Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The determinants of length of stay in the Azores : a count model approach [PDF]
This paper employs count data models to estimate the determinants of length of stay, as count models overcome censoring and truncation data issues associated with the positive integer nature of length of stay.
Menezes, António Gomes de +1 more
core
Ridesharing as an Alternative to Ambulance Transport for Voluntary Psychiatric Patients in the Emergency Department [PDF]
Introduction: Emergency department (ED) crowding is a growing problem. Psychiatric patients have long ED lengths of stay awaiting placement and transportation to a psychiatric facility after disposition.Methods: Retrospective analysis of length of ED ...
Blome, Andrea +3 more
core
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The slowly rotating near extremal D1-D5 system as a `hot tube' [PDF]
The geometry of the D1-D5 system with a small angular momentum j has a long throat ending in a conical defect. We solve the scalar wave equation for low energy quanta in this geometry.
Balasubramanian +28 more
core +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Effect of Kangaroo Mother Care Method Toward Weight Gain and Length of Stay Among Low Birth Weight Baby [PDF]
Infant mortality needs to get serious attention. Special efforts are relatively easy and inexpensive in the handling and care is through treatment methods can improve the stability ofKangaroo Mother Care(KMC) for babies and breastfeeding.The effort ...
Lisnawati, L. (Lisnawati) +1 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Determining Influential Factors on the Length of Stay in the Southeast Hospitals of the Country before and after the Outbreak of the COVID-19 Pandemic [PDF]
Introduction and purpose: The spread of the COVID-19 disease and the increase in healthcare costs have made health care providers look for a solution to evaluate the performance of the healthcare delivery system.
Fatemeh BagherBarahouei +2 more
doaj
Reallocation of beds to reduce waiting time for cardiac surgery [PDF]
Waiting time for cardiac surgery is a significant problem in the current medical world. The fact that patients length of stay varies considerably makes effective hospital operation a hard job. In this paper, the patients length of stay is analyzed. Three
Akkerman, Renzo, Knip, Marrig
core +1 more source

