dutra PML, Costa PRR, da Silva AJM, Da-Silva SAG.   +15 more
europepmc   +2 more sources