Results 81 to 90 of about 4,132,509 (332)

Reproductive Biology of Bogue, Boops boops Linneaus, 1758 in the Aegean Sea and Sea of Marmara, Türkiye

open access: yesAquatic Sciences and Engineering
Bogue (Boops boops Linnaeus, 1758) is one of the most economic and common species in Türkiye. The bogue individuals were obtained monthly from the commercial catches of gillnet fisheries from May to August 2024 and purse seine fisheries from September ...
Oğuzhan Ayaz   +4 more
doaj   +1 more source

Length-Weight Relationships of two Clupeonella species (Clupeidae) from Northwestern Turkey

open access: yesTurkish Journal of Bioscience and Collections, 2020
The length-weight relationships (LWRs) of Clupeonella cultriventris and Clupeonella muhlisi were analysed. Fish samples were collected gill nets (10 mm mesh sized) from the Büyükçekmece Reservoir and Küçükçekmece Lagoon April and June 2016.
Kemal Aydoğan, Müfit Özuluğ
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Condition factor of Astyanax intermedius Eigenmann, 1908 (OSTEICHTHYES, CHARACIDAE) parasitised by Paracymothoa astyanaxi Lemos de Castro, 1955 (CRUSTACEA, CYMOTHOIDAE) in the Grande River, Serra do Mar State Park - Santa Virgínia Unit, São Paulo, Brazil

open access: yesBrazilian Journal of Biology
In this work the length-weight relationship and the condition factor of Astyanax intermedius parasitised and not by Paracymothoa astyanaxi were analysed in the Grande River.
LM Gomiero, UP Souza, FMS Braga
doaj   +1 more source

Length-Length and Length-Weight Relationships in Nephrops norvegicus from the Aegean Sea (Linnaeus, 1758)

open access: yesMediterranean Marine Science, 2011
The objective of this study was to determine the length-length, length-width and length-weight relationships inNephrops norvegicus as a basis for conversions. A total of 659 specimens were collected with trawl gears from the commercial trawler “Hapuloğlu” between 17 and 21 August 2008 in international waters of the middle Aegean Sea.
Aydin, C., Aydin, I.
openaire   +4 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Genetic Architecture and Candidate Genes for Pubescence Length and Density and Its Relationship With Resistance to Common Cutworm in Soybean

open access: gold, 2022
Yawei Li   +12 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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