Results 11 to 20 of about 7,677 (256)

Effective Genome Editing in Leishmania (Viannia) braziliensis Stably Expressing Cas9 and T7 RNA Polymerase [PDF]

Frontiers in Cellular and Infection Microbiology, 2021
Until 2015, loss-of-function studies to elucidate protein function in Leishmania relied on gene disruption through homologous recombination. Then, the CRISPR/Cas9 revolution reached these protozoan parasites allowing efficient genome editing with one ...
Caroline R. Espada, Caroline R. Espada, José Carlos Quilles, Andreia Albuquerque-Wendt, Andreia Albuquerque-Wendt, Andreia Albuquerque-Wendt, Mario C. Cruz, Tom Beneke, Lucas B. Lorenzon, Eva Gluenz, Eva Gluenz, Angela K. Cruz, Silvia R. B. Uliana   +12 more
doaj   +2 more sources

Evaluación de la Intradermorreacción con Antígenos de Leishmania (Viannia) peruviana y Leishmania (Viannia) braziliensis en Áreas endémicas de Leishmaniasis en el Perú

Revista Peruana de Medicina Experimental y Salud Pública, 1999
Se elaboró extractos de antígenos solubles de Leishmania (leishmanina), a partir de formas promastigotes de Leishmania (Viannia) peruviana y Leishmania (Viannia) braziliensis.
G Minaya, Y Torres, M Farfán, L Mendizabal, M Colchado, E Arroyo   +5 more
doaj   +1 more source

Big is not better: Comparing two alpha-Gal-bearing glycotopes in neoglycoproteins as biomarkers for Leishmania (Viannia) braziliensis infection. [PDF]

Carbohydr Res, 2023
Montoya AL, Gil ER, Vinales I, Estevao IL, Taboada P, Torrico MC, Torrico F, Marco JD, Almeida IC, Michael K.   +9 more
europepmc   +3 more sources

Toxicity and Anti-promastigote Activity of Benzoxazinoid Analogs Against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum. [PDF]

Adv Pharm Bull, 2020
Purpose: Here, we aim to evaluate the antileishmanial activity of compounds with a benzoxazinoid (BX) skeleton, previously synthesized by our group, against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum promastigotes. Methods: Anti-promastigote activity, as well as cytotoxicity, were determined using the 3-(4,5-dimethylthiazol ...
de Sousa G, Lima WG, Dos Santos FJ, Macías FA, Molinillo JMG, Teixeira-Neto RG, de Siqueira JM, da Silva ES.   +7 more
europepmc   +6 more sources

Evidence of Guanidines Potential against Leishmania (Viannia) braziliensis: Exploring In Vitro Effectiveness, Toxicities and of Innate Immunity Response Effects. [PDF]

Biomolecules, 2023
Dos Anjos LR, de Souza VMR, Machado YAA, Partite VM, Aufy M, Dias Lopes G, Studenik C, Alves CR, Lubec G, Gonzalez ERP, Rodrigues KADF.   +10 more
europepmc   +3 more sources

Low doses of 3-phenyl-lawsone or meglumine antimoniate delivery by tattooing route are successful in reducing parasite load in cutaneous lesions of Leishmania (Viannia) braziliensis-infected hamsters. [PDF]

Front Cell Infect Microbiol, 2023
Meira RMV, Gomes SLDS, Schaeffer E, Da Silva T, Brito ACS, Siqueira LM, Inácio JD, Almeida-Amaral EE, Da-Cruz AM, Bezerra-Paiva M, Neves RH, Rodrigues LS, Dutra PML, Costa PRR, da Silva AJM, Da-Silva SAG.   +15 more
europepmc   +3 more sources

Incidence of Human and Free-Ranging Wild Rodent Infections with Leishmania (Viannia) braziliensis, Aetiological Agent of Cutaneous Leishmaniasis. [PDF]

Pathogens, 2023
Courtenay O, Marinho-Júnior JF, Brito MEF, Monteiro JFCLS, Shaw JJ, Brandão-Filho SP.   +5 more
europepmc   +3 more sources

A Virtual Screening Approach to Evaluate the Multitarget Potential of a Chalcone Library with Binding Properties to Oligopeptidase B and Cysteine Proteinase B from Leishmania (Viannia) braziliensis. [PDF]

Int J Mol Sci
Monteiro PQ, Schaeffer E, da Silva AJM, Alves CR, Souza-Silva F.   +4 more
europepmc   +3 more sources

First report of Leishmania RNA virus 1 in Leishmania (Viannia) braziliensis clinical isolates from Rio de Janeiro State - Brazil. [PDF]

Mem Inst Oswaldo Cruz, 2022
Zabala-Peñafiel A, Fantinatti M, Dias-Lopes G, da Silva JL, Miranda LFC, Lyra MR, Pimentel MIF, Conceição-Silva F, Alves CR.   +8 more
europepmc   +3 more sources

In vitro inhibitory effect of chlorinated tetrasulfonated aluminum phthalocyanine against Leishmania (Viannia) Peruviana and Leishmania (Viannia) Braziliensis

Revista Peruana de Medicina Experimental y Salud Pública, 2020
Objectives: To evaluate the in vitro photodynamic activity of aluminum phthalocyanine tetrasulfonate chloride (AlPc- ClS4) on promastigotes and amastigotes of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis.
Kelly Vanesa Izarra-Rojas, Nyshon Rojas-Palomino, José Luis Gonzáles-Medrano, Gloria Minaya-Gómez, Alfredo Berrocal-Huallpa, Julio Santiago-Contreras, Jorge León-Quispe   +6 more
doaj   +2 more sources