Results 101 to 110 of about 1,156,270 (203)

Update on rufinamide in childhood epilepsy

Neuropsychiatric Disease and Treatment, 2011
Giangennaro CoppolaClinic of Child and Adolescent Neuropsychiatry, Medical School, University of Salerno, ItalyAbstract: Rufinamide is an orally active, structurally novel compound (1-[(2,6-difluorophenil1)methyl1]-1 hydro 1,2,3-triazole-4 carboxamide ...
Coppola G
doaj  

Rufinamide for the treatment of Lennox-Gastaut syndrome: evidence from clinical trials and clinical practice

, 2018
Rufinamide was granted orphan drug status in 2004 for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in patients aged ≥4 years, and was subsequently approved for this indication in several countries, including Europe and the
Santamarina E., Striano P., McMurray R., Falip M.   +3 more
core   +1 more source

Reply to: Does the generalized paroxysmal fast activity‐underrepresented cluster represent Lennox–Gastaut syndrome or other severe developmental and epileptic encephalopathies?

Epilepsia, EarlyView.
Emanuele Cerulli Irelli, Marco Perulli, Maria S. Borioni, Adolfo Mazzeo, Carlo Di Bonaventura, Domenica I. Battaglia   +5 more
wiley   +1 more source

Phenotype‐guided etiologic workup in a prospective cohort of 144 adults with developmental and epileptic encephalopathy

Epilepsia Open, EarlyView.
Abstract Objectives Adults with developmental and epileptic encephalopathies (DEEs) often enter adult neurology care without etiologic clarification because of incomplete transition from pediatric services, outdated investigations, and attenuation of childhood electro‐clinical features over time.
Giuseppe d’Orsi, Umberto Costantino, Maria Teresa Di Claudio, Carmela Pia Ferro, Pietro Palumbo, Mario Benvenuto, Massimiliano Copetti, Leonardo D'Agruma, Massimo Carella, Marco Castori, Orazio Palumbo   +10 more
wiley   +1 more source

La place de la Callosotomie Microchirurgicale dans le traitement du syndrome de Lennox-Gastaut [PDF]

, 2015
Epilepsy is a common neurological disease. The intractable epilepsy is defined by the persistence of disabling seizures despite a well-conducted medical treatment involving the use of antiepileptic drugs and new molecules alone or in combination.
Laghmari, Mehdi, Aniba, Khalid, Ghannane, Houcine, Abardazzou, Abir, Fahde, Youssef, Lmejjatti, Mohamed, Ait Benali, Said   +6 more
core  

Antiepileptic treatment in age-related epileptic encephalopathies: Severe myoclonic epilepsy and Lennox-Gastaut syndrome

, 1996
The authors report 18 patients with Severe Myoclonic Epilepsy and 36 with Lennox-Gastaut Syndrome. Therapeutical approach changed during the follow-up: at the last observation, drugs effective in partial seizures were prescribed more ...
Giovanardi Rossi Paola., Fraticelli Emanuela, Lolli Gloria, Santucci Margherita, Parmeggiani Antonia   +4 more
core   +1 more source

Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome.

, 2011
BACKGROUND: To report on the first multicenter Italian experience with rufinamide as adjunctive drug in children, adolescents and young adults with refractory childhood-onset epileptic encephalopathies other than Lennox-Gastaut syndrome.
Franzoni E, Veggiotti P, Mangano S, Coppola G, Curatolo P, Parisi P, Grosso S, Fels A, Habetswallner F, Spalice A, Pascotto A., VERROTTI DI PIANELLA, Alberto, Balestri A, Zamponi N, D'Aniello A   +14 more
core   +2 more sources

Frequency of anti‐neural antibodies and autoimmune epilepsy in focal epilepsy of unknown etiology: An observational study in a Singaporean cohort

Epilepsia Open, EarlyView.
Abstract Objective Autoimmune epilepsy (AES) is increasingly recognized as a condition in patients with epilepsy of unknown etiology. Early immunotherapy improves outcomes; however, data on its prevalence and the frequency of anti‐neural/neuronal antibodies in Asian populations remain scarce.
Seong Jin Park, Jeanne May May Tan, Xuejuan Peng, Patricia Yut Wan Wong, Karine Su Shan Tay, Angelia Swee Hoon Koe, Janis Siew Noi Tye, Josiah Yui Huei Chai, Pei Xuan Koh, Yee Leng Tan, Sheila Srinivasan, Ngai Kun Loh, Nigel Choon Kiat Tan, Kevin Tan, Tianrong Yeo   +14 more
wiley   +1 more source

Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome. [PDF]

, 2010
Background: To report on the first multicenter Italian experience with rufinamide as adjunctive drug in children, adolescents and young adults with refractory childhoodonset epileptic encephalopathies other than Lennox–Gastaut syndrome.
COPPOLA, Giangennaro, MANGANO S, FELS A, PARISI P, GROSSO S, D'ANIELLO A, FRANZONI E, VEGGIOTTI P, BALESTRI A, PASCOTTO A., HABETSWALLNER F, ZAMPONI N, SPALICE A, VERROTTI A, CURATOLO, P   +14 more
core  

Effectiveness and safety of cannabidiol in adult patients with epilepsy: A multicenter, retrospective study

Epilepsia Open, EarlyView.
Abstract Objective Cannabidiol (CBD) has demonstrated promising effectiveness and tolerability as adjunctive treatment in patients with severe childhood epilepsies. This study investigated the effectiveness and tolerability of CBD in adults with a history of Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), or tuberous sclerosis complex (TSC ...
Sara Sánchez‐Gamino, María Isabel Chamorro Muñoz, Pedro J. Serrano‐Castro, Pablo Hernández‐Vitorique, Lucía Rodríguez Jiménez, Yolanda López Moreno, Pablo Cabezudo‐García, Guillermina García Martín   +7 more
wiley   +1 more source