Results 241 to 250 of about 242,212 (304)

Protein-truncating variants in APBA1 in minors with severe, early-onset obesity: implications for genetic testing. [PDF]

Mol Cell Pediatr
Lerner J, Moawia A, Zorn S, Kloker S, Klehr-Martinelli M, Winner K, Penfold D, Völkl TMK, Krausnick M, Siebert R, Wabitsch M.   +10 more
europepmc   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source

Multidimensional Analysis of Serum Adiponectin, Leptin, and Resistin Levels and Their Correlation with Childhood Obesity Based on Gut Microbiota and Inflammatory Markers: A Single-Center Cross-Sectional Retrospective Study. [PDF]

Int J Gen Med
Wang X, Wu Y, Zhang X.
europepmc   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Exploring <i>LEPR</i>-Linked Metabolic Diversity through Gut Microbiome-Metabolome Network Analysis in Non-Obese Adults. [PDF]

Biomol Ther (Seoul)
Kim KS, Cho JY, Park YC, Hong JH, Jung JG, Sunwoo J.   +5 more
europepmc   +1 more source

Association Between Frailty and Leptin Levels in Patients with Stable Coronary Artery Disease. [PDF]

Diagnostics (Basel)
Krivoshapova K, Tsygankova D, Neeshpapa A, Kareeva A, Kokov A, Bazdyrev E, Karetnikova V, Barbarash O.   +7 more
europepmc   +1 more source

Metabolic syndrome and risk of advanced colorectal adenomas in a screening population: Frequentist and Bayesian analyses. [PDF]

Colorectal Dis
Singhartinger F, Semmler G, Paar V, Lichtenauer M, Völkerer A, Holzinger J, Ausserwinkler M, Flamm M, Aigner E, Datz C, Wernly B.   +10 more
europepmc   +1 more source

Diagnostic and immunological roles of leptin gene rs7799039 polymorphism and cytokines in COVID-19, HCV, and dual infection. [PDF]

Sci Rep
Sakr AA, Ahmed AE, Hasona NA, Abdel-Hamid RM, Faisal AS, Shaaban EE, Mohamed S, Abbas AM, Mohamed AA.   +8 more
europepmc   +1 more source

Wellness testing in blood donation: A framework for responsible innovation

Transfusion, EarlyView.
Jeremy W. Jacobs, Sheharyar Raza, Brian D. Adkins, Victoria Costa, David M. Chooljian, Garrett S. Booth   +5 more
wiley   +1 more source

Maternal Determinants of Human Milk Leptin and Their Associations with Neonatal Growth Parameters. [PDF]

Nutrients
Garro-Aguilar Y, Astigarraga E, Barreda-Gómez G, Martinez O, Simón E.   +4 more
europepmc   +1 more source