Results 181 to 190 of about 116,783 (314)

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo   +12 more
wiley   +1 more source

Purification of Human CD34+CD90+ HSCs Reduces Target Cell Population and Improves Lentiviral Transduction for Gene Therapy. [PDF]

open access: yesMol Ther Methods Clin Dev, 2020
Radtke S   +10 more
europepmc   +1 more source

Redirecting T Cells to Ewing's Sarcoma Family of Tumors by a Chimeric NKG2D Receptor Expressed by Lentiviral Transduction or mRNA Transfection

open access: gold, 2012
Manfred Lehner   +13 more
openalex   +2 more sources

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

open access: yesAdvanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun   +6 more
wiley   +1 more source

A novel pseudotype derived of the canine distemper virus for adapter-mediated lentiviral transduction <i>in vivo</i>. [PDF]

open access: yesMol Ther Methods Clin Dev
Winter N   +12 more
europepmc   +1 more source

Hypoxia drives HIF2-dependent macrophage cell cycle entry and susceptibility to lentiviral transduction

open access: yes, 2023
Meng B   +11 more
europepmc   +1 more source

Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein Receptor. [PDF]

open access: yesMol Ther Methods Clin Dev, 2020
Gong Y   +5 more
europepmc   +1 more source

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