Results 281 to 290 of about 202,804 (290)

Cell Cycle‐Specific Regulation of Centrosome Clustering Dynamics in Cancer Cells by the Multifunctional Kinesin HSET

Advanced Science, EarlyView.
CDK5RAP2 associates with the kinesin HSET and forms co‐condensates. HSET motors drive the directional transport of CDK5RAP2 condensates toward microtubule minus ends. During mitosis, HSET self‐assembly further stabilizes clustered centrosomes, thereby enabling pseudo‐bipolar spindle formation in cancer cells with supernumerary centrosomes. Upon mitotic
Po‐Pang Chen, Athira Saju, Chia‐Chou Wu, Tzu‐Han Weng, Su‐Yi Tsai, Tzu‐Lun Huang, Jia‐Ying Su, Chien‐Ling Lin, Yu‐Chun Lin, See‐Yeun Ting, Sheng‐hong Chen, Kuo‐Chiang Hsia   +11 more
wiley   +1 more source

IRF6 induces endothelial dysfunction through the transcriptional activation of NDRG1 and aggravates low shear stress-mediated atherosclerosis. [PDF]

iScience
Chen Y, Zhang Y, Rui S, Dong B, Xu X, Jin Y.   +5 more
europepmc   +1 more source

Programmable RNA N6,2´‐O‐Dimethyladenosine Editing

Advanced Science, EarlyView.
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li, Xiangmin Tan, Yaran Liu, Yongquan He, Bo Yuan, Ping Wang, Guangzhi Ma, Mengzhe Guo, Jian Zhou, Qiang Sun   +9 more
wiley   +1 more source

Long-term atorvastatin improves cognitive function by modulating SIRT2-mediated dynamic transition of NFL lysine 272 crotonylation to ubiquitination in naturally aging rats. [PDF]

Cell Death Discov
Xu TC, Cai JR, Chen HS.
europepmc   +1 more source

PRRSV-2 impedes lysosomes from eliminating secondary infected bacteria. [PDF]

PLoS Pathog
Zheng Z, Ling X, Qiao S, Wu J, Zhang S, Liu X, Li Y, Xie C, Ma Z, Guo X, Li Z, Feng Y, Xu L, Zhang J, Zheng H, Xiao S.   +15 more
europepmc   +1 more source

Loss of KDM5A-mediated H3K4me3 demethylation promotes aberrant neural development by Wnt/β-catenin pathway activation. [PDF]

Cell Death Dis
Li J, Liang Y, Cao Z, Xie Q, Gu X, Ma P, Li L, Ren W, Fu Y, Liu Z, Wang Y, Zhang T, Yang H, Yang S, Xie J.   +14 more
europepmc   +1 more source

Novel rabies vaccine candidates development based on pseudotyped lentiviral vectors with rabies virus glycoprotein. [PDF]

PLoS Negl Trop Dis
Shuai L, Xu M, Pei N, Zhu C, Belghait M, Hu Z, Li J, Li H, Mao Y, Du H.   +9 more
europepmc   +1 more source

Sohlh2 inhibited the angiogenesis of hepatocellular carcinoma through the HIF-1α/VEGFA pathway. [PDF]

Transl Oncol
Liu Q, Zhang Y, Wu Y, Chen S, Wang J.
europepmc   +1 more source

Aspects of reproduction and lentivirus epidemiology in small ruminants

, 2007
Kevin Peterson
openalex   +1 more source

APOBEC3B enhances the efficacy of PARP inhibitors in elimination of ovarian cancer stem cell. [PDF]

Sci Rep
Rivera M, Liu L, Enlund S, Lim CE, Zhang H, Yang K, Sasik R, Crews LA, Fisch KM, Eskander RN, Holm F, Jiang Q.   +11 more
europepmc   +1 more source