Results 71 to 80 of about 1,866,464 (397)

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Determinant factors of senior tourists’ length of stay [PDF]

, 2014
The current tendency to undertake more trips, but of shorter duration, throughout the year, has meant that the tourist industry has started to show greater interest in attracting those market segments that opt for more prolonged stays, as they are ...
Alén, Elisa, Domínguez, Trinidad, Losada, Nieves, Nicolau, Juan Luis   +3 more
core   +2 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

An enigma of hypothyroidism and hyponatremia coexistence: a nationwide population-based retrospective study

BMC Public Health, 2023
Introduction Hypothyroidism is a rare and possible cause of hyponatremia. However, the clinical epidemiology and risk of mortality (ROM) when they coexist still remain elusive.
Chun-Hao Chu, Wu-Chien Chien, Chiung-Chen Liu, Chi-Hsiang Chung, Ying-Chuan Chen, Feng-Chih Kuo, Hung-Hsiang Fang, Cheng-Yi Cheng, Yi-Xuan Ding, Chiung-Hsi Tien, Chien-Ming Lin   +10 more
doaj   +1 more source

Composite Length of Stay, An Outcome Measure of Postoperative and Readmission Length of Stays in Pancreatoduodenectomy

Journal of Gastrointestinal Surgery, 2020
Postoperative length of stay (PLOS) and readmission rate are pancreatoduodenectomy (PD) outcome measures, which are reported individually but may be interrelated. The purpose of this study was to evaluate how well a composite length of stay measure (CLOS) that included PLOS and readmission length of stay describes outcomes.
Gregory A. Williams, Jingxia Liu, William C. Chapman, William G. Hawkins, Ryan C. Fields, Dominic E. Sanford, Majella B. Doyle, Chet W. Hammill, Adeel S. Khan, Steven M. Strasberg   +9 more
openaire   +4 more sources

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

Survey of Elderly Trauma Patients with Prolonged Emergency Department Stays

International Journal of Gerontology, 2008
Background: This study was undertaken to determine the factors occurring in elderly trauma patients that cause emergency department (ED) physicians to spend much time evaluating them, thereby delaying their discharge or admission, and how misdiagnosis or
Wen-Han Chang, Chien-Hsuan Huang, Cheng-Ho Tsai   +2 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Delayed administration of dopaminergic drugs is not associated with prolonged length of stay of hospitalized patients with Parkinson's disease [PDF]

, 2016
Background: Punctual delivery of dopaminergic medication to Parkinson's disease (PD) patients may be important in optimizing disease control. We tested the hypothesis that prompt delivery of l-dopa medications to emergency hospital inpatients was ...
Andrew Fogarty, Barber, Chou, Department of Health, Derry, Domingo-Echaburu, Gerlach, Gerlach, Gerlach, Grosset, Guttman, Hou, Lisa Brown, Low, Magdalinou, Maldonado, Martinez-Ramirez, Ozalp, Parkinson's Disease Society, Pepper, Rob Skelly, Skelly, Skelly, Tan   +23 more
core   +1 more source

Evaluating the Duration of Hospitalization and Its Related Factors Among Stroke Patients

Caspian Journal of Neurological Sciences, 2018
Background: Prolong hospitalization after a stroke is associated with increased cost, higher risk of complications, and adverse effects.  Objectives: The purpose of this study was to determine the length of stay and its related factors among stroke ...
Maedeh Majidi Shad, Alia Saberi, Maryam Shakiba, Shademan Rezamasouleh   +3 more
doaj