Results 61 to 70 of about 65,472 (161)

In Situ Evaluation of Macrophage Populations and Inflammasome Components in Cutaneous and Mucocutaneous Leishmaniasis

Parasite Immunology, Volume 47, Issue 9, September 2025.
ABSTRACT American tegumentary leishmaniasis (ATL) affects the skin and mucous membranes, with a spectrum shaped by Th1/Th2 responses. This study investigated inflammasome activation in correlation with macrophage subpopulations, tissue parasitism, and histological changes in cutaneous and mucocutaneous leishmaniasis. We assessed inflammasome activation,
Caroline de Heleno Chagas de Carvalho, Gabriela Venicia Araujo Flores, Carmen Maria Sandoval Pacheco, Vania Lucia da Ribeiro da Matta, Carolina de Esteves de Morais, Ricardo Romiti, Walter Belda Júnior, Márcia Dalastra Laurenti   +7 more
wiley   +1 more source

Clinical, epidemiological and laboratory aspects of patients with American cutaneous leishmaniasis in the State of Pernambuco Aspectos clínicos, epidemiológicos e laboratoriais de pacientes com leishmaniose cutânea americana no Estado de Pernambuco

Revista da Sociedade Brasileira de Medicina Tropical, 2008
The diagnosis for American cutaneous leishmaniasis is based on an association of clinical, epidemiological and laboratory characteristics. The present study identified the circulating species of Leishmania in the State of Pernambuco, described its ...
Luiza de Campos Reis, Maria Edileuza Felinto de Brito, Éricka Lima de Almeida, Simone Marta Félix, Ângela Cristina Rapela Medeiros, Cláudio Júlio Silva, Valéria Rêgo Alves Pereira   +6 more
doaj   +1 more source

Antileishmanial Activities of Methanol Extract and Solvent Fraction of Clematis simensis Fresen Roots

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Background Leishmaniasis is a neglected tropical disease affecting 12 million people and risks the lives of 350 million people globally. However, it has limited therapeutic options. Clematis simensis Fresen roots are used for the treatment of leishmaniasis in Ethiopian traditional medicine. Objective The aim of this study was to evaluate C.
Amare Megersa, Aschalew Nardos, Tasisa Ketema, Serawit Deyno, Srinivas Mutalik   +4 more
wiley   +1 more source

Mucocutaneous Leishmaniasis With Oral Involvement: A Case Report

Case Reports in Dentistry, Volume 2025, Issue 1, 2025.
The primary objective of the present study is the retrospective analysis of a clinical case of oral leishmaniasis treated at Parma Hospital and a review of the literature on mucosal leishmaniasis (ML) with oral cavity involvement. We report the case of a patient diagnosed in 2017 with mucocutaneous leishmaniasis who was referred to our clinic due to ...
Pierpaolo De Francesco, Paolo Vescovi, Claudio Feliciani, Roberta Iaria, Luigi Corcione, Ilaria Giovannacci, Vlaho Brailo   +6 more
wiley   +1 more source

Potential of extracellular vesicles in the pathogenesis, diagnosis and therapy for parasitic diseases

Journal of Extracellular Vesicles, Volume 13, Issue 8, August 2024.
Abstract Parasitic diseases have a significant impact on human and animal health, representing a major hazard to the public and causing economic and health damage worldwide. Extracellular vesicles (EVs) have long been recognized as diagnostic and therapeutic tools but are now also known to be implicated in the natural history of parasitic diseases and ...
Ana Acacia Sá Pinheiro, Ana Claudia Torrecilhas, Bruno Solano de Freitas Souza, Fernanda Ferreira Cruz, Herbert Leonel de Matos Guedes, Tadeu Diniz Ramos, Miqueias Lopes‐Pacheco, Celso Caruso‐Neves, Patricia R. M. Rocco   +8 more
wiley   +1 more source

Leukocyte Behavior in Mesenteric Microcirculation upon Experimental By Leishmania Spp. in BALB/c Mice

Iranian Journal of Parasitology, 2021
Background: We aimed to determine the cellular recruitment (leukocyte rolling and adhesion) by which the Leishmania (Viannia) braziliensis, L. (Leishmania) amazonensis, and L. (Leishmania) major species in the mesenteric microcirculation of BALB/c mice.
Herintha Coeto Neitzke-Abreu, Rhuan Carlos Souza Caetano, Kárin Rosi Reinhold-Castro, Manoel Sebastião da Costa Lima-Junior, Wagner José Tenório dos Santos, Gessilda de Alcantara Nogueira de Melo, Roberto Kenji Nakamura Cuman, Sandra Mara Alessi Aristides, Thais Gomes Verzignassi Silveira, Maria Valdrinez Campana Lonardoni   +9 more
doaj  

On the PhyloQuant protein expression profiles approach to the taxonomic problem

PROTEOMICS, Volume 24, Issue 16, August 2024.
Abstract Inferring evolutionary relationships among organisms has been a fundamental problem in evolutionary biology. The current phylogenetic molecular methods serve as the baseline model to test new evolutionary hypotheses with taxonomic purposes. Leishmaniinae trypanosomatids subfamily includes protozoan parasites of clinical importance to humans ...
Ayixon Sánchez Reyes, Cesar Ayala‐Ruan   +1 more
wiley   +1 more source

An integrated molecular approach for the detection and species-level identification of Leishmania spp. in clinical samples

Microbiology Spectrum
Leishmaniases are parasitic diseases transmitted by infected sand flies, present in over 98 countries. Accurate diagnostic tools are critical for prevention and control, especially in non-endemic areas.
Marikena Guadalupe Risso, Wendy Lorena Quintero-Garcia, Juan Jose Lauthier, Giuliana Saggion, Carlos Parra, Catalina Gauder, German Astudillo, Sofia Echazarreta, Monica Beatriz Foccoli, Ana Andrea Pisarevsky, Silvia Analia Repetto, Paula Ruybal   +11 more
doaj   +1 more source

The in vitro leishmanicidal activity of hexadecylphosphocholine (miltefosine) against four medically relevant Leishmania species of Brazil

Memorias do Instituto Oswaldo Cruz, 2011
The in vitro leishmanicidal activity of miltefosine® (Zentaris GmbH) was assessed against four medically relevant Leishmania species of Brazil: Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, Leishmania (Viannia) guyanensis and ...
Eliane de Morais-Teixeira, Quesia Souza Damasceno, Mariana Kolos Galuppo, Alvaro José Romanha, Ana Rabello   +4 more
doaj   +1 more source

Treatment of mucocutaneous leishmaniasis – A systematic review

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 6, Page 763-773, June 2024.
Summary Mucocutaneous leishmaniasis is a severe infectious disease, predominantly endemic in Central and South America and is characterized by granulomatous, destructive mucosal lesions in the oral, nasal, and pharyngeal cavities. It is caused by protozoa of the genus Leishmania spp. transmitted to humans by sandflies.
Theresa Fischer, Marcellus Fischer, Sibylle Schliemann, Peter Elsner   +3 more
wiley   +1 more source