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Lenacapavir (Yeztugo) for HIV Pre-Exposure Prophylaxis

The Medical Letter on Drugs and Therapeutics
The FDA has approved oral and injectable formulations of the HIV-1 capsid inhibitor lenacapavir (Yeztugo – Gilead) for pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV-1 in at-risk adolescents and adults. Lenacapavir is the first drug to be approved for this indication that is given twice-yearly; other drugs approved for this
openaire   +2 more sources

Lenacapavir: A Review in HIV Pre-Exposure Prophylaxis

Drugs
Lenacapavir [YEZTUGO® (USA); YEYTUO® (EU)] is the first twice‑yearly long‑acting injectable option to be approved for HIV pre‑exposure prophylaxis (PrEP). As a potent HIV capsid inhibitor, lenacapavir disrupts multiple stages of the viral replication cycle.
openaire   +2 more sources

The road to lenacapavir, a breakthrough HIV treatment

Science
Three individuals have been awarded the AAAS Mani L.
openaire   +1 more source

Lenacapavir Ó? a strong weapon to accelerate HIV prevention

Aids Reviews
Globally, the 2025 prevention target, that is, 95% of people at risk of HIV infection having access to and using effective combination prevention options, is not within reach. Rapid, wider access to pre-exposure prophylaxis (PrEP) could quickly reduce the number of new infections, ultimately among people from key populations.
openaire   +2 more sources

Capsid Inhibition With Lenacapavir in Multidrug-Resistant HIV-1 Infection

New England Journal of Medicine, 2022
Nicolas A Margot   +2 more
exaly  

Lenacapavir: a new treatment of resistant HIV-1 infections

The Lancet Infectious Diseases, 2023
Ammara, Mushtaq, Farooq, Kazi
openaire   +2 more sources

Focus on: lenacapavir

Ahimsa Carissimi   +8 more
openaire   +1 more source

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