Results 91 to 100 of about 106,027 (276)

The potential role and apoptotic profile of three medicinal plant extracts on Leishmania tropica by MTT assay, macrophage model and flow cytometry analysis

open access: yesParasite Epidemiology and Control, 2021
Introduction: Treatment of leishmaniasis with conventional synthetic drugs is a major global challenge. This study was designed to explore the leishmanicidal activity and apoptotic profile of three leaf extracts on Leishmania tropica stages. Methods: The
Mozhde Ilaghi   +8 more
doaj  

Leishmaniasis in IBD Patients: Challenges of a Rare Opportunistic Disease

open access: yes
United European Gastroenterology Journal, EarlyView.
Candida Abreu, Rafael Rocha
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

open access: yesMass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Causes of Pediatric Visceral Leishmaniasis in Southeastern Iran

open access: yesIranian Journal of Parasitology, 2014
Leishmania infantum is the most frequent cause of visceral leishmaniasis and L. tropica has been rarely linked to the disease in Iran. In this study, bone marrow aspirates were collected from 10 child patients, suspected with visceral leishmaniasis ...
Ali Hosseininasab   +4 more
doaj  

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

open access: yesAdvanced Therapeutics, Volume 8, Issue 4, April 2025.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap   +10 more
wiley   +1 more source

Real-time PCR applications for diagnosis of leishmaniasis

open access: yesParasites & Vectors, 2018
Leishmaniasis is a vector-borne disease caused by many Leishmania species, which can infect both humans and other mammals. Leishmaniasis is a complex disease, with heterogeneous clinical manifestations ranging from asymptomatic infections to lesions at ...
L. Galluzzi   +4 more
semanticscholar   +1 more source

Escherichia coli in the production of biopharmaceuticals

open access: yesBiotechnology and Applied Biochemistry, Volume 72, Issue 2, Page 528-541, April 2025.
Abstract Escherichia coli has shouldered a massive workload with the discovery of recombinant DNA technology. A new era began in the biopharmaceutical industry with the production of insulin, the first recombinant protein, in E. coli and its use in treating diabetes. After insulin, many biopharmaceuticals produced from E. coli have been approved by the
İbrahim İncir, Özlem Kaplan
wiley   +1 more source

Social and Economic Burden of Human Leishmaniasis.

open access: yesAmerican Journal of Tropical Medicine and Hygiene, 2016
Leishmaniasis continues to pose a major public health problem worldwide. With new epidemics occurring in endemic areas and the spread of the disease to previously free areas because of migration, tourism, and military activities, there is a great need ...
Ifeoma B. Okwor, Jude E. Uzonna
semanticscholar   +1 more source

Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development

open access: yesChemBioChem, Volume 26, Issue 7, April 1, 2025.
Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen   +8 more
wiley   +1 more source

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