Results 51 to 60 of about 2,709,539 (294)

Using an identity lens : constructive working with children in the criminal justice system [PDF]

, 2020
Research has shown that identity, and how you feel about yourself, can be key to moving forward with life and away from crime. Working with the University of Salford, Youth Offending Teams and supported by the Barrow Cadbury Trust, this resource has been
Drummond, C, Hazel, N, Joseph, K, Nacro, Welsh, M   +4 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Gold Nanostars Bioconjugation for Selective Targeting and SERS Detection of Biofluids

Nanomaterials, 2021
Gold nanoparticles (AuNPs) show physicochemical and optical functionalities that are of great interest for spectroscopy-based detection techniques, and especially for surface enhanced Raman spectroscopy (SERS), which is capable of providing detailed ...
Caterina Dallari, Claudia Capitini, Martino Calamai, Andrea Trabocchi, Francesco Saverio Pavone, Caterina Credi   +5 more
doaj   +1 more source

Glide-Symmetric Fully Metallic Luneburg Lens for 5G Communications at Ka-Band

IEEE Antennas and Wireless Propagation Letters, 2018
Here, we propose a fully metallic implementation of a Luneburg lens operating at Ka-band with potential use for 5G communications. The lens is implemented with a parallel plate that is loaded with glide-symmetric holes.
O. Quevedo–Teruel, Jingwei Miao, M. Mattsson, A. Algaba-Brázalez, M. Johansson, L. Manholm   +5 more
semanticscholar   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Highly inclined light sheet allows volumetric super-resolution imaging of efflux pumps distribution in bacterial biofilms

Scientific Reports
Bacterial biofilms are highly complex communities in which isogenic bacteria display different gene expression patterns and organize in a three-dimensional mesh gaining enhanced resistance to biocides.
T. Vignolini, M. Capitanio, C. Caldini, L. Gardini, F. S. Pavone   +4 more
doaj   +1 more source

Optical mapping of neuronal activity during seizures in zebrafish

Scientific Reports, 2017
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a better understanding of the mechanisms underlying this pathology and improve our approaches to the development of new drugs.
L. Turrini, C. Fornetto, G. Marchetto, M. C. Müllenbroich, N. Tiso, A. Vettori, F. Resta, A. Masi, G. Mannaioni, F. S. Pavone, F. Vanzi   +10 more
doaj   +1 more source

Visual performance with changes in eccentricity in PROSE device: A case report

Journal of Optometry, 2014
This case report describes the variations in visual performance of a subject with moderate keratoconus with changes in front surface eccentricities (FSEs) of PROSE (Prosthetic Replacement of Ocular Surface Ecosystem).
Divya Jagadeesh, Rajeswari Mahadevan
doaj   +1 more source

REVIEW: Truly critical and honest appraisals of The Guardian’s record as a guardian of power still needed

Pacific Journalism Review, 2021
Capitalism’s Conscience: 200 Years of the Guardian, edited by Des Freedman. London: Pluto Press. 2021, 320 pages. ISBN 9780745343341; 9780745343358 A collection of essays, Capitalism’s Conscience—200 Years of the Guardian, has been recently published.
David Edwards
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source