Results 81 to 90 of about 4,300,192 (303)
Structural Order for One-Scale and Two-Scale Potentials
, 2006 We perform molecular dynamics simulations to investigate the relationship between structural order and water-like dynamic and thermodynamic anomalies in spherically-symmetric potentials having either one or two characteristic length scales.
Buldyrev, Sergey V. +3 more
core +1 more source
Theoretical Justification for Bond Valence -- Bond Length Empirical Correlations [PDF]
, 2012 Bond valence – bond length empirical correlations are of great interest in chemistry, biology, geology and materials science because they offer a quick and convenient way of checking and evaluating molecular structures.
Hardcastle, F. D., Laffoon, S.
core +3 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Polysemy and brevity versus frequency in language [PDF]
, 2019 The pioneering research of G. K. Zipf on the relationship between word frequency and other word features led to the formulation of various linguistic laws. The most popular is Zipf's law for word frequencies.
Baixeries, Jaume +4 more
core +3 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Bruch´s membrane thickness in relationship to axial length.
PLoS ONE, 2017 PurposeTo assess a potential role of Bruch´s membrane (BM) in the biomechanics of the eye, we measured its thickness and the density of retinal pigment epithelium (RPE) cells in various ocular regions in eyes of varying axial length.MethodsHuman globes ...
Hai Xia Bai +7 more
doaj +1 more source
Relation Between First Arrival Time and Permeability in Self-Affine Fractures with Areas in Contact
, 2012 We demonstrate that the first arrival time in dispersive processes in self-affine fractures are governed by the same length scale characterizing the fractures as that which controls their permeability. In one-dimensional channel flow this length scale is
+7 more
core +3 more sources