Results 181 to 190 of about 115,363 (220)

Lentiviral Vectors: From Wild-Type Viruses to Efficient Multi-Functional Delivery Vectors. [PDF]

open access: yesInt J Mol Sci
Arrasate A   +6 more
europepmc   +1 more source

Hematopoietic stem cell therapy with gene modification to treat sickle cell disease. [PDF]

open access: yesStem Cells Transl Med
Ball J   +4 more
europepmc   +1 more source
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Lentiviral Transduction of Neuronal Cells

2021
Lentiviruses are a very reliable class of viral vectors wildly used in gene therapy. In this chapter, we described a general method for the construction of lentiviral delivery system by using a derived HIV-1 based lentivirus expression vector pKLV-Puro containing a monomeric blue fluorescent protein mammalian codon-optimized (TagBFP).
Anna, Bellizzi   +2 more
openaire   +2 more sources

Lentiviral Gene Transduction of Kidney

Human Gene Therapy, 2002
Gene transfer into kidney holds great potential as a novel therapeutic approach. We have studied the transduction of kidney in vivo after delivery of lentiviral vectors by various routes of administration. A lentiviral vector expressing the bacterial lacZ gene from the cytomegalovirus early promoter was used.
G Luca, Gusella   +5 more
openaire   +2 more sources

Lentiviral transduction of murine oligodendrocytes in vivo

Journal of Neuroscience Research, 2005
Lentiviral vectors are used widely to direct efficient gene transfer in vivo. We examined cell-specific expression in adult murine white matter after stereotaxic microinjection of four lentiviral constructs. We synthesized vesicular stomatitis virus glycoprotein (VSV-G) pseudotyped lentiviruses with combinations of two promoters, cytomegalovirus (CMV ...
Sally R, McIver   +6 more
openaire   +2 more sources

Lentiviral Transduction of Cultured Microglia

2013
Microglial cells are the resident immune-related glial cells of the central nervous system (CNS) that are crucial for maintaining homeostasis and sensing pathological alterations in the nervous system. To improve our understanding of the biological function of microglia, gene-transfer techniques have been improved and become widely used over the past ...
Takahiro, Masuda   +3 more
openaire   +2 more sources

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