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Inhibitory effect of sulfated lentinan and lentinan against tobacco mosaic virus (TMV) in tobacco seedlings

International Journal of Biological Macromolecules, 2013
The antiviral activities of sulfated lentinan (sLNT) and lentinan (LNT) against tobacco mosaic virus (TMV) in tobacco seedlings and the underlying mechanism were investigated. Compared with LNT, sLNT showed significantly higher inhibitory effects on viral infection and TMV multiplication in a dose-dependent way, which might be due to its binding with ...
Jie, Wang   +4 more
openaire   +2 more sources

Protective activity of Lentinan in experimental tuberculosis

International Immunopharmacology, 2003
Protective effects of Lentinan (Ajinomoto, Japan) against Mycobacterium tuberculosis infection were studied by in vitro and in vivo mouse models. The effectiveness of Lentinan administrated intraperitoneally (i.p.) before infection at a dose of 1 mg/kg three times at 2-day intervals was monitored in vivo by several parameters (body temperature; spleen ...
Nadya, Markova   +5 more
openaire   +2 more sources

Clinical Efficacy of Lentinan on Neoplastic Diseases

1983
Lentinan, a β-(1-3)-glucan with some β-(1-6)-gluco-pyranoside branchings, has been extracted and purified from Lentinus edodes a most popular edible mushroom in Japan. This substance has been shown to act as an immunostimulating agent through host defense mechanisms as reported by Chihara et al (1, 2).
T, Taguchi   +5 more
openaire   +2 more sources

Lentinan PLGA-stabilized pickering emulsion for the enhanced vaccination

International Journal of Pharmaceutics, 2022
Lentinan (LNT), a β-1,3-linked-d-glucan with β-1,6 glucose branches, is the main bioactive component extracted from Lentinus edodes. As a carbohydrate polymer, it has attracted increasingly attention because of immune enhancement effect. Pickering emulsion has been widely used in biomedicine due to its great stability, high loading capacity, and ...
Lina, Jiao   +8 more
openaire   +2 more sources

Lentinan and other antitumoral polysaccharides

1999
Despite a great deal of effort made by many researchers throughout the world, chemotherapeutic agents that attack cancer cells directly do not seem to have the expected effects except on some leukaemias. Besides, these agents show strong toxicity to the host, and reduce the host defense against infections, especially destroying lymphocytes and bone ...
Yukiko Y. Maeda, Goro Chihara
openaire   +1 more source

Histamine sensitizing activity of lentinan, an antitumour polysaccharide

Experientia, 1973
E dimostrato che lentinan, polisaccaride antineoplastic, e capace di aumentare la sensibitita del topo contro istamina. La presomministrazione di lentinan invece non aumenta l'attivita del fattore istamina sensibilizzante dellaBordetella pertussis. Lentinan non induce linfocitose nel topo.
R, Homma, K, Kuratsuka
openaire   +2 more sources

Quality evaluation of lentinan injection produced in China

Journal of Pharmaceutical and Biomedical Analysis, 2013
Lentinan is a β-(1→6) branched β-(1→3)-glucan derived from Lentinula edodes mushroom. It has been developed as an adjuvant to cancer chemotherapy and clinically used in Japan and China. Up to date, six lentinan injections or powders for injection produced by individual manufacturers were widely used in clinic in China.
Y W, Chen   +6 more
openaire   +2 more sources

The esterified lentinan bilayer nanofibrous membrane for promoting wound healing

Carbohydrate Polymers, 2022
Host reactions following implantation of biomaterials, especially the macrophages' responses could significantly affect the wound healing process. Therefore, it is meaningful to develop immunostimulatory active wound dressing to accelerate wound healing.
Qiang, Ding   +7 more
openaire   +2 more sources

Some Novel Pharmacological Properties of Lentinan

1990
Lentinan (LTN), a natural polysaccharide isolated from the mushroom Lentinus edodes, is known to have a number of biological activities. Lentinan augments the host resistance to bacterial and viral infections and shows an antitumor activity (Suga et al. 1986).
K. Mašek   +5 more
openaire   +1 more source

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