Results 71 to 80 of about 7,677 (256)

Detection and identification of Leishmania species within naturally infected sand flies in the Andean areas of Ecuador by a polymerase chain reaction [PDF]

, 2005
The surveillance of prevalent Leishmania and sand fly species in endemic areas is important for prediction of the risk and expansion of leishmaniasis. In this study, we developed a polymerase chain reaction (PCR)-based method for detection of Leishmania ...
Barroso, Paola Andrea, Calvopina, Manuel, Gomez, Eduardo, Hashiguchi, Yoshihisa, Iwata, Hiroyuki, Katakura, Ken, Kato, Hirotomo, Korenaga, Masataka, Marco, Jorge Diego, Mimori, Tatsuyuki, Nonaka, Shigeo, Uezato, Hiroshi   +11 more
core   +1 more source

Putative markers of infective life stages in Leishmania (Viannia) braziliensis

Parasitology, 2007
SUMMARYGene expression is known to vary significantly during the Leishmania life-cycle. Its monitoring might allow identification of molecular changes associated with the infective stages (metacyclics and amastigotes) and contribute to the understanding of the complex host-parasite relationships.
Gamboa, D., Van Eys, G., Victoir, K., Torres, K., Adaui, V., Arevalo, J., Dujardin, J. C.   +6 more
openaire   +4 more sources

In Situ Evaluation of Macrophage Populations and Inflammasome Components in Cutaneous and Mucocutaneous Leishmaniasis

Parasite Immunology, Volume 47, Issue 9, September 2025.
ABSTRACT American tegumentary leishmaniasis (ATL) affects the skin and mucous membranes, with a spectrum shaped by Th1/Th2 responses. This study investigated inflammasome activation in correlation with macrophage subpopulations, tissue parasitism, and histological changes in cutaneous and mucocutaneous leishmaniasis. We assessed inflammasome activation,
Caroline de Heleno Chagas de Carvalho, Gabriela Venicia Araujo Flores, Carmen Maria Sandoval Pacheco, Vania Lucia da Ribeiro da Matta, Carolina de Esteves de Morais, Ricardo Romiti, Walter Belda Júnior, Márcia Dalastra Laurenti   +7 more
wiley   +1 more source

First Evidence of a Hybrid of Leishmania (Viannia) braziliensis/L. (V.) peruviana DNA Detected from the Phlebotomine Sand Fly Lutzomyia tejadai in Peru. [PDF]

PLoS Neglected Tropical Diseases, 2016
The natural infection of sand flies by Leishmania was examined in the Department of Huanuco of Peru, where cutaneous leishmaniasis caused by a hybrid of Leishmania (Viannia) braziliensis/L. (V.) peruviana is endemic.
Hirotomo Kato, Abraham G Cáceres, Yoshihisa Hashiguchi   +2 more
doaj   +1 more source

Clinical and Parasite Species Risk Factors for Pentavalent Antimonial Treatment Failure in Cutaneous Leishmaniasis in Peru [PDF]

, 2017
Background. Treatment for cutaneous leishmaniasis (CL) with standard pentavalent antimonial therapy is hampered by cumbersome administration, toxicity, and potential failure.
Araujo-Castillo, Roger, Arevalo, Jorge, Boelaert, Marleen, Chappuis, Francois, De Doncker, Simonne, Dujardin, Jean-Claude, Lazo, Marcela, Llanos-Cuentas, Alejandro, Miranda-Verastegui, Cesar, Ramirez, Luis, Robays, Jo, Santamaria-Castrellon, Giovanna, Tulliano, Gianfranco   +12 more
core  

Antileishmanial Activities of Methanol Extract and Solvent Fraction of Clematis simensis Fresen Roots

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Background Leishmaniasis is a neglected tropical disease affecting 12 million people and risks the lives of 350 million people globally. However, it has limited therapeutic options. Clematis simensis Fresen roots are used for the treatment of leishmaniasis in Ethiopian traditional medicine. Objective The aim of this study was to evaluate C.
Amare Megersa, Aschalew Nardos, Tasisa Ketema, Serawit Deyno, Srinivas Mutalik   +4 more
wiley   +1 more source

Cutaneous leishmaniasis in northeastern Brazil: a critical appraisal of studies conducted in State of Pernambuco Leishmaniose cutânea no nordeste do Brasil: uma avaliação crítica dos estudos realizados no Estado de Pernambuco

Revista da Sociedade Brasileira de Medicina Tropical, 2012
American cutaneous leishmaniasis (ACL) is a complex disease with clinical and epidemiological features that may vary from region to region. In fact, at least seven different Leishmania species, including Leishmania (Viannia) braziliensis, Leishmania ...
Maria Edileuza Felinto de Brito, Maria Sandra Andrade, Filipe Dantas-Torres, Eduardo Henrique Gomes Rodrigues, Milena de Paiva Cavalcanti, Alzira Maria Paiva de Almeida, Sinval Pinto Brandão-Filho   +6 more
doaj  

Comparison of Leishmania typing results obtained from 16 European clinical laboratories in 2014. [PDF]

Leishmaniasis is endemic in southern Europe, and in other European countries cases are diagnosed in travellers who have visited affected areas both within the continent and beyond.
Bart, Aldert, Chicharro, Carmen, Chiodini, Peter L, Cortes, Sofia, Davidsson, Leigh, Di Muccio, Trentina, Dujardin, Jean-Claude, Felger, Ingrid, Grimm, Felix, Harms, Gundel, Jaffe, Charles L, Manser, Monika, Paglia, Maria Grazia, Ravel, Christophe, Robert-Gangneux, Florence, Roelfsema, Jeroen, Töz, Seray, Van der Auwera, Gert, Verweij, Jaco J   +18 more
core   +1 more source

Leishmania aethiopica field isolates bearing an endosymbiontic dsRNA virus induce pro-inflammatory cytokine response. [PDF]

, 2014
BACKGROUND: Infection with Leishmania parasites causes mainly cutaneous lesions at the site of the sand fly bite. Inflammatory metastatic forms have been reported with Leishmania species such as L. braziliensis, guyanensis and aethiopica. Little is known
Akopyants, N.S., Beverley, S.M., Desponds, C., Dobson, D.E., Fasel, N., Ghalib, H., Hailu, A., Lye, L.F., Ronet, C., Zangger, H.   +9 more
core   +1 more source

In vitro inhibitory effect of aluminum phthalocyanine tetrasulfonate chloride against Leishmania (Viannia) Peruviana and Leishmania (Viannia) Braziliensis.

Revista peruana de medicina experimental y salud publica, 2021
To evaluate the in vitro photodynamic activity of aluminum phthalocyanine tetrasulfonate chloride (AlPcClS4) on promastigotes and amastigotes of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis.The activity of photodynamic therapy using AlPcClS4 on Leishmania promastigote and amastigotes was determined by the Methyl Thiazole ...
Kelly Vanessa, Izarra-Rojas, Nyshon, Rojas-Palomino, José Luis, Gonzales-Medrano, Gloria, Minaya-Gómez, Alfredo, Berrocal-Huallpa, Julio, Santiago-Contreras, Jorge, León-Quispe   +6 more
openaire   +2 more sources