Results 81 to 90 of about 4,132,509 (332)
Bogue (Boops boops Linnaeus, 1758) is one of the most economic and common species in Türkiye. The bogue individuals were obtained monthly from the commercial catches of gillnet fisheries from May to August 2024 and purse seine fisheries from September ...
Oğuzhan Ayaz +4 more
doaj +1 more source
Length-Weight Relationships of two Clupeonella species (Clupeidae) from Northwestern Turkey
The length-weight relationships (LWRs) of Clupeonella cultriventris and Clupeonella muhlisi were analysed. Fish samples were collected gill nets (10 mm mesh sized) from the Büyükçekmece Reservoir and Küçükçekmece Lagoon April and June 2016.
Kemal Aydoğan, Müfit Özuluğ
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
In this work the length-weight relationship and the condition factor of Astyanax intermedius parasitised and not by Paracymothoa astyanaxi were analysed in the Grande River.
LM Gomiero, UP Souza, FMS Braga
doaj +1 more source
The objective of this study was to determine the length-length, length-width and length-weight relationships inNephrops norvegicus as a basis for conversions. A total of 659 specimens were collected with trawl gears from the commercial trawler “Hapuloğlu” between 17 and 21 August 2008 in international waters of the middle Aegean Sea.
Aydin, C., Aydin, I.
openaire +4 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source

