Results 21 to 30 of about 1,156,270 (203)

Ketogenic Diet and Hormonal Therapy in Prevention of Evolution of West Syndrome to Lennox-Gastaut

Pediatric Neurology Briefs, 2009
Medical records of 98 patients diagnosed with West syndrome and monitored at Sanggye Paik Hospital, Seoul, Korea, for at least 3 years were retrospectively reviewed to assess etiology, age at onset, value of various therapies, and the rate of evolution ...
J Gordon Millichap
doaj   +2 more sources

Treatment of Lennox-Gastaut syndrome: overview and recent findings

Neuropsychiatric Disease and Treatment, 2008
Kenou van RijckevorselReference Centre of Refractory Epilepsy, Cliniques Universitaires St Luc, Université Catholique de Louvain, Brussels, BelgiumAbstract: Lennox-Gastaut syndrome (LGS) is a rare, age-related syndrome, characterized by ...
Kenou van Rijckevorsel
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Rufinamide in patients with Lennox-Gastaut syndrome

Nursing: Research and Reviews, 2016
Peggy O Clark,1 Patricia A Gibson2 1Cincinnati Children’s Hospital Medical Center, The University of Cincinnati College of Medicine, Cincinnati, OH, 2Epilepsy Information Service, Wake Forest University School of Medicine, Winston-Salem, NC, USA ...
Clark PO, Gibson PA
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Treatment-resistant Lennox-Gastaut syndrome: therapeutic trends, challenges and future directions

Neuropsychiatric Disease and Treatment, 2017
Adam P Ostendorf,1 Yu-Tze Ng2 1Department of Pediatrics, Neurology Section, Nationwide Children’s Hospital, The Ohio State University, Columbus, OH, 2Department of Pediatrics, Baylor College of Medicine, The Children’s Hospital of San ...
Ostendorf AP, Ng YT
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Treating Lennox–Gastaut syndrome in epileptic pediatric patients with third-generation rufinamide

Neuropsychiatric Disease and Treatment, 2010
Jessica Gresham1, Lea S Eiland2,3, Allison M Chung2,41Auburn University, Harrison School of Pharmacy (AUHSOP), 2Department of Pharmacy Practice, AUHSOP, 3University of Alabama, School of Medicine, Huntsville Regional Medical Campus, 4University of South ...
Jessica Gresham, Lea S Eiland, Allison M Chung   +2 more
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Expanding the electroclinical spectrum of TANC2-related disorders: Lennox-Gastaut syndrome and related developmental epileptic phenotypes. [PDF]

Epilepsia Open
Abstract Objective Neurodevelopmental disorders (NDDs) and epilepsy are often associated. Increasing evidence highlights a pivotal role for pathogenic variants in genes encoding synaptic scaffolding proteins. Within this group, TANC2 has recently been implicated in intellectual developmental disorder with autistic features and language delay, with or ...
Perilli L, Stipa C, Villano G, Licchetta L, Strothmann L, Jauss RT, Kluger GJ, Minardi R, NETRE consortium, Gobbi G, Grosso S, Bisulli F, Striano P.   +12 more
europepmc   +2 more sources

Changes in effectiveness and safety in patients with Lennox-Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open-label extension study. [PDF]

Epilepsia Open
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Nabbout R, Devinsky O, Lagae L, Scheffer IE, Guerrini R, Sullivan J, Gil-Nagel A, Zuberi SM, Riney K, Healy P, Abraham J, Roper RZ, Langlois M, Lothe A, Knupp KG.   +14 more
europepmc   +2 more sources

Therapies for Lennox-Gastaut syndrome [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2005
The treatment of Lennox-Gastaut Syndrome (LGS) has been improved with the introduction of the new anti-epileptic drugs: lamotrigine and topiramate, the employment of a ketogenic diet, and the availability of vagal nerve stimulation.
Đurić Milena
doaj   +1 more source

Improved seizure control and regaining cognitive milestones after vagus nerve stimulation revision surgery in Lennox–Gastaut syndrome

Epilepsy and Behavior Case Reports, 2018
We report a child with Lennox–Gastaut syndrome with an increase in seizure frequency and loss of psychomotor skills due to a disintegrated cervical VNS lead, not detected during standard device monitoring.
Hilde M. Braakman, Joke Creemers, Danny M. Hilkman, Sylvia Klinkenberg, Suzanne M. Koudijs, Mariette Debeij-van Hall, Erwin M. Cornips   +6 more
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Efficacy and Safety of Lamotrigine Adjunctive Therapy in Lennox-Gastaut Syndrome [PDF]

Annals of Child Neurology, 2023
Purpose Lamotrigine (LTG) is often used as adjunctive therapy in Lennox-Gastaut syndrome (LGS); however, it may worsen myoclonic and atypical absence seizures in LGS patients.
Hui Jin Shin, Ara Ko, Se Hee Kim, Joon Soo Lee, Heung Dong Kim, Hoon-Chul Kang   +5 more
doaj   +1 more source