Results 71 to 80 of about 1,834,359 (305)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Survey of Elderly Trauma Patients with Prolonged Emergency Department Stays

open access: yesInternational Journal of Gerontology, 2008
Background: This study was undertaken to determine the factors occurring in elderly trauma patients that cause emergency department (ED) physicians to spend much time evaluating them, thereby delaying their discharge or admission, and how misdiagnosis or
Wen-Han Chang   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Healthcare data mining: predicting inpatient length of stay [PDF]

open access: yes, 2006
Data mining approaches have been widely applied in the field of healthcare. At the same time it is recognized that most healthcare datasets are full of missing values.
El-Darzi, E.   +11 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Outcome of adult congenital heart disease patients undergoing cardiac surgery: clinical experience of dr. Sardjito hospital

open access: yesBMC Proceedings, 2019
Background Patients with congenital heart disease require surgery to correct the cardiac defect they had in order to prevent heart failure. Unfortunately, data regarding outcome of adult CHD in Indonesia is still limited.
Juni Kurniawaty, Yunita Widyastuti
doaj   +1 more source

One in 100: Behind Bars in America 2008 [PDF]

open access: yes, 2008
Examines the prison population's growth by gender, race/ethnicity, age, and state, and the costs of that growth, including its impact on other state funding priorities.
Jenifer Warren
core  

Outlier admissions of medical patients: Prognostic implications of outlying patients. The experience of the Hospital of Mestre [PDF]

open access: yes, 2015
The admission of a patient in wards other than the appropriate ones, known as the patient outlying phenomenon, involves both Medicine and Geriatric Units of many Hospitals.
Aprile, Anna   +5 more
core   +2 more sources

Implications of decreasing surgical lengths of stay [PDF]

open access: yesAustralian Health Review, 2000
A recent study at the Prince of Wales Hospital (PoW) compared health outcomes and user satisfactionfor conventional clinical pathways with a shortened pathway incorporating day of surgery admission(DOSA), early discharge and post acute care domiciliary visits for two high volume, elective surgicalprocedures (herniorrhaphy and laparoscopic ...
N, Board, G, Caplan
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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