Results 101 to 110 of about 4,300,192 (303)

Length-Length and Length-Weight Relationships in Nephrops norvegicus from the Aegean Sea (Linnaeus, 1758)

open access: yesMediterranean Marine Science, 2011
The objective of this study was to determine the length-length, length-width and length-weight relationships inNephrops norvegicus as a basis for conversions. A total of 659 specimens were collected with trawl gears from the commercial trawler “Hapuloğlu” between 17 and 21 August 2008 in international waters of the middle Aegean Sea.
Aydin, C., Aydin, I.
openaire   +4 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Prediction of body weight using body measurements in some sheep and goats in Qatar

open access: yesJournal of Applied Animal Research
The study aimed to identify the relationship between body measurements and the weight of sheep and goats. A total of 324 heads of sheep and 261 heads of goats were used.
Muzzamil Atta   +4 more
doaj   +1 more source

The Length-Weight, Length-Length Relationship and Condition Factor of Angora Loach, Oxynoemacheilus angorae (Steindachner, 1897) Inhabiting Kılıçözü Stream in Kızılırmak River Basin (Central Anatolia-Turkey)

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2016
In this study, length-weight relationship (LWR), length- length relationship (LLR) and condition factor (K) of Angora loach, Oxynoemacheilus angorae were determined. A total of 103 specimens were sampled from Kılıçözü Stream in 2014.
Okan Yazıcıoğlu, Ramazan Yazıcı
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Length-length and Length-weight Relationships in Astacus leptodactylus in Bandar Anzali Region

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 1997
Different length - weight relationship in 1000 male and 201 female of freshwater crayfish were studied and it was revealed that the length - length relationship is best described through linear regression, while weight - length relation is best described through a multimodel one. The "r" coefficient was over 90% in all cases. It was also shown that the
openaire   +4 more sources

Relationship between frequency, length, and treatment outcome of exacerbations to baseline lung function and lung density in alpha-1 antitrypsin-deficient COPD

open access: yesInternational Journal of COPD, 2012
Kesavaperumal Vijayasaratha,1 Robert A Stockley21Lung Investigation Unit, 2Research and Development, University Hospital Birmingham NHS Trust, Birmingham, UKBackground: Diary cards are useful for analyzing exacerbations in chronic obstructive pulmonary ...
Vijayasaratha K, Stockley RA
doaj  

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