Results 51 to 60 of about 98,106 (307)

Nucleolar Localization of HIV-1 Rev Is Required, Yet Insufficient for Production of Infectious Viral Particles. [PDF]

, 2018
Combination antiretroviral therapy fails in complete suppression of HIV-1 due to drug resistance and persistent latency. Novel therapeutic intervention requires knowledge of intracellular pathways responsible for viral replication, specifically those ...
Arizala, Jerlisa Ann C, Burnett, John C, Li, Haitang, Ouellet, Dominique L, Rossi, John J, Takahashi, Mayumi   +5 more
core   +1 more source

Small scale Lentivirus Production and Infection v1

, 2022
This protocol can be used for production and transduction of lentiviral sgRNA, shRNA and protein overexpression in conjunction with generation 2 and generation 3 lentivirus plasmids.
Herschel Dhekne, Suzanne R Pfeffer
openaire   +1 more source

Lentivirus infection of macrophages.

Immunology series, 1994
The ovine and caprine lentiviruses infect monocytes, and the viral DNA is integrated into the cellular DNA. The provirus remains silent until the monocyte matures into a macrophage. Intrinsic to this maturation is the induction of a class of immediate early genes in the monocyte that includes the transcription factors JUN and FOS.
J E, Clements, M C, Zink, O, Narayan, D H, Gabuzda   +3 more
openaire   +3 more sources

Inhibition of feline leukemia virus replication in chronically infected cell line utilizing RNA interference [PDF]

, 2012
Feline Leukemia virus (FeLV) is a pathogenic retrovirus endemic among domestic cats, remaining a serious disease since its discovery in 1964. RNA interference (RNAi) is a process in which double-stranded RNA induces the post-transcriptional sequence ...
Barra, Gustavo Barcelos, Kanzaki, Luis Isamu Barros, Ornelas, Sócrates Souza   +2 more
core   +1 more source

Seropositivity for Maedi-Visna virus in sheep in Porto Acre city – Western Amazon, Brazil

Ciência Animal Brasileira, 2020
Lentivirosis of small ruminants (LVPR) are chronic and degenerative infectious diseases, caused by Lentivirus, associated with numerous losses such as: drop in meat and milk production, predisposition to secondary infections, expenses with veterinary ...
Karolyne Teixeira Vinha, Tamyres Izarelly Barbosa da Silva   +1 more
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Clinical Aspects of Feline Retroviruses: A Review [PDF]

, 2012
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses with global impact on the health of domestic cats. The two viruses differ in their potential to cause disease.
Ackley, Anderson, Barlough, Barnett, Barr, Beatty, Beatty, Beatty, Bishop, Bishop, Brightman, Brown, Callanan, Callanan, Carmichael, Choi, Cotter, Cotter, Cotter, Court, Cullen, Day, Dean, Diehl, Dow, Ellis, English, Essex, Fleming, Flynn, Francis, Garg, Gunn-Moore, Hara, Hardy, Harrus, Heit, Hoffmann-Fezer, Hofmann-Lehmann, Holznagel, Hoover, Hoover, Hutson, Jackson, Jarrett, Johnson, Joshi, Katrin Hartmann, Kipar, Kohn, Kubes, Lauring, Levy, Levy, Levy, Liang, Linenberger, Lott-Stolz, Matsumoto, Mitchell, Mizuno, Mizuno, Mizuno, Mortola, Mortola, Novotney, O'Connor, Ohno, Ohno, Overbaugh, Pedersen, Pedersen, Phillips, Phipps, Podell, Podell, Pool, Power, Prospero-Garcia, Quackenbush, Reinacher, Rickard, Ritchey, Rohn, Schrenzel, Sellon, Sellon, Sheets, Shelton, Shelton, Shimojima, Shimojima, Stiles, Taniguchi, Tompkins, Torten, Tsatsanis, Willett, Willett, Zaccaro, Zhao   +100 more
core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Impaired Expression of Cytokines as a Result of Viral Infections with an Emphasis on Small Ruminant Lentivirus Infection in Goats

Viruses, 2016
Knowing about the genes involved in immunity, and being able to identify the factors influencing their expressions, helps in gaining awareness of the immune processes.
Justyna Jarczak, Jarosław Kaba, Daria Reczyńska, Emilia Bagnicka   +3 more
doaj   +1 more source

CRISPR/Cas9 as a therapeutic tool for triple negative breast cancer: from bench to clinics

Frontiers in Molecular Biosciences, 2023
Clustered regularly interspaced short palindromic repeats (CRISPR) is a third-generation genome editing method that has revolutionized the world with its high throughput results.
Prashant Kumar Tiwari, Tin-Hsien Ko, Rajni Dubey, Mandeep Chouhan, Lung-Wen Tsai, Lung-Wen Tsai, Lung-Wen Tsai, Himanshu Narayan Singh, Kundan Kumar Chaubey, Deen Dayal, Chih-Wei Chiang, Chih-Wei Chiang, Sanjay Kumar   +12 more
doaj   +1 more source