Results 71 to 80 of about 485,312 (296)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Comparative analysis of carapace length-weight relationship and condition factor of Panulirus stimpsoni and Panulirus japonicus, along Jeju Island, South Korea

open access: yesFisheries and Aquatic Sciences
The economic significance of spiny lobsters, Panulirus japonicus and Panulirus stimpsoni, is substantial in South Korea. However, their biological characteristics are not well documented.
Jun-Hwan Byun   +7 more
doaj   +1 more source

Morphological comparison of western and eastern populations of Caspian kutum, Rutilus kutum (Kamensky, 1901) (Cyprinidae) in the southern Caspian Sea

open access: yesInternational Journal of Aquatic Biology, 2019
This study aimed to investigate morphological differences of western and eastern populations of Caspian kutum Rutilus kutum in the southern Caspian Sea and its providing length-weight relationships and condition factor (CF).
Masoud Sattari   +6 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Variation of the relationships between lengths and weights applied to 123 fish species observed at Réunion Island (Indian Ocean)

open access: gold, 2022
David Roos   +11 more
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Population structure and reproductive biology of Cichla kelberi (Perciformes, Cichlidae) in Lobo Reservoir, Brazil

open access: yesNeotropical Ichthyology
The structure of Cichla kelberi population was characterized regarding the sex ratio, total length composition and some reproductive characteristics. The specimens were collected in two periods, from November 2002 to November 2003 and from December 2004 ...
Jussara E. de Souza   +4 more
doaj   +1 more source

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