Results 61 to 70 of about 1,022,216 (261)

Cyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative Diseases

open access: yesMolecules, 2016
Cardiovascular diseases, like atherosclerosis, and neurodegenerative diseases affecting the central nervous system (CNS) are closely linked to alterations of cholesterol metabolism. Therefore, innovative pharmacological approaches aiming at counteracting
Caroline Coisne   +5 more
doaj   +1 more source

The radar signature of the Wind Lens: a less disruptive wind turbine? [PDF]

open access: yes, 2012
We study the radar signature of a new type of wind turbine, named the Wind Lens. This design includes a flanged shroud around the turbine which concentrates the wind flow past the turbine blades and hence improves the efficiency.
H. Griffiths   +9 more
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

NEW OPTION IN CONVENTIONAL SILICONE HYDROGEL CONTACT LENSES: THE BRAZILIAN EXPERIENCE

open access: yesVision Pan-America, 2015
PURPOSE: To evaluate the clinical performance of a new conventional silicone hydrogel contact lens in spherical and toric designs. METHODS: We fitted the Perfect SH and Perfect Toric SH (World Vision Ophthalmic®, Brazil) in 19 patients (33 ...
Marcelo Vicente de Andrade Sobrinho   +4 more
doaj   +1 more source

Evaluation of the microstructure of cornea by in vivo confocal microscopy in contact lens wearing and non-contact lens wearing keratoconus patients

open access: yes, 2010
Purpose: To compare the microstructure of the central keratoconic cornea in contact lens wearing and non-contact lens wearing keratoconus ...
Yilmaz, Senay   +5 more
core   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Refined Mapping of Endothelial Cells, Brain Pericytes and Astrocytes Proteomes via Subcellular Fractionation and DDA Mass Spectrometry

open access: yesBiology
Proteomic profiling of brain microvascular cells, i.e., endothelial cells, brain pericytes, and glial cells, is essential for understanding their distinct roles in the neurovascular unit. In this study, we present a comparative data-dependent acquisition
Océane Dusailly   +9 more
doaj   +1 more source

The effect of soft lens lubricants on symptoms and lens dehydration

open access: yes, 1991
In order to establish the efficacy of soft lens lubricants and their mode of action, we conducted a controlled, double-masked, randomized study. Symptoms of dryness as well as lens water content were assessed in 30 symptomatic hydroxyethylmethacrylate ...
Efron, Nathan   +2 more
core  

Air lens vs aspheric surface: a lens design case study

open access: yes, 2017
We discuss the behavior of air lenses in lens design. The structural aberration coefficients of a thin air lens are derived and compared with their glass thin lens counterpart.
Weichuan Gao   +3 more
core   +1 more source

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