Results 231 to 240 of about 1,111,723 (286)

Envelope protein-specific B cell receptors direct lentiviral vector tropism in vivo. [PDF]

Mol Ther
Takano KA, Wong AAL, Brown R, Situ K, Chua BA, Abu AE, Pham TT, Reyes GC, Ramachandran S, Kamata M, Li MMH, Wu TT, Rao DS, Arumugaswami V, Dorshkind K, Cole S, Morizono K.   +16 more
europepmc   +1 more source

T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector. [PDF]

NPJ Vaccines
Fert I, Douguet L, Vesin B, Moncoq F, Noirat A, Authié P, Ciret S, Le Chevalier F, Blanc C, Vitrenko Y, Charneau P, Majlessi L, Anna F.   +12 more
europepmc   +1 more source

Duchenne muscular dystrophy treatment with lentiviral vector containing mini-dystrophin gene in vivo. [PDF]

MedComm (2020)
Wang X, Zhu Y, Liu T, Zhou L, Fu Y, Zhao J, Li Y, Zheng Y, Yang X, Di X, Yang Y, He Z.   +11 more
europepmc   +1 more source

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.

Blood
Castruccio Castracani C, Breda L, Papp TE, Guerra A, Radaelli E, Assenmacher CA, Finesso G, Mui BL, Tam YK, Fontana S, Riganti C, Fiorito V, Petrillo S, Tolosano E, Parhiz H, Rivella S.   +15 more
europepmc   +1 more source

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Lentiviral Vectors

2005
We review the use of lentiviral vectors in current human gene therapy applications that involve genetic modification of nondividing tissues with integrated transgenes. Safety issues, including insertional mutagenesis and replication-competent retroviruses, are discussed.
Nils, Loewen, Eric M, Poeschla
openaire   +2 more sources

Lentiviral Vectors

2011
Lentiviral vectors have evolved over the last decade as powerful, reliable, and safe tools for stable gene transfer in a wide variety of mammalian cells. Contrary to other vectors derived from oncoretroviruses, they allow for stable gene delivery into most nondividing primary cells.
Giry-Laterrière M, Verhoeyen E, Salmon P   +2 more
openaire   +3 more sources

Lentiviral Vector Targeting

2002
After more than a decade of consternation over the lack of convincing efficacy data from the early gene therapy clinical trials, the recent reports of CAVAZZANA et al. (2000) and ABONOUR et al. (2000) have brought to gene therapists and their patients a new wave of optimism.
A, Larochelle, K W, Peng, S J, Russell
openaire   +2 more sources

Nonprimate Lentiviral Vectors

2002
Advances in the nascent field of gene therapy have created a demand for gene transfer vehicles that are capable of safely and stably delivering genes to both dividing and nondividing cells. Retroviral vectors, by virtue of their ability to permanently integrate genes of interest into the target cell genome, have played a prominent role in much of the ...
M A, Curran, G P, Nolan
openaire   +2 more sources

Immune Responses to Lentiviral Vectors

Current Gene Therapy, 2007
Efficient delivery and sustained expression of a therapeutic gene into human tissues are the requisite to accomplish the high expectations of gene therapy. A major challenge has concerned development of gene transfer systems capable of efficient cell transduction and transgene expression without harm to the recipient.
FOLLENZI, Antonia, SANTAMBROGIO L, ANNONI A.   +2 more
openaire   +3 more sources

Production and Titration of Lentiviral Vectors

Current Protocols in Neuroscience, 2010
AbstractLentiviral vectors have emerged over the last decade as powerful, reliable, and safe tools for stable gene transfer in a wide variety of mammalian cells. Unlike other vectors derived from oncoretroviruses, they allow for stable gene delivery into most nondividing primary cells, including neurons.
Barde, Isabelle, Salmon, Patrick, Trono, Didier   +2 more
openaire   +4 more sources